MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial-mesenchymal transition (Q37198652)

18 August 2017

MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial-mesenchymal transition (English)

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18 August 2017

H Rajabi

1

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18 August 2017

M Alam

2

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18 August 2017

H Takahashi

3

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18 August 2017

A Kharbanda

4

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18 August 2017

M Guha

5

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18 August 2017

R Ahmad

6

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18 August 2017

D Kufe

7

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18 August 2017

language of work or name

English

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publication date

15 April 2013

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18 August 2017

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18 August 2017

33

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18 August 2017

13

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18 August 2017

1680-1689

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describes a project that uses

18 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3783575/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/onc.2013.114

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cites work

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Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells

6 September 2017

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MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches

6 September 2017

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MUC1-C oncoprotein confers androgen-independent growth of human prostate cancer cells

6 September 2017

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MUC1-C oncoprotein induces TCF7L2 transcription factor activation and promotes cyclin D1 expression in human breast cancer cells

6 September 2017

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Targeting cysteine-mediated dimerization of the MUC1-C oncoprotein in human cancer cells

6 September 2017

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A monoclonal antibody against the oncogenic mucin 1 cytoplasmic domain

6 September 2017

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β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness.

6 September 2017

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MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop

6 September 2017

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MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

6 September 2017

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MUCIN 1 ONCOPROTEIN EXPRESSION IS SUPPRESSED BY THE miR-125b ONCOMIR

6 September 2017

1 reference

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The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?

6 September 2017

1 reference

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IAP regulation of metastasis

6 September 2017

1 reference

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Epithelial-mesenchymal transitions in development and disease

6 September 2017

1 reference

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Mucins in cancer: function, prognosis and therapy

6 September 2017

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

MUC1-C oncoprotein functions as a direct activator of the nuclear factor-kappaB p65 transcription factor

6 September 2017

1 reference

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Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells

6 September 2017

1 reference

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Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

The role of the ZEB family of transcription factors in development and disease.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition

6 September 2017

1 reference

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Generation of breast cancer stem cells through epithelial-mesenchymal transition

6 September 2017

1 reference

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6 September 2017

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The epithelial-mesenchymal transition generates cells with properties of stem cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

ERK and PI3K regulate different aspects of the epithelial to mesenchymal transition of mammary tumor cells induced by truncated MUC1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

Spatial and temporal recruitment of androgen receptor and its coactivators involves chromosomal looping and polymerase tracking

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

An IkappaBalpha inhibitor causes leukemia cell death through a p38 MAP kinase-dependent, NF-kappaB-independent mechanism

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3783575

The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer

26 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2013.114

Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2013.114

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.114

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18 August 2017

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18 August 2017

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