Development and characterization of NEX- Pten, a novel forebrain excitatory neuron-specific knockout mouse. (Q37156089)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22572802%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Development and characterization of NEX- Pten, a novel forebrain excitatory neuron-specific knockout mouse (English)

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1 February 2020

0 references

Gabriella D'Arcangelo

6

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1 February 2020

author name string

Tatiana M Kazdoba

1

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1 February 2020

C Nicole Sunnen

2

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1 February 2020

Beth Crowell

3

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1 February 2020

Gum Hwa Lee

4

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1 February 2020

Anne E Anderson

5

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1 February 2020

publication date

8 May 2012

1 reference

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Developmental Neuroscience

1 February 2020

published in

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volume

34

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1 February 2020

issue

2-3

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1 February 2020

page(s)

198-209

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describes a project that uses

1 February 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3767032/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Inhibition of the mammalian target of rapamycin blocks epilepsy progression in NS-Pten conditional knockout mice

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Phosphatase and tensin homolog (PTEN) gene mutations and autism: literature review and a case report of a patient with Cowden syndrome, autistic disorder, and epilepsy

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Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain

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Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling

6 September 2017

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The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

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Pten knockdown in vivo increases excitatory drive onto dentate granule cells

6 September 2017

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PTEN is recruited to the postsynaptic terminal for NMDA receptor-dependent long-term depression

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Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice

6 September 2017

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Laminar and compartmental regulation of dendritic growth in mature cortex.

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Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities

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Function of PTEN during the formation and maintenance of neuronal circuits in the brain

6 September 2017

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A missed exit: Reelin sets in motion Dab1 polyubiquitination to put the break on neuronal migration

6 September 2017

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Cullin 5 regulates Dab1 protein levels and neuron positioning during cortical development

6 September 2017

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6 September 2017

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Mutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly

6 September 2017

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Pten regulates neuronal arborization and social interaction in mice

6 September 2017

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6 September 2017

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Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations

6 September 2017

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

6 September 2017

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6 September 2017

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Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

6 September 2017

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6 September 2017

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6 September 2017

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

6 September 2017

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6 September 2017

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

6 September 2017

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6 September 2017

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Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia

3 September 2018

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3 September 2018

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Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice.

3 September 2018

1 reference

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Roles of glutamate receptors and the mammalian target of rapamycin (mTOR) signaling pathway in activity-dependent dendritic protein synthesis in hippocampal neurons

3 September 2018

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Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease

3 September 2018

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Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

3 September 2018

1 reference

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Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

3 September 2018

1 reference

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3 September 2018

Identifiers

DOI

10.1159/000337229

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22572802%20AND%20SRC:MED&resulttype=core&format=json

release_iicdxrhemfh6tjzp2mgytabale

1 February 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/iicdxrhemfh6tjzp2mgytabale

mapped directly with Wikidata item

24 November 2022

based on heuristic

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1 February 2020

1 reference

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