Genetic and molecular differences in prostate carcinogenesis between African American and Caucasian American men. (Q37139054)

18 August 2017

1 reference

21 February 2023

Genetic and molecular differences in prostate carcinogenesis between African American and Caucasian American men. (English)

1 reference

18 August 2017

1 reference

21 February 2023

1 reference

30 January 2021

1 reference

1 reference

inferred from abstract

author name string

James Farrell

1

1 reference

18 August 2017

Gyorgy Petrovics

2

1 reference

18 August 2017

David G McLeod

3

1 reference

18 August 2017

Shiv Srivastava

4

1 reference

18 August 2017

language of work or name

English

0 references

publication date

25 July 2013

7 references

International Journal of Molecular Sciences

18 August 2017

3 April 2019

9 August 2019

30 January 2021

29 May 2022

12 February 2023

21 February 2023

7 references

18 August 2017

3 April 2019

9 August 2019

30 January 2021

29 May 2022

12 February 2023

21 February 2023

14

1 reference

18 August 2017

8

1 reference

18 August 2017

15510-15531

1 reference

Creative Commons Attribution 3.0 Unported

18 August 2017

6 references

3 April 2019

9 August 2019

30 January 2021

29 May 2022

12 February 2023

on focus list of Wikimedia project

21 February 2023

copyright status

copyrighted

0 references

ScienceSource

0 references

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Racial disparities in the association between variants on 8q24 and prostate cancer: a systematic review and meta-analysis

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14 September 2017

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Racial/Ethnic patterns in prostate cancer outcomes in an active surveillance cohort

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Minireview: Alternative activation pathways for the androgen receptor in prostate cancer

14 September 2017

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14 September 2017

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The genomic complexity of primary human prostate cancer

14 September 2017

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Genetics of prostate cancer risk

14 September 2017

1 reference

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Analysis of the 10q11 cancer risk locus implicates MSMB and NCOA4 in human prostate tumorigenesis

14 September 2017

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14 September 2017

1 reference

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14 September 2017

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Evidence for geographical and racial variation in serum sex steroid levels in older men.

14 September 2017

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Antibody-based detection of ERG rearrangement-positive prostate cancer

14 September 2017

1 reference

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Copy number and gene expression differences between African American and Caucasian American prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Identification of differentially methylated genes in normal prostate tissues from African American and Caucasian men.

14 September 2017

1 reference

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CYP17 polymorphisms and prostate cancer outcomes

14 September 2017

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Do African American men have lower survival from prostate cancer compared with White men? A meta-analysis

14 September 2017

1 reference

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Effect of dutasteride on the risk of prostate cancer

14 September 2017

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1{alpha},25-Dihydroxyvitamin D3 inhibits growth of VCaP prostate cancer cells despite inducing the growth-promoting TMPRSS2:ERG gene fusion

14 September 2017

1 reference

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Interplay of race, socioeconomic status, and treatment on survival of patients with prostate cancer

14 September 2017

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Aromatase and regulating the estrogen:androgen ratio in the prostate gland.

14 September 2017

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Evaluation of the 8q24 prostate cancer risk locus and MYC expression.

14 September 2017

1 reference

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ETS gene fusions in prostate cancer: from discovery to daily clinical practice

14 September 2017

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Prostate cancer disparities in Black men of African descent: a comparative literature review of prostate cancer burden among Black men in the United States, Caribbean, United Kingdom, and West Africa

14 September 2017

1 reference

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Genetic variants and family history predict prostate cancer similar to prostate-specific antigen

14 September 2017

1 reference

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Prostate cancer genomics: towards a new understanding

14 September 2017

1 reference

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Concepts of epigenetics in prostate cancer development

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Delineation of TMPRSS2-ERG splice variants in prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Genetic susceptibility to prostate cancer in men of African descent: implications for global disparities in incidence and outcomes

14 September 2017

1 reference

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Multiple loci identified in a genome-wide association study of prostate cancer

14 September 2017

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Higher expression of the androgen-regulated gene PSA/HK3 mRNA in prostate cancer tissues predicts biochemical recurrence-free survival

14 September 2017

1 reference

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Genetic polymorphisms in CYP17, CYP3A4, CYP19A1, SRD5A2, IGF-1, and IGFBP-3 and prostate cancer risk in African-American men: the Flint Men's Health Study.

14 September 2017

1 reference

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Non-genomic actions of androgens.

14 September 2017

1 reference

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Expression of the TMPRSS2:ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer

14 September 2017

1 reference

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Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids

14 September 2017

1 reference

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Abnormal DNA methylation, epigenetics, and prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

DNA methylation of GSTP1 as biomarker in diagnosis of prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Operating characteristics of prostate-specific antigen in men with an initial PSA level of 3.0 ng/ml or lower

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Systematic evaluation of genetic variation at the androgen receptor locus and risk of prostate cancer in a multiethnic cohort study

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Molecular biomarker in prostate cancer: the role of CpG island hypermethylation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Absence of a correlation of androgen receptor gene CAG repeat length and prostate cancer risk in an African-American population

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Explaining racial differences in prostate cancer in the United States: sociology or biology?

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Racial differences in androgen receptor protein expression in men with clinically localized prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

The influence of finasteride on the development of prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Empiric risk of prostate carcinoma for relatives of patients with prostate carcinoma: a meta-analysis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Effect of the androgen receptor CAG repeat polymorphism on transcriptional activity: specificity in prostate and non-prostate cell lines

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Serum testosterone levels in African-American and white men undergoing prostate biopsy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Androgen receptor gene CAG repeat length varies in a race-specific fashion in men without prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

The CAG repeat within the androgen receptor gene and its relationship to prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Prospective study of sex hormone levels and risk of prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Serum testosterone levels in healthy young black and white men.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups

14 September 2017

1 reference

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The development of prostatic adenocarcinoma in Nb rats following prolonged sex hormone administration

14 September 2017

1 reference

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TMPRSS2-ERG gene fusion prevalence and class are significantly different in prostate cancer of Caucasian, African-American and Japanese patients

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Evaluation of the ETS-related gene mRNA in urine for the detection of prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Frequency of the TMPRSS2:ERG gene fusion is increased in moderate to poorly differentiated prostate cancers

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

The gene encoding the prostatic tumor suppressor PSP94 is a target for repression by the Polycomb group protein EZH2.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Prostate-specific antigen values at the time of prostate cancer diagnosis in African-American men.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor: possible pathogenetic relevance for the (CAG)n-expanded neuronopathies

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

29 September 2017

MYC and Prostate Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

ERG oncoprotein expression in prostate cancer: clonal progression of ERG-positive tumor cells and potential for ERG-based stratification

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Prostate cancer risk allele specific for African descent associates with pathologic stage at prostatectomy.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

TMPRSS2-ERG fusion is frequently observed in Gleason pattern 3 prostate cancer in a Canadian cohort

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

The effect of race/ethnicity on the accuracy of the 2001 Partin Tables for predicting pathologic stage of localized prostate cancer

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

The androgen receptor CAG and GGN repeat polymorphisms and prostate cancer susceptibility in African-American men: results from the Flint Men's Health Study

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Multiple regions within 8q24 independently affect risk for prostate cancer

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

A common variant associated with prostate cancer in European and African populations

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Hypermethylation of the human glutathione S-transferase-pi gene (GSTP1) CpG island is present in a subset of proliferative inflammatory atrophy lesions but not in normal or hyperplastic epithelium of the prostate: a detailed study using laser-captur

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Association of prostate cancer risk with genetic polymorphisms in vitamin D receptor and androgen receptor

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Induction at high incidence of ductal prostate adenocarcinomas in NBL/Cr and Sprague-Dawley Hsd:SD rats treated with a combination of testosterone and estradiol-17 beta or diethylstilbestrol.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Serum testosterone and dihydrotestosterone in carcinoma of the prostate

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

8q24 amplification is associated with Myc expression and prostate cancer progression and is an independent predictor of recurrence after radical prostatectomy

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Prostate cancer diagnosis among men with isolated high-grade intraepithelial neoplasia enrolled onto a 3-year prospective phase III clinical trial of oral toremifene

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Fish intake, cooking practices, and risk of prostate cancer: results from a multi-ethnic case-control study

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Prostate biopsies from black men express higher levels of aggressive disease biomarkers than prostate biopsies from white men.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Chromosome 8 markers of metastatic prostate cancer in African American men: gain of the MIR151 gene and loss of the NKX3-1 gene

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Tumor immunobiological differences in prostate cancer between African-American and European-American men.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Endogenous sex hormones and prostate cancer: a collaborative analysis of 18 prospective studies

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Serum estrogen, but not testosterone, levels differ between black and white men in a nationally representative sample of Americans

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Differences in clinicopathologic features of prostate cancer between black and white patients treated in the 1990s and 2000s.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

The impact of CAG repeats in exon 1 of the androgen receptor on disease progression after prostatectomy

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Pretreatment total testosterone level predicts pathological stage in patients with localized prostate cancer treated with radical prostatectomy

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Associations of serum testosterone with microvessel density, androgen receptor density and androgen receptor gene polymorphism in prostate cancer

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Racial variation in CAG repeat lengths within the androgen receptor gene among prostate cancer patients of lower socioeconomic status

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

Testosterone, sex hormone-binding globulin, and body composition in young adult African American and Caucasian men.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759870

3 September 2018

1 reference

12 December 2020

Prostatic tissue testosterone and dihydrotestosterone in African-American and white men

1 reference

12 December 2020

Significant associations of prostate cancer susceptibility variants with survival in patients treated with androgen-deprivation therapy

1 reference

12 December 2020

Racial differences in serum prostate-specific antigen (PSA) doubling time, histopathological variables and long-term PSA recurrence between African-American and white American men undergoing radical prostatectomy for clinically localized prostate ca

1 reference

12 December 2020

Toremifene for the prevention of prostate cancer in men with high grade prostatic intraepithelial neoplasia: results of a double-blind, placebo controlled, phase IIB clinical trial

1 reference

12 December 2020

Cumulative association of five genetic variants with prostate cancer

1 reference

12 December 2020

Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA

1 reference

12 December 2020

Is the androgen receptor CAG repeat length significant for prostate cancer?

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS140815510

1 reference

18 August 2017

1 reference

18 August 2017

1 reference