Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice (Q37052491)

17 August 2017

Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice (English)

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17 August 2017

1 reference

Lisiane B Meira

1

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17 August 2017

Catherine A Moroski-Erkul

2

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17 August 2017

Stephanie L Green

3

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17 August 2017

Jennifer A Calvo

4

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17 August 2017

Roderick T Bronson

5

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17 August 2017

Dharini Shah

6

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17 August 2017

Leona D Samson

7

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17 August 2017

language of work or name

English

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publication date

12 January 2009

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17 August 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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17 August 2017

106

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17 August 2017

3

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17 August 2017

888-893

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DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

17 August 2017

1 reference

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Targeting human 8-oxoguanine DNA glycosylase (hOGG1) to mitochondria enhances cisplatin cytotoxicity in hepatoma cells

29 September 2017

1 reference

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Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome

29 September 2017

1 reference

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Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Retinal degeneration and ionizing radiation hypersensitivity in a mouse model for Cockayne syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

State of the art. Chronic obstructive pulmonary disease, inflammation, and lung cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Antioxidants reduce cone cell death in a model of retinitis pigmentosa

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Organ and cell specificity of base excision repair mutants in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Photoreceptor cell apoptosis induced by the 2-nitroimidazole radiosensitizer, CI-1010, is mediated by p53-linked activation of caspase-3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Oxanine DNA glycosylase activity from Mammalian alkyladenine glycosylase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

New immunoaffinity-LC-MS/MS methodology reveals that Aag null mice are deficient in their ability to clear 1,N6-etheno-deoxyadenosine DNA lesions from lung and liver in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

CI-1010 induced opening of the mitochondrial permeability transition pore precedes oxidative stress and apoptosis in SY5Y neuroblastoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Deregulated DNA polymerase beta induces chromosome instability and tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

3-methyladenine DNA glycosylases: structure, function, and biological importance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

DNA adduct formation from tobacco-specific N-nitrosamines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Generation of a strong mutator phenotype in yeast by imbalanced base excision repair

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Photoreceptor apoptosis induced by a single systemic administration of N-methyl-N-nitrosourea in the rat retina

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Ubiquitination-dependent proteolysis of O6-methylguanine-DNA methyltransferase in human and murine tumor cells following inactivation with O6-benzylguanine or 1,3-bis(2-chloroethyl)-1-nitrosourea

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Cell fate determination in the vertebrate retina

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

In vivo evidence for endogenous DNA alkylation damage as a source of spontaneous mutation in eukaryotic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Efficient selection for high-expression transfectants with a novel eukaryotic vector

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Evaluation of oxidative processes in human pigment epithelial cells associated with retinal outer segment phagocytosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

DNA damage and repair in light-induced photoreceptor degeneration.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

3-Methyladenine DNA glycosylase-deficient Aag null mice display unexpected bone marrow alkylation resistance

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2621254

Oxidative stress induces caspase-independent retinal apoptosis in vitro

4 September 2018

1 reference

12 December 2020

Retinal degeneration in the mouse. A model induced transplacentally by methylnitrosourea

1 reference

12 December 2020

Retinal degeneration induced by N-methyl-N-nitrosourea and detection of 7-methyldeoxyguanosine in the rat retina

1 reference

12 December 2020

Phagocytosis and H2O2 induce catalase and metallothionein gene expression in human retinal pigment epithelial cells

1 reference

12 December 2020

N-methyl-N-nitrosourea-induced photoreceptor apoptosis in the mouse retina

1 reference

12 December 2020

Multipotential stem cells and progenitors in the vertebrate retina

1 reference

12 December 2020

Retinal degeneration induced by N-methyl-N-nitrosourea in Syrian golden hamsters

1 reference

12 December 2020

DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents

1 reference

12 December 2020

Enhanced expression and activity of DNA polymerase beta in chronic myelogenous leukemia

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0807030106

1 reference

17 August 2017

0 references

1 reference

17 August 2017

PubMed publication ID

19139400

1 reference