Recql5 plays an important role in DNA replication and cell survival after camptothecin treatment (Q37035110)

17 August 2017

Recql5 plays an important role in DNA replication and cell survival after camptothecin treatment (English)

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17 August 2017

Yiduo Hu

1

1 reference

17 August 2017

Xincheng Lu

2

1 reference

17 August 2017

Guangjin Zhou

3

1 reference

17 August 2017

Ellen L Barnes

4

1 reference

17 August 2017

Guangbin Luo

5

1 reference

17 August 2017

5 November 2008

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17 August 2017

10

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Molecular Biology of the Cell

inferred from page(s)

published in

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17 August 2017

20

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17 August 2017

1

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17 August 2017

114-123

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describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2613109/fullTextXML

inferred from PubMed Central ID database lookup

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RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments

29 September 2017

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The intra-S-phase checkpoint affects both DNA replication initiation and elongation: single-cell and -DNA fiber analyses

29 September 2017

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Arrested replication fork processing: interplay between checkpoints and recombination

29 September 2017

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Human RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork

29 September 2017

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Repair of topoisomerase I-mediated DNA damage

29 September 2017

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Roles of the Bloom's syndrome helicase in the maintenance of genome stability

29 September 2017

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Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage

29 September 2017

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Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks

29 September 2017

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Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

29 September 2017

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Recql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers

29 September 2017

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29 September 2017

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

29 September 2017

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Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome

29 September 2017

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The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

29 September 2017

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Chk1-dependent S-M checkpoint delay in vertebrate cells is linked to maintenance of viable replication structures.

29 September 2017

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Poly(ADP-ribose) polymerase inhibitors as potential chemotherapeutic agents

29 September 2017

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Genetic steps of mammalian homologous repair with distinct mutagenic consequences

29 September 2017

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Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide

29 September 2017

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DNA repair functions that control sensitivity to topoisomerase-targeting drugs

29 September 2017

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Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

29 September 2017

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29 September 2017

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RecQ helicases: caretakers of the genome

29 September 2017

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Analysis of helicase activity and substrate specificity of Drosophila RECQ5

29 September 2017

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RecQ family helicases: roles as tumor suppressor proteins

29 September 2017

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Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells

29 September 2017

1 reference

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Participation of recombination proteins in rescue of arrested replication forks in UV-irradiated Escherichia coli need not involve recombination

29 September 2017

1 reference

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Characterization of homologous recombination induced by replication inhibition in mammalian cells

29 September 2017

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DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells

29 September 2017

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Molecular and biological determinants of the cytotoxic actions of camptothecins. Perspective for the development of new topoisomerase I inhibitors

29 September 2017

1 reference

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RAD51 supports spontaneous non-homologous recombination in mammalian cells, but not the corresponding process induced by topoisomerase inhibitors

29 September 2017

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Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

29 September 2017

1 reference

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Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms.

29 September 2017

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Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613109

Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

29 September 2017

1 reference

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Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase

29 September 2017

1 reference

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Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613109

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613109

An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613109

Positional cloning of the Werner's syndrome gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613109

The Bloom's syndrome gene product is homologous to RecQ helicases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613109

Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613109

The U.V. sensitivity of bacteria: its relation to the DNA replication cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613109

Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613109

DNA-break repair, radioresistance of DNA synthesis, and camptothecin sensitivity in the radiation-sensitive irs mutants: comparisons to ataxia-telangiectasia cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613109

Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613109

Inactivation of homologous recombination suppresses defects in topoisomerase III-deficient mutants

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613109

Transcriptional regulation of mitotic genes by camptothecin-induced DNA damage: microarray analysis of dose- and time-dependent effects.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613109

Cloning, genomic structure and chromosomal localization of the gene encoding mouse DNA helicase RECQL5beta.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613109

RecQ and RecJ process blocked replication forks prior to the resumption of replication in UV-irradiated Escherichia coli

4 September 2018

1 reference

12 December 2020

Antitumour drugs impede DNA uncoiling by topoisomerase I

1 reference

12 December 2020

Effects of inhibitors of DNA synthesis on spontaneous and ultraviolet light-induced sister-chromatid exchanges in Chinese hamster cells

1 reference

12 December 2020

Sensitivity of Bloom syndrome fibroblasts to mitomycin C

1 reference

12 December 2020

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E08-06-0565

1 reference

17 August 2017

1 reference

17 August 2017

1 reference