Identification of a Paralog-Specific Notch1 Intracellular Domain Degron (Q36957912)

17 August 2017

Identification of a Paralog-Specific Notch1 Intracellular Domain Degron (English)

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17 August 2017

Matthew R Broadus

1

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17 August 2017

Tony W Chen

2

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17 August 2017

Leif R Neitzel

3

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17 August 2017

Victoria H Ng

4

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17 August 2017

Jeanne N Jodoin

5

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17 August 2017

Laura A Lee

6

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17 August 2017

Adrian Salic

7

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17 August 2017

David J Robbins

8

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17 August 2017

Anthony J Capobianco

9

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17 August 2017

James G Patton

10

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17 August 2017

Stacey S Huppert

11

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17 August 2017

Ethan Lee

12

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17 August 2017

18 May 2016

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17 August 2017

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17 August 2017

15

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17 August 2017

9

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17 August 2017

1920-1929

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describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4889555/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Reconstitution Of β-catenin degradation in Xenopus egg extract

1 reference

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The extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney development

29 September 2017

1 reference

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Mechanisms and function of substrate recruitment by F-box proteins.

29 September 2017

1 reference

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Ubiquitinations in the notch signaling pathway.

29 September 2017

1 reference

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Oscillatory links of Fgf signaling and Hes7 in the segmentation clock

29 September 2017

1 reference

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Real-time imaging of notch activation with a luciferase complementation-based reporter.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

Assembly of a Notch transcriptional activation complex requires multimerization

29 September 2017

1 reference

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Mechanistic insights into Notch receptor signaling from structural and biochemical studies

29 September 2017

1 reference

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Notch signaling, the segmentation clock, and the patterning of vertebrate somites

29 September 2017

1 reference

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The canonical Notch signaling pathway: unfolding the activation mechanism

29 September 2017

1 reference

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FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

29 September 2017

1 reference

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The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

29 September 2017

1 reference

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Integrin-linked kinase controls Notch1 signaling by down-regulation of protein stability through Fbw7 ubiquitin ligase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

29 September 2017

1 reference

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

29 September 2017

1 reference

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Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

Notch signaling: cell fate control and signal integration in development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

Juxtacrine signaling is inherently noisy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

Fluorescent protein expression driven by her4 regulatory elements reveals the spatiotemporal pattern of Notch signaling in the nervous system of zebrafish embryos

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

Evidence that C promoter-binding factor 1 binding is required for Notch-1-mediated repression of activator protein-1.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

Multiple regulatory elements with spatially and temporally distinct activities control neurogenin1 expression in primary neurons of the zebrafish embryo.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889555

Acetylation controls Notch3 stability and function in T-cell leukemia

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27210761

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELREP.2016.04.070

1 reference

17 August 2017

1 reference

17 August 2017

1 reference