Improved insulin sensitivity despite increased visceral adiposity in mice deficient for the immune cell transcription factor T-bet (Q36938197)

17 August 2017

Improved insulin sensitivity despite increased visceral adiposity in mice deficient for the immune cell transcription factor T-bet (English)

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17 August 2017

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Emilie Stolarczyk

1

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17 August 2017

Chi Teng Vong

2

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17 August 2017

Esperanza Perucha

3

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17 August 2017

Ian Jackson

4

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17 August 2017

Michael A Cawthorne

5

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17 August 2017

Edward T Wargent

6

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17 August 2017

Nick Powell

7

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17 August 2017

James B Canavan

8

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17 August 2017

Graham M Lord

9

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17 August 2017

Jane K Howard

10

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17 August 2017

1 April 2013

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17 August 2017

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17 August 2017

17

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17 August 2017

4

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17 August 2017

520-533

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describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3685808/fullTextXML

inferred from PubMed Central ID database lookup

cites work

T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements.

1 reference

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The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells.

29 September 2017

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The cellular and signaling networks linking the immune system and metabolism in disease

29 September 2017

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Systemic inflammation and insulin sensitivity in obese IFN-γ knockout mice

29 September 2017

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Genetic visualization of the secondary olfactory pathway in Tbx21 transgenic mice

29 September 2017

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B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

29 September 2017

1 reference

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The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes

29 September 2017

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Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells

29 September 2017

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CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

29 September 2017

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Normalization of obesity-associated insulin resistance through immunotherapy

29 September 2017

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Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

29 September 2017

1 reference

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CD4 T cells: fates, functions, and faults

29 September 2017

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Genetically programmed biases in Th1 and Th2 immune responses modulate atherogenesis

29 September 2017

1 reference

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Beneficial effects of subcutaneous fat transplantation on metabolism

29 September 2017

1 reference

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Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system

29 September 2017

1 reference

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Obesity-associated improvements in metabolic profile through expansion of adipose tissue

29 September 2017

1 reference

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The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease

29 September 2017

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Adipose tissues as an ancestral immune organ: site-specific change in obesity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

New methods for calculating metabolic rate with special reference to protein metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

29 September 2017

1 reference

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Obesity is associated with macrophage accumulation in adipose tissue

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Innate and adaptive immunity in the pathogenesis of atherosclerosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Developmental expression of the T-box transcription factor T-bet/Tbx21 during mouse embryogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

A novel transcription factor, T-bet, directs Th1 lineage commitment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Evolution of developmental functions by the Eomesodermin, T-brain-1, Tbx21 subfamily of T-box genes: insights from amphioxus

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Deficiency in interferon-gamma results in reduced body weight and better glucose tolerance in mice

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Monocytes control natural killer cell differentiation to effector phenotypes

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Unexpected trafficking of immune cells within the adipose tissue during the onset of obesity

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Prevention of diet-induced obesity and impaired glucose tolerance in rats following administration of leptin to their mothers.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

T-ing up inflammation in fat

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685808

T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance

4 December 2018

1 reference

12 December 2020

Insulin resistance associated to obesity: the link TNF-alpha

1 reference

12 December 2020

Metabolically healthy but obese individuals

1 reference

12 December 2020

Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities☆

1 reference

12 December 2020

10.1016/J.CMET.2013.02.019

Identifiers

DOI

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

23562076

1 reference