Long-term multilineage engraftment of autologous genome-edited hematopoietic stem cells in nonhuman primates (Q36920437)

17 August 2017

Long-term multilineage engraftment of autologous genome-edited hematopoietic stem cells in nonhuman primates (English)

1 reference

17 August 2017

11

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1 June 2020

13

Hans-Peter Kiem

1 reference

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1 June 2020

10

Edward J Rebar

1 reference

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1 June 2020

author name string

Christopher W Peterson

1

1 reference

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1 June 2020

Jianbin Wang

2

1 reference

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1 June 2020

Krystin K Norman

3

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1 June 2020

Zachary K Norgaard

4

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1 June 2020

Olivier Humbert

5

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1 June 2020

Collette K Tse

6

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1 June 2020

Jenny J Yan

7

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1 June 2020

Richard G Trimble

8

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1 June 2020

David A Shivak

9

1 reference

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1 June 2020

Michael C Holmes

12

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1 June 2020

language of work or name

English

0 references

publication date

15 March 2016

1 reference

17 August 2017

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1 June 2020

volume

127

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1 June 2020

issue

20

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1 June 2020

page(s)

2416-2426

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Multilineage polyclonal engraftment of Cal-1 gene-modified cells and in vivo selection after SHIV infection in a nonhuman primate model of AIDS

1 June 2020

cites work

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Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors.

29 September 2017

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Pigtailed macaques as a model to study long-term safety of lentivirus vector-mediated gene therapy for hemoglobinopathies

29 September 2017

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Outcomes following gene therapy in patients with severe Wiskott-Aldrich syndrome

29 September 2017

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Foamy viral vector integration sites in SCID-repopulating cells after MGMTP140K-mediated in vivo selection

29 September 2017

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Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells

29 September 2017

1 reference

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Lentivirus-mediated Gene Transfer in Hematopoietic Stem Cells Is Impaired in SHIV-infected, ART-treated Nonhuman Primates

29 September 2017

1 reference

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Quantifying on- and off-target genome editing

29 September 2017

1 reference

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Severe combined immunodeficiency: recent developments and guidance on clinical management

29 September 2017

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Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9

29 September 2017

1 reference

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Cell-Mediated Immunity to AAV Vectors, Evolving Concepts and Potential Solutions

29 September 2017

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Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV

29 September 2017

1 reference

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Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity

29 September 2017

1 reference

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Disorders of neutrophil function: an overview

29 September 2017

1 reference

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General considerations on the biosafety of virus-derived vectors used in gene therapy and vaccination

29 September 2017

1 reference

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Pre-clinical modeling of CCR5 knockout in human hematopoietic stem cells by zinc finger nucleases using humanized mice

29 September 2017

1 reference

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Recent advances in understanding and managing adenosine deaminase and purine nucleoside phosphorylase deficiencies

29 September 2017

1 reference

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Considerations in the development of nonhuman primate models of combination antiretroviral therapy for studies of AIDS virus suppression, residual virus, and curative strategies

29 September 2017

1 reference

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Nonhuman primate models in AIDS research

29 September 2017

1 reference

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Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases

29 September 2017

1 reference

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Gene therapy for PIDs: progress, pitfalls and prospects

29 September 2017

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Combinatorial anti-HIV gene therapy: using a multipronged approach to reach beyond HAART

29 September 2017

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Extended survival of glioblastoma patients after chemoprotective HSC gene therapy

29 September 2017

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Hematopoietic stem cell expansion facilitates multilineage engraftment in a nonhuman primate cord blood transplantation model.

29 September 2017

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Genome editing with engineered zinc finger nucleases

29 September 2017

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Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

29 September 2017

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Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates.

29 September 2017

1 reference

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Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

29 September 2017

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Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy

29 September 2017

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29 September 2017

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Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

29 September 2017

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Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression

29 September 2017

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Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors

29 September 2017

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Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy

29 September 2017

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Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

29 September 2017

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Highly efficient endogenous human gene correction using designed zinc-finger nucleases

29 September 2017

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Gene therapy in nonhuman primate models of human autoimmune disease.

29 September 2017

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Highly efficient gene transfer into baboon marrow repopulating cells using GALV-pseudotype oncoretroviral vectors produced by human packaging cells

29 September 2017

1 reference

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Targeted genome editing in human repopulating haematopoietic stem cells

29 September 2017

1 reference

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Gene delivery improvement for treating the lysosomal storage disorder metachromatic leukodystrophy

27 June 2018

1 reference

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Site-specific integration and tailoring of cassette design for sustainable gene transfer.

4 September 2018

1 reference

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Transient cold shock enhances zinc-finger nuclease-mediated gene disruption.

4 September 2018

1 reference

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Dopamine gene therapy for Parkinson's disease in a nonhuman primate without associated dyskinesia.

4 September 2018

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Targeted gene addition to human mesenchymal stromal cells as a cell-based plasma-soluble protein delivery platform.

4 September 2018

1 reference

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Impact of Delta 32-CCR5 heterozygosity on HIV-1 genetic evolution and variability--a study of 4 individuals infected with closely related HIV-1 strains

4 September 2018

1 reference

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Safe harbours for the integration of new DNA in the human genome

4 September 2018

1 reference

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10.1182/BLOOD-2015-09-672337

4 December 2018

Identifiers

DOI

1 reference

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1 June 2020

1 reference

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1 June 2020

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