The transforming mutation E17K/AKT1 is not a major event in B-cell-derived lymphoid leukaemias. (Q36858031)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18665177%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

title

The transforming mutation E17K/AKT1 is not a major event in B-cell-derived lymphoid leukaemias (English)

1 reference

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11 January 2020

1 reference

1

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11 January 2020

Maher Sughayer

2

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11 January 2020

author name string

H A Mohammad

3

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11 January 2020

A S Awidi

4

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11 January 2020

M S EL-Khateeb

5

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11 January 2020

S I Ismail

6

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11 January 2020

language of work or name

English

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publication date

1 August 2008

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British Journal of Cancer

11 January 2020

published in

1 reference

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11 January 2020

volume

99

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11 January 2020

issue

3

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11 January 2020

page(s)

488-490

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https://scigraph.springernature.com/pub.10.1038/sj.bjc.6604512

11 January 2020

exact match

0 references

cites work

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Activating E17K mutation in the gene encoding the protein kinase AKT1 in a subset of squamous cell carcinoma of the lung

29 September 2017

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Genetic alteration associated with chronic lymphocytic leukemia

29 September 2017

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The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells

29 September 2017

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Pathology of chronic lymphocytic leukemia: an update

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A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

29 September 2017

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Akt-dependent transformation: there is more to growth than just surviving

29 September 2017

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Activation of AKT kinases in cancer: implications for therapeutic targeting

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Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells.

29 September 2017

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A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells.

29 September 2017

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Akt stimulates aerobic glycolysis in cancer cells

29 September 2017

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Structure, regulation and function of PKB/AKT--a major therapeutic target

29 September 2017

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The protein kinase B/Akt signalling pathway in human malignancy

29 September 2017

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AKT plays a central role in tumorigenesis

29 September 2017

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Thymic lymphoma induction by the AKT8 murine retrovirus

29 September 2017

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Clinical staging of chronic lymphocytic leukemia

29 September 2017

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Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma

29 September 2017

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PI3K/AKT pathway activation in acute myeloid leukaemias is not associated with AKT1 pleckstrin homology domain mutation

29 September 2017

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Regulation of Akt/PKB by phosphatidylinositol 3-kinase-dependent and -independent pathways in B-cell chronic lymphocytic leukemia cells: role of protein kinase C{beta}.

27 June 2018

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The role of Aktand RAFTK in beta1 integrin mediated survival of precursor B-acute lymphoblastic leukemia cells

27 June 2018

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Involvement of protein kinase C and phosphatidylinositol 3-kinase pathways in the survival of B-cell chronic lymphocytic leukemia cells.

27 June 2018

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Absence of mutations in the AKT1 oncogene in glioblastomas and medulloblastomas.

27 June 2018

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The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease.

4 September 2018

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Stromal cell protection of B-lineage acute lymphoblastic leukemic cells during chemotherapy requires active Akt.

4 September 2018

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Mutational analysis of AKT1, AKT2 and AKT3 genes in common human carcinomas

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18665177

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chronic lymphocytic leukaemia and acute myeloid leukaemia are not associated with AKT1 pleckstrin homology domain (E17K) mutations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18665177

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.BJC.6604512

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18665177%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18665177%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference