Plasma membrane localization signals in the light chain of botulinum neurotoxin (Q36854737)

16 August 2017

Plasma membrane localization signals in the light chain of botulinum neurotoxin (English)

1 reference

16 August 2017

Ester Fernández-Salas

1

1 reference

16 August 2017

Lance E Steward

2

1 reference

16 August 2017

Helen Ho

3

1 reference

16 August 2017

Patton E Garay

4

1 reference

16 August 2017

Sarah W Sun

5

1 reference

16 August 2017

Marcella A Gilmore

6

1 reference

16 August 2017

Joseph V Ordas

7

1 reference

16 August 2017

Joanne Wang

8

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16 August 2017

Joseph Francis

9

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16 August 2017

K Roger Aoki

10

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16 August 2017

language of work or name

English

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publication date

24 February 2004

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Proceedings of the National Academy of Sciences of the United States of America

16 August 2017

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16 August 2017

101

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16 August 2017

3208-3213

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16 August 2017

9

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Evaluation of the therapeutic usefulness of botulinum neurotoxin B, C1, E, and F compared with the long lasting type A. Basis for distinct durations of inhibition of exocytosis in central neurons

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Snares and Munc18 in synaptic vesicle fusion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Genetic analyses of adaptin function from yeast to mammals.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Identification of an axonal determinant in the C-terminus of the sodium channel Na(v)1.2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

The Di-leucine motif of vesicle-associated membrane protein 4 is required for its localization and AP-1 binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Clostridium botulinum and its neurotoxins: a metabolic and cellular perspective

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Other noncosmetic uses of BOTOX.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Moving the insulin-regulated glucose transporter GLUT4 into and out of storage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Identification of the characteristics that underlie botulinum toxin potency: implications for designing novel drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

How botulinum and tetanus neurotoxins block neurotransmitter release.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Neurotoxins affecting neuroexocytosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Adaptors for clathrin-mediated traffic

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Di-leucine signals mediate targeting of tyrosinase and synaptotagmin to synaptic-like microvesicles within PC12 cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Membrane trafficking of neurotransmitter transporters in the regulation of synaptic transmission

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Crystal structure of botulinum neurotoxin type A and implications for toxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Acidic di-leucine motif essential for AP-3-dependent sorting and restriction of the functional specificity of the Vam3p vacuolar t-SNARE.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Transient expression of botulinum neurotoxin C1 light chain differentially inhibits calcium and glucose induced insulin secretion in clonal beta-cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

The N-end rule: functions, mysteries, uses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Proteolysis of SNAP-25 by types E and A botulinal neurotoxins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

The residues Leu(Ile)475-Ile(Leu, Val, Ala)476, contained in the extended carboxyl cytoplasmic tail, are critical for targeting of the resident lysosomal membrane protein LIMP II to lysosomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

A single internalization signal from the di-leucine family is critical for constitutive endocytosis of the type II TGF-beta receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Cloning, expression, and one-step purification of the minimal essential domain of the light chain of botulinum neurotoxin type A.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Role of tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP) in vesicular transport mediating neurite outgrowth.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Sequence homology and structural analysis of the clostridial neurotoxins

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Identification of an insulin-responsive, slow endocytic recycling mechanism in Chinese hamster ovary cells.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

A leucine-based motif mediates the endocytosis of vesicular monoamine and acetylcholine transporters

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Botulinum neurotoxin B inhibits insulin-stimulated glucose uptake into 3T3-L1 adipocytes and cleaves cellubrevin unlike type A toxin which failed to proteolyze the SNAP-23 present

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365768

Persistence of botulinum neurotoxin A demonstrated by sequential administration of serotypes A and E in rat EDL muscle

27 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400229101

Different time courses of recovery after poisoning with botulinum neurotoxin serotypes A and E in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400229101

Translocation of botulinum neurotoxin light chain protease through the heavy chain channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400229101

Phosphorylation of human gp130 at Ser-782 adjacent to the Di-leucine internalization motif. Effects on expression and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400229101

An evolutionarily conserved dileucine motif in Shal K+ channels mediates dendritic targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400229101

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400229101

Dynamics of motor nerve terminal remodeling unveiled using SNARE-cleaving botulinum toxins: the extent and duration are dictated by the sites of SNAP-25 truncation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400229101

Correlation of cleavage of SNAP-25 with muscle function in a rat model of Botulinum neurotoxin type A induced paralysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400229101

Persistence of botulinum neurotoxin action in cultured spinal cord cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400229101

Botulinum neurotoxin serotypes A and B preparations have different safety margins in preclinical models of muscle weakening efficacy and systemic safety

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400229101

The cytoplasmic tail of the vesicular acetylcholine transporter contains a synaptic vesicle targeting signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400229101

Systematic mutational analysis of the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor cytoplasmic domain. An acidic cluster containing a key aspartate is important for function in lysosomal enzyme sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400229101

21 January 2018

Identifiers

DOI

10.1073/PNAS.0400229101

1 reference

16 August 2017

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1 reference

16 August 2017

1 reference