Human tumor p53 mutations are selected for in mouse embryonic fibroblasts harboring a humanized p53 gene (Q36853109)

16 August 2017

Human tumor p53 mutations are selected for in mouse embryonic fibroblasts harboring a humanized p53 gene (English)

1 reference

16 August 2017

Zhipei Liu

1

1 reference

16 August 2017

Manfred Hergenhahn

2

1 reference

16 August 2017

Heinz H Schmeiser

3

1 reference

16 August 2017

Gerald N Wogan

4

1 reference

16 August 2017

Amanda Hong

5

1 reference

16 August 2017

Monica Hollstein

6

1 reference

16 August 2017

language of work or name

English

0 references

publication date

19 February 2004

1 reference

Proceedings of the National Academy of Sciences of the United States of America

16 August 2017

1 reference

16 August 2017

101

1 reference

16 August 2017

2963-2968

1 reference

16 August 2017

9

1 reference

The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrity

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Mouse models with modified p53 sequences to study cancer and ageing.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Subpathways of nucleotide excision repair and their regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Aristolochic acid as a probable human cancer hazard in herbal remedies: a review.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Modelling the molecular circuitry of cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

29 September 2017

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

The yeast p53 functional assay: a new tool for molecular epidemiology. Hopes and facts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

p53 and human cancer: the first ten thousand mutations.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Cytochrome P450 and the individuality of species

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Induction of mutations in transgenic animal models: BigBlue and Muta Mouse

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

UV-induced mutagenesis of human p53 in a vector replicated in Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Detection and classification of mutagens: a set of base-specific Salmonella tester strains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Database of p53 gene somatic mutations in human tumors and cell lines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

p53 mutations in human cancers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

In vitro mutational spectrum of aflatoxin B1 in the human hypoxanthine guanine phosphoribosyltransferase gene.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

DNA adducts and p53 mutations in a patient with aristolochic acid-associated nephropathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Sunlight induces pyrimidine dimers preferentially at 5-methylcytosine bases.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Sunlight and the onset of skin cancer

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Deletions and insertions in the p53 tumor suppressor gene in human cancers: confirmation of the DNA polymerase slippage/misalignment model.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Aristolochic acid activates ras genes in rat tumors at deoxyadenosine residues.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

From gene to carcinogen: a rapidly evolving field in molecular epidemiology

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

The IARC TP53 database: new online mutation analysis and recommendations to users

27 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

Simulated sunlight and benzo[a]pyrene diol epoxide induced mutagenesis in the human p53 gene evaluated by the yeast functional assay: lack of correspondence to tumor mutation spectra

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi)

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

Mutagenicity of aristolochic acid in the lambda/lacZ transgenic mouse (MutaMouse).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

Comparison of the genotoxic activities of the K-region dihydrodiol of benzo[a]pyrene with benzo[a]pyrene in mammalian cells: morphological cell transformation; DNA damage; and stable covalent DNA adducts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

Interaction of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) with induced adipocyte differentiation in mouse embryonic fibroblasts (MEFs) involves tyrosine kinase c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

Mining databases for cytochrome P450 genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

Fidelity of uracil-initiated base excision DNA repair in DNA polymerase beta-proficient and -deficient mouse embryonic fibroblast cell extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

Unusual profile and high prevalence of p53 mutations in esophageal squamous cell carcinomas from northern Iran.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

The distribution of UV photoproducts along the human p53 gene and its relation to mutations in skin cancer.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365728

Carcinogens induce targeted mutations in Escherichia coli

4 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

Screening patients for heterozygous p53 mutations using a functional assay in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

The yeast p53 functional assay: a new tool for molecular epidemiology. Hopes and facts

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

32P-post-labelling analysis of DNA adducts formed by aristolochic acid in tissues from patients with Chinese herbs nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

Cooperativity of p19ARF, Mdm2, and p53 in murine tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308607101

Use of a novel real-time quantitative reverse transcription-polymerase chain reaction method to study the effects of cytokines on cytochrome P450 mRNA expression in mouse liver

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14976251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Molecular epidemiology of human cancer: contribution of mutation spectra studies of tumor suppressor genes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14976251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0308607101

1 reference

16 August 2017

0 references

1 reference

16 August 2017

1 reference