Crystal structure of the complex between thrombin and the central "E" region of fibrin (Q36851953)

16 August 2017

Crystal structure of the complex between thrombin and the central "E" region of fibrin (English)

1 reference

16 August 2017

Igor Pechik

1

1 reference

16 August 2017

Joel Madrazo

2

1 reference

16 August 2017

Michael W Mosesson

3

1 reference

16 August 2017

Irene Hernandez

4

1 reference

16 August 2017

Gary L Gilliland

5

1 reference

16 August 2017

Leonid Medved

6

1 reference

16 August 2017

language of work or name

English

0 references

publication date

20 February 2004

1 reference

Proceedings of the National Academy of Sciences of the United States of America

16 August 2017

1 reference

16 August 2017

101

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16 August 2017

2718-2723

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16 August 2017

9

1 reference

SHELXL: high-resolution refinement

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Crystal structure of native chicken fibrinogen at 2.7 A resolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Crystal structure of the central region of bovine fibrinogen (E5 fragment) at 1.4-A resolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The structure and function of the alpha C domains of fibrinogen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The finer things in X-ray diffraction data collection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Detecting and overcoming crystal twinning

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Crystal structure of a 30 kDa C-terminal fragment from the gamma chain of human fibrinogen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Fibrinogen and fibrin--proteins with complex roles in hemostasis and thrombosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Strategy for recombinant multichain protein synthesis: fibrinogen B beta-chain variants as thrombin substrates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The fibrinogen sequences that interact with thrombin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Thrombin interactions with fibrinogen and fibrin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

A model for the specificity of fibrinogen cleavage by thrombin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Spatial structure of thrombin as a guide to its multiple sites of interaction.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Fibrinogen degradation by hementin, a fibrinogenolytic anticoagulant from the salivary glands of the leech Haementeria ghilianii

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

29 September 2017

Fibrinogen and fibrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

High-resolution NMR studies of fibrinogen-like peptides in solution: interaction of thrombin with residues 1-23 of the A alpha chain of human fibrinogen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Fibrin monomer protects thrombin from inactivation by heparin-antithrombin III: implications for heparin efficacy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The structure of a complex of recombinant hirudin and human alpha-thrombin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Molecular basis of fibrinogen Naples associated with defective thrombin binding and thrombophilia. Homozygous substitution of B beta 68 Ala----Thr

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The interaction of thrombin with fibrinogen. A structural basis for its specificity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The structure of residues 7-16 of the A alpha-chain of human fibrinogen bound to bovine thrombin at 2.3-A resolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Fibrinogen ""New York"--an abnormal fibrinogen associated with thromboembolism: functional evaluation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Functional mapping of the surface residues of human thrombin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Complex formation between thrombin and thrombomodulin inhibits both thrombin-catalyzed fibrin formation and factor V activation.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Inhibited thrombins. Interactions with fibrinogen and fibrin

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Fibrinogen assembly and crosslinking on a fibrin fragment E template.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Analysis of fibrinogen alpha residues 27-50: interactions with thrombin

4 September 2018

1 reference

12 December 2020

Identification and characterization of the thrombin binding sites on fibrin

1 reference

12 December 2020

Characterization of fibrinogen New York 1. A dysfunctional fibrinogen with a deletion of B beta(9-72) corresponding exactly to exon 2 of the gene

1 reference

12 December 2020

Thrombin activity of fibrin thrombi and soluble plasmic derivatives

1 reference

12 December 2020

A role for platelets and thrombin in the juvenile stroke of two siblings with defective thrombin-adsorbing capacity of fibrin(ogen)

1 reference

12 December 2020

Studies on the mechanism of thrombin. Interaction with fibrin

1 reference

12 December 2020

The polymerization and thrombin-binding properties of des-(B beta 1-42)-fibrin

1 reference

12 December 2020

Fibrinogen Milano II: a congenital dysfibrinogenaemia associated with juvenile arterial and venous thrombosis

1 reference

12 December 2020

Formation of a ternary complex between thrombin, fibrin monomer, and heparin influences the action of thrombin on its substrates

1 reference

12 December 2020

Anion-binding exosite of human alpha-thrombin and fibrin(ogen) recognition

1 reference

12 December 2020

Antithrombin I. Inhibition of thrombin generation in plasma by fibrin formation

1 reference

12 December 2020

Three-dimensional modeling of thrombin-fibrinogen interaction

1 reference

12 December 2020

Thrombin, fibrin and platelets: a resonance loop in which von Willebrand factor is a necessary link

1 reference

12 December 2020

Inactivation of thrombin by antithrombin is accompanied by inactivation of regulatory exosite I

1 reference

12 December 2020

Identification of critical residues on thrombin mediating its interaction with fibrin

1 reference

12 December 2020

Binding of fibrin monomer and heparin to thrombin in a ternary complex alters the environment of the thrombin catalytic site, reduces affinity for hirudin, and inhibits cleavage of fibrinogen

1 reference

12 December 2020

The binding of thrombin by fibrin

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0303440101

1 reference

16 August 2017

0 references

1 reference

16 August 2017

1 reference