Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians (Q36807593)

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scientific article published on 9 May 2008

Language	Label	Description	Also known as
English	Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians	scientific article published on 9 May 2008

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scholarly article

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7 January 2020

Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians (English)

1 reference

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7 January 2020

type 2 diabetes

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Ronald Ching Wan Ma

8

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7 January 2020

author name string

Maggie C Y Ng

1

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7 January 2020

Kyong Soo Park

2

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7 January 2020

Bermseok Oh

3

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7 January 2020

Claudia H T Tam

4

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7 January 2020

Young Min Cho

5

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7 January 2020

Hyoung Doo Shin

6

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7 January 2020

Vincent K L Lam

7

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7 January 2020

Wing Yee So

9

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7 January 2020

Yoon Shin Cho

10

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7 January 2020

Hyung-Lae Kim

11

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7 January 2020

Hong Kyu Lee

12

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7 January 2020

Juliana C N Chan

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7 January 2020

Nam H Cho

14

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7 January 2020

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publication date

9 May 2008

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7 January 2020

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7 January 2020

57

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7 January 2020

2226-2233

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7 January 2020

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7 January 2020

Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Genome-wide association studies provide new insights into type 2 diabetes aetiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Genomewide association analysis of coronary artery disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

A common allele on chromosome 9 associated with coronary heart disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

A common variant on chromosome 9p21 affects the risk of myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

A genome-wide association study identifies novel risk loci for type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Mechanisms linking obesity to insulin resistance and type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Epidemic obesity and type 2 diabetes in Asia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Overweight, family history of diabetes and attending schools of lower academic grading are independent predictors for metabolic syndrome in Hong Kong Chinese adolescents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Haploview: analysis and visualization of LD and haplotype maps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

29 September 2017

Variants in the fat mass- and obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

5 September 2018

Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

5 September 2018

Replication and identification of novel variants at TCF7L2 associated with type 2 diabetes in Hong Kong Chinese

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

5 September 2018

Development and validation of stroke risk equation for Hong Kong Chinese patients with type 2 diabetes: the Hong Kong Diabetes Registry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

5 September 2018

Ethnic differences in insulin sensitivity and beta-cell function in premenopausal or early perimenopausal women without diabetes: the Study of Women's Health Across the Nation (SWAN).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

5 September 2018

Familial early-onset type 2 diabetes in Chinese patients: obesity and genetics have more significant roles than autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

5 September 2018

The Pro12 -->Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin secretion in individuals with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

5 September 2018

Abnormal Liver Function Test Predicts Type 2 Diabetes: A community-based prospective study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494677

4 December 2018

Genome-wide Scan for Type 2 Diabetes Loci in Hong Kong Chinese and Confirmation of a Susceptibility Locus on Chromosome 1q21-q25

1 reference

https://pubmed.ncbi.nlm.nih.gov/18469204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association Study of the Genetic Polymorphisms of the Transcription Factor 7-Like 2 (TCF7L2) Gene and Type 2 Diabetes in the Chinese Population

1 reference

https://pubmed.ncbi.nlm.nih.gov/18469204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SNPs in the KCNJ11-ABCC8 gene locus are associated with type 2 diabetes and blood pressure levels in the Japanese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/18469204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/18469204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB07-1583

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18469204%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18469204%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18469204%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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