USE OF FUSED CIRCULATIONS TO INVESTIGATE THE ROLE OF APOLIPOPROTEIN E AS AMYLOID CATALYST AND PERIPHERAL SINK IN ALZHEIMER'S DISEASE. (Q36792697)

16 August 2017

USE OF FUSED CIRCULATIONS TO INVESTIGATE THE ROLE OF APOLIPOPROTEIN E AS AMYLOID CATALYST AND PERIPHERAL SINK IN ALZHEIMER'S DISEASE. (English)

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16 August 2017

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Lars N G Nilsson

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16 August 2017

Sylvia Gografe

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16 August 2017

David A Costa

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16 August 2017

Tiffany Hughes

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16 August 2017

David Dressler

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16 August 2017

Huntington Potter

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16 August 2017

1 February 2012

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Technology and innovation

16 August 2017

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16 August 2017

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16 August 2017

199-208

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1 reference

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1 reference

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1 reference

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Use of in vivo models to study the role of cholesterol in the etiology of Alzheimer's disease.

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The inflammation-induced pathological chaperones ACT and apo-E are necessary catalysts of Alzheimer amyloid formation

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Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

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Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

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Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

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1 reference

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Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro

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Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

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Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

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Apolipoprotein is required for the formation of filamentous amyloid, but not for amorphous Abeta deposition, in an AbetaPP/PS double transgenic mouse model of Alzheimer's disease

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Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

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Isoform-specific effects of apolipoproteins E2, E3, and E4 on cerebral capillary sequestration and blood-brain barrier transport of circulating Alzheimer's amyloid beta.

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Acute phase reactant alpha 1-antichymotrypsin is increased in cerebrospinal fluid and serum of patients with probable Alzheimer disease.

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apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain

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Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation.

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1 reference

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Apolipoprotein E influences amyloid-beta clearance from the murine periphery.

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1 reference

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Novel therapeutic approach for the treatment of Alzheimer's disease by peripheral administration of agents with an affinity to beta-amyloid.

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1 reference

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Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease.

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Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

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1 reference

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Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.

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Alpha-1-antichymotrypsin promotes beta-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease.

5 September 2018

1 reference

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Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.

5 September 2018

1 reference

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Serum alpha 1-antichymotrypsin level as a marker for Alzheimer-type dementia.

5 September 2018

1 reference

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Is Alzheimer's disease an apolipoprotein E amyloidosis?

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1 reference

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Parabiosis in physiological studies

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12 December 2020

Alzheimer A beta neurotoxicity: promotion by antichymotrypsin, ApoE4; inhibition by A beta-related peptides

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12 December 2020

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

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Apolipoprotein E Level in Cerebrospinal Fluid Increases With Aging

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12 December 2020

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

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12 December 2020

Acquired tolerance to homologous transplantation of normal and neoplastic tissues in inbred mice

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12 December 2020

10.3727/194982412X13462021398010

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DOI

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16 August 2017

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16 August 2017

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