Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway (Q36771955)

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scientific article published on 4 December 2015

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English	Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway	scientific article published on 4 December 2015

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scholarly article

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2 March 2020

Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway (English)

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2 March 2020

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reactive oxygen species

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based on heuristic

inferred from title

chronic lymphocytic leukemia

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

Manoj K Kashyap

1

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Johanna Melo-Cardenas

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2 March 2020

author name string

Deepak Kumar

2

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Harrison Jones

3

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Carlos I Amaya-Chanaga

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Michael Y Choi

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Amine Ale-Ali

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2 March 2020

Michelle R Kuhne

8

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Peter Sabbatini

9

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Lewis J Cohen

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2 March 2020

Suresh G Shelat

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2 March 2020

Laura Z Rassenti

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2 March 2020

Thomas J Kipps

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Pina M Cardarelli

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Januario E Castro

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1 January 2016

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2 March 2020

1 reference

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2 March 2020

7

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2 March 2020

3

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2 March 2020

2809-2822

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2 March 2020

Targeting the spliceosome in chronic lymphocytic leukemia with the macrolides FD-895 and pladienolide-B.

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Microenvironment dependency in Chronic Lymphocytic Leukemia: The basis for new targeted therapies

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BMS-936564/MDX-1338: a fully human anti-CXCR4 antibody induces apoptosis in vitro and shows antitumor activity in vivo in hematologic malignancies

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Antibody-induced nonapoptotic cell death in human lymphoma and leukemia cells is mediated through a novel reactive oxygen species-dependent pathway

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AMD3100 disrupts the cross-talk between chronic lymphocytic leukemia cells and a mesenchymal stromal or nurse-like cell-based microenvironment: pre-clinical evidence for its association with chronic lymphocytic leukemia treatments

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N,N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells

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Characterization and application of two novel monoclonal antibodies against human CXCR4: cell proliferation and migration regulation for glioma cell line in vitro by CXCR4/SDF-1alpha signal

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Tiron, a ROS scavenger, protects human lung cancer Calu-6 cells against antimycin A-induced cell death.

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The CXCR4 chemokine receptor in acute and chronic leukaemia: a marrow homing receptor and potential therapeutic target

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Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells.

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Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha

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Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells.

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Bone marrow mesenchymal stromal cells non-selectively protect chronic myeloid leukemia cells from imatinib-induced apoptosis via the CXCR4/CXCL12 axis

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Overexpression of the chemokine receptor CXCR4 in B cell chronic lymphocytic leukemia is associated with increased functional response to stromal cell-derived factor-1 (SDF-1)

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12 December 2020

based on heuristic

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Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/26646452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors that influence short-term homing of human bone marrow-derived mesenchymal stem cells in a xenogeneic animal model

1 reference

https://pubmed.ncbi.nlm.nih.gov/26646452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.6465

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2 March 2020

1 reference

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2 March 2020

1 reference

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2 March 2020

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