CXCR4 and mobilization of hematopoietic precursors. (Q46009370)

18 December 2017

title

CXCR4 and mobilization of hematopoietic precursors. (English)

1 reference

18 December 2017

author name string

Michael P Rettig

1

1 reference

18 December 2017

Pablo Ramirez

2

1 reference

18 December 2017

Bruno Nervi

3

1 reference

18 December 2017

John F DiPersio

4

1 reference

18 December 2017

language of work or name

English

0 references

publication date

1 January 2009

1 reference

18 December 2017

published in

Methods in Enzymology

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18 December 2017

volume

460

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18 December 2017

page(s)

57-90

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18 December 2017

Enhanced unique pattern of hematopoietic cell mobilization induced by the CXCR4 antagonist 4F-benzoyl-TN14003.

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CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers

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7 January 2021

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

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Regulation of CXCR4 signaling

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Sustained proliferation, multi-lineage differentiation and maintenance of primitive human haemopoietic cells in NOD/SCID mice transplanted with human cord blood

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7 January 2021

Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization

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7 January 2021

Identification of hematopoietic stem/progenitor cells: strength and drawbacks of functional assays

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7 January 2021

Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells

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7 January 2021

Efficient mobilization of haematopoietic progenitors after a single injection of pegylated recombinant human granulocyte colony-stimulating factor in mouse strains with distinct marrow-cell pool sizes

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7 January 2021

A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover

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7 January 2021

Rapid mobilization of functional donor hematopoietic cells without G-CSF using AMD3100, an antagonist of the CXCR4/SDF-1 interaction

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7 January 2021

Low CXCR4 membrane expression on CD34(+) cells characterizes cells mobilized to blood

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7 January 2021

Characterization of human hematopoietic cells with short-lived in vivo repopulating activity.

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7 January 2021

Adult mouse hematopoietic stem cells: purification and single-cell assays.

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7 January 2021

The many facets of SDF-1alpha, CXCR4 agonists and antagonists on hematopoietic progenitor cells

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7 January 2021

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

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7 January 2021

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

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7 January 2021

A human CD34(+) subset resides in lymph nodes and differentiates into CD56bright natural killer cells

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7 January 2021

The CXCR4 antagonist AMD3100 releases a subset of G-CSF-primed peripheral blood progenitor cells with specific gene expression characteristics.

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7 January 2021

The chemokine GRObeta mobilizes early hematopoietic stem cells characterized by enhanced homing and engraftment

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7 January 2021

Transmigration of human CD34+ cells

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7 January 2021

The minimum CD34 threshold depends on prior chemotherapy in autologous peripheral blood stem cell recipients

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7 January 2021

Successful PBSC mobilization with high-dose G-CSF for patients failing a first round of mobilization

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7 January 2021

Lineage development of hematopoietic stem and progenitor cells

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7 January 2021

Previously undetected human hematopoietic cell populations with short-term repopulating activity selectively engraft NOD/SCID-beta2 microglobulin-null mice.

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7 January 2021

Small molecules anti-HIV therapeutics targeting CXCR4.

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7 January 2021

Allogeneic peripheral blood stem-cell compared with bone marrow transplantation in the management of hematologic malignancies: an individual patient data meta-analysis of nine randomized trials

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7 January 2021

WHIM syndrome: a genetic disorder of leukocyte trafficking

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7 January 2021

Altered leukocyte response to CXCL12 in patients with warts hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome.

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7 January 2021

Regulation of human chemokine receptors CXCR4. Role of phosphorylation in desensitization and internalization

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7 January 2021

A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells

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7 January 2021

Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells

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7 January 2021

Hematopoietic stem cells

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7 January 2021

The use of experimental murine models to assess novel agents of hematopoietic stem and progenitor cell mobilization.

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7 January 2021

Mobilisation with G-CSF in healthy donors promotes a high but temporal deregulation of genes

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7 January 2021

Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease

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7 January 2021

Human progenitor cells rapidly mobilized by AMD3100 repopulate NOD/SCID mice with increased frequency in comparison to cells from the same donor mobilized by granulocyte colony stimulating factor

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7 January 2021

Allogeneic Stem Cell Transplantation with Peripheral Blood Stem Cells Mobilized by Pegylated G-CSF

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7 January 2021

Leukocytosis and Mobilization of CD34+ Hematopoietic Progenitor Cells by AMD3100, a CXCR4 Antagonist

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7 January 2021

Selective secretion of chemoattractants for haemopoietic progenitor cells by bone marrow endothelial cells: a possible role in homing of haemopoietic progenitor cells to bone marrow

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7 January 2021

NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

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7 January 2021

Rapid and recurrent neutrophil mobilization regulated by T134, a CXCR4 peptide antagonist

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7 January 2021

Differentiation of two types of mobilized peripheral blood stem cells by microRNA and cDNA expression analysis

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing.

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7 January 2021

Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow

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7 January 2021

WHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus-truncated CXCR4

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7 January 2021

Enhanced function with decreased internalization of carboxy-terminus truncated CXCR4 responsible for WHIM syndrome

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7 January 2021

Small molecule CXCR4 chemokine receptor antagonists: developing drug candidates

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7 January 2021

Uncertainty in the niches that maintain haematopoietic stem cells

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7 January 2021

SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

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7 January 2021

Somatic support cells restrict germline stem cell self-renewal and promote differentiation.

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7 January 2021

Factors influencing G-CSF-mediated mobilization of hematopoietic progenitor cells during steady-state hematopoiesis in patients with malignant lymphoma and multiple myeloma

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7 January 2021

The multiple roles of osteoclasts in host defense: bone remodeling and hematopoietic stem cell mobilization

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7 January 2021

Rapid and efficient homing of human CD34(+)CD38(-/low)CXCR4(+) stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2m(null) mice

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7 January 2021

The role of pegfilgrastim in mobilization of hematopoietic stem cells

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7 January 2021

CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion

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7 January 2021

How do stem cells find their way home?

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7 January 2021

Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: implications for gene therapy

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7 January 2021

Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide

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7 January 2021

Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist

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7 January 2021

Purification of hematopoietic stem cells using the side population

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7 January 2021

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

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7 January 2021

The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment

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7 January 2021

G protein-coupled receptor sorting to endosomes and lysosomes

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7 January 2021

Human short-term repopulating stem cells are efficiently detected following intrafemoral transplantation into NOD/SCID recipients depleted of CD122+ cells

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7 January 2021

Characterization of mouse hematopoietic stem and progenitor cells

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

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7 January 2021

Granulocyte colony-stimulating factor generates epigenetic and genetic alterations in lymphocytes of normal volunteer donors of stem cells

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7 January 2021

Cytokines and hematopoietic stem cell mobilization

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7 January 2021

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Kinetics of CXCR-4 and adhesion molecule expression during autologous stem cell mobilisation with G-CSF plus AMD3100 in patients with multiple myeloma

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7 January 2021

Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization

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7 January 2021

Stem-cell ecology and stem cells in motion

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7 January 2021

Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Peripheral blood stem cell mobilization: new regimens, new cells, where do we stand

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

The CXCR4 agonist peptide, CTCE-0021, rapidly mobilizes polymorphonuclear neutrophils and hematopoietic progenitor cells into peripheral blood and synergizes with granulocyte colony-stimulating factor

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7 January 2021

Chemokine-mobilized adult stem cells; defining a better hematopoietic graft

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Limiting factors in murine hematopoietic stem cell assays.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Impact of mobilization and remobilization strategies on achieving sufficient stem cell yields for autologous transplantation.

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7 January 2021

Mobilization of hematopoietic stem and progenitor cells in mice

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7 January 2021

Randomised trial of filgrastim-mobilised peripheral blood progenitor cell transplantation versus autologous bone-marrow transplantation in lymphoma patients

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Duration of sample storage dramatically alters expression of the human immunodeficiency virus coreceptors CXCR4 and CCR5

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Granulocyte colony stimulating factor does not induce long‐term DNA instability in healthy peripheral blood stem cell donors

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Granulocyte-colony stimulating factor administration to healthy individuals and persons with chronic neutropenia or cancer: an overview of safety considerations from the Research on Adverse Drug Events and Reports project.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Plerixafor, a CXCR4 antagonist for the mobilization of hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

In vitro assays for cobblestone area-forming cells, LTC-IC, and CFU-C.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

In vitro migratory capacity of CD34+ cells is related to hematopoietic recovery after autologous stem cell transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Peripheral blood hematopoietic stem cell mobilization and collection efficacy is not an independent prognostic factor for autologous stem cell transplantation

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7 January 2021

The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseases

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Bone-marrow haematopoietic-stem-cell niches

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Mechanisms of hematopoietic stem cell mobilization: when innate immunity assails the cells that make blood and bone

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7 January 2021

A niche maintaining germ line stem cells in the Drosophila ovary

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Genetic regulation of hematopoietic stem cell exhaustion during development and growth

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Pharmacokinetics of pegfilgrastim

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Intracellular localization and constitutive endocytosis of CXCR4 in human CD34+ hematopoietic progenitor cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Small peptide analogs to stromal derived factor-1 enhance chemotactic migration of human and mouse hematopoietic cells

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

Enhanced inhibition of human immunodeficiency virus type 1 by Met-stromal-derived factor 1beta correlates with down-modulation of CXCR4.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2905203-3

7 January 2021

10.1016/S0076-6879(09)05203-3

Identifiers

DOI

1 reference

18 December 2017

PubMed ID

19446720

1 reference

18 December 2017