Cytopenia and autoimmune diseases: a vicious cycle fueled by mTOR dysregulation in hematopoietic stem cells. (Q36756168)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23375848%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Cytopenia and autoimmune diseases: a vicious cycle fueled by mTOR dysregulation in hematopoietic stem cells (English)

1 reference

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23 February 2020

1

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23 February 2020

Xing Chang

series ordinal

2

1 reference

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23 February 2020

Yang Liu

series ordinal

4

1 reference

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23 February 2020

author name string

Qianjin Lu

series ordinal

3

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23 February 2020

publication date

1 February 2013

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23 February 2020

language of work or name

English

0 references

published in

Journal of Autoimmunity

1 reference

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23 February 2020

volume

41

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23 February 2020

page(s)

182-187

1 reference

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publication type of scholarly work

23 February 2020

review article

1 reference

Epigenetics, autoimmunity and hematologic malignancies: A comprehensive review

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TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

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Homeostatic proliferation in the mice with germline FoxP3 mutation and its contribution to fatal autoimmunity

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Use of sirolimus in IPEX and IPEX-like children

29 September 2017

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The TSC1-TSC2 complex is required for proper activation of mTOR complex 2

29 September 2017

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Common variable immune deficiency (CVID) presenting as an autoimmune disease: role of memory B cells

29 September 2017

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IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

29 September 2017

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Expanding mTOR signaling

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FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

29 September 2017

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Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity

29 September 2017

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TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

29 September 2017

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Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus

29 September 2017

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TSC1/TSC2 and Rheb have different effects on TORC1 and TORC2 activity

29 September 2017

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

29 September 2017

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The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis

29 September 2017

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Dysregulation of the TSC-mTOR pathway in human disease

29 September 2017

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The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis

29 September 2017

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29 September 2017

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CD24 expression on T cells is required for optimal T cell proliferation in lymphopenic host

29 September 2017

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Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

29 September 2017

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29 September 2017

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29 September 2017

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TSC2 mediates cellular energy response to control cell growth and survival

29 September 2017

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Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis

29 September 2017

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The tuberous sclerosis complex (TSC) pathway and mechanism of size control

29 September 2017

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Aire regulates negative selection of organ-specific T cells

29 September 2017

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29 September 2017

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Neonates support lymphopenia-induced proliferation.

29 September 2017

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29 September 2017

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29 September 2017

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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12 December 2020

The role of alpha beta+ T cells and homeostatic T cell proliferation in Y-chromosome-associated murine lupus

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12 December 2020

The diabetes-prone BB rat carries a frameshift mutation in Ian4, a positional candidate of Iddm1

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Thymic export function and T cell homeostasis in patients with relapsing remitting multiple sclerosis

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12 December 2020

Thymic function and peripheral T-cell homeostasis in rheumatoid arthritis

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Guillain-Barré syndrome

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Cytotoxic Therapy in Systemic Lupus Erythematosus: Experience from a Single Center

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Neonatal thymectomy results in a repertoire enriched in T cells deleted in adult thymus

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12 December 2020

Safety issues in the management of autoimmune hepatitis

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DiGeorge syndrome with Graves' disease: A case report

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12 December 2020

Ex vivo homeostatic proliferation of CD4+ T cells in rheumatoid arthritis is dysregulated and driven by membrane-anchored TNFalpha

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12 December 2020

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

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12 December 2020

10.1016/J.JAUT.2012.12.011

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23375848%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23375848%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

23375848

1 reference