Valosin-containing Protein (VCP)/p97 Segregase Mediates Proteolytic Processing of Cockayne Syndrome Group B (CSB) in Damaged Chromatin (Q36755008)

16 August 2017

Valosin-containing Protein (VCP)/p97 Segregase Mediates Proteolytic Processing of Cockayne Syndrome Group B (CSB) in Damaged Chromatin (English)

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16 August 2017

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Jinshan He

1

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16 August 2017

Qianzheng Zhu

2

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16 August 2017

Gulzar Wani

3

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16 August 2017

Nidhi Sharma

4

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16 August 2017

Altaf A Wani

5

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16 August 2017

language of work or name

English

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publication date

29 January 2016

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Journal of Biological Chemistry

16 August 2017

13

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inferred from page(s)

published in

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16 August 2017

291

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14

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16 August 2017

7396-7408

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describes a project that uses

16 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4817171/fullTextXML

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cites work

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Dysregulation of gene expression as a cause of Cockayne syndrome neurological disease

29 September 2017

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Ubiquitin-specific protease 7 regulates nucleotide excision repair through deubiquitinating XPC protein and preventing XPC protein from undergoing ultraviolet light-induced and VCP/p97 protein-regulated proteolysis

29 September 2017

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Chromatin retention of DNA damage sensors DDB2 and XPC through loss of p97 segregase causes genotoxicity

29 September 2017

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USP3 counteracts RNF168 via deubiquitinating H2A and γH2AX at lysine 13 and 15.

29 September 2017

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ATP-dependent chromatin remodeling by Cockayne syndrome protein B and NAP1-like histone chaperones is required for efficient transcription-coupled DNA repair

29 September 2017

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p97 complexes as signal integration hubs.

29 September 2017

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NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathway

29 September 2017

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Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair

29 September 2017

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UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair

29 September 2017

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Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

29 September 2017

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The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

29 September 2017

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The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks.

29 September 2017

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BRCA1 contributes to transcription-coupled repair of DNA damage through polyubiquitination and degradation of Cockayne syndrome B protein

29 September 2017

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Cdc48: a power machine in protein degradation

29 September 2017

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XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase.

29 September 2017

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Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

29 September 2017

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Cdc48/p97 mediates UV-dependent turnover of RNA Pol II.

29 September 2017

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UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover

29 September 2017

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Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated disease

29 September 2017

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Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1

29 September 2017

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Activation of RNA polymerase I transcription by cockayne syndrome group B protein and histone methyltransferase G9a

29 September 2017

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Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo

29 September 2017

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Cockayne syndrome group B protein (CSB) plays a general role in chromatin maintenance and remodeling

29 September 2017

1 reference

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CSA-dependent degradation of CSB by the ubiquitin-proteasome pathway establishes a link between complementation factors of the Cockayne syndrome

29 September 2017

1 reference

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Diverse functions with a common regulator: ubiquitin takes command of an AAA ATPase

29 September 2017

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Cullin 4A-mediated proteolysis of DDB2 protein at DNA damage sites regulates in vivo lesion recognition by XPC.

29 September 2017

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Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome

29 September 2017

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DNA repair factor XPC is modified by SUMO-1 and ubiquitin following UV irradiation

29 September 2017

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DNA damage stabilizes interaction of CSB with the transcription elongation machinery

29 September 2017

1 reference

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Tumour suppression: disruption of HAUSP gene stabilizes p53

29 September 2017

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In vivo recruitment of XPC to UV-induced cyclobutane pyrimidine dimers by the DDB2 gene product

29 September 2017

1 reference

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The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817171

Rescue of arrested RNA polymerase II complexes

29 September 2017

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Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates

29 September 2017

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Mechanisms of transcription-coupled DNA repair

29 September 2017

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Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.

29 September 2017

1 reference

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The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817171

HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins

29 September 2017

1 reference

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Sequential assembly of the nucleotide excision repair factors in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817171

ATP-dependent chromatin remodeling by the Cockayne syndrome B DNA repair-transcription-coupling factor.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817171

Molecular mechanism of nucleotide excision repair.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817171

Biochemical and biological characterization of wild-type and ATPase-deficient Cockayne syndrome B repair protein.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817171

Cockayne syndrome group B protein enhances elongation by RNA polymerase II

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817171

The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817171

UV-induced ubiquitination of RNA polymerase II: a novel modification deficient in Cockayne syndrome cells

29 September 2017

1 reference

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Role of DNA excision repair gene defects in the etiology of cancer.

29 September 2017

1 reference

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KIAA1530 protein is recruited by Cockayne syndrome complementation group protein A (CSA) to participate in transcription-coupled repair (TCR).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817171

Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin

28 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M115.705350

21 January 2018

Identifiers

DOI

10.1074/JBC.M115.705350

1 reference

16 August 2017

1 reference

16 August 2017

1 reference