Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs (Q36734694)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18480256%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs (English)

1 reference

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7 January 2020

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10

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7 January 2020

James Shorter

19

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7 January 2020

16

Stephen L Buchwald

1 reference

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7 January 2020

18

Susan Lindquist

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7 January 2020

author name string

Huan Wang

1

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7 January 2020

Martin L Duennwald

2

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7 January 2020

Blake E Roberts

3

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7 January 2020

Leslie M Rozeboom

4

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7 January 2020

Yingxin L Zhang

5

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7 January 2020

Andrew D Steele

6

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7 January 2020

Rajaraman Krishnan

7

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7 January 2020

Linhui Julie Su

8

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7 January 2020

Drees Griffin

9

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7 January 2020

Edward J Hennessy

11

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7 January 2020

Peter Weigele

12

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7 January 2020

Barbara J Blanchard

13

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7 January 2020

Jonathan King

14

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7 January 2020

Ashok A Deniz

15

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7 January 2020

Vernon M Ingram

17

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7 January 2020

language of work or name

English

0 references

publication date

14 May 2008

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

7 January 2020

published in

1 reference

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7 January 2020

volume

105

1 reference

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7 January 2020

issue

20

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7 January 2020

page(s)

7159-7164

1 reference

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Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications

7 January 2020

cites work

1 reference

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Atomic structures of amyloid cross-beta spines reveal varied steric zippers

30 September 2017

1 reference

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A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures.

30 September 2017

1 reference

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Structural models of amyloid-like fibrils

30 September 2017

1 reference

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Small molecule inhibitors of alpha-synuclein filament assembly

30 September 2017

1 reference

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Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism

30 September 2017

1 reference

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3D structure of Alzheimer's amyloid-beta(1-42) fibrils

30 September 2017

1 reference

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Structural insights into a yeast prion illuminate nucleation and strain diversity

30 September 2017

1 reference

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Prions as adaptive conduits of memory and inheritance

30 September 2017

1 reference

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Molecular basis for amyloid fibril formation and stability

30 September 2017

1 reference

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Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule

30 September 2017

1 reference

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438221

A specific mechanism of nonspecific inhibition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438221

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438221

Prevention of transthyretin amyloid disease by changing protein misfolding energetics.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438221

Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438221

Changes in the middle region of Sup35 profoundly alter the nature of epigenetic inheritance for the yeast prion [PSI+]

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438221

Nucleated conformational conversion and the replication of conformational information by a prion determinant

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438221

Self-seeded fibers formed by Sup35, the protein determinant of [PSI+], a heritable prion-like factor of S. cerevisiae.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438221

Point substitution in the central hydrophobic cluster of a human beta-amyloid congener disrupts peptide folding and abolishes plaque competence

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438221

Support for the prion hypothesis for inheritance of a phenotypic trait in yeast

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438221

Alternative assembly pathways of the amyloidogenic yeast prion determinant Sup35-NM

30 September 2017

1 reference

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Prion recognition elements govern nucleation, strain specificity and species barriers

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438221

Destruction or potentiation of different prions catalyzed by similar Hsp104 remodeling activities

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438221

Dianilinophthalimides: potent and selective, ATP-competitive inhibitors of the EGF-receptor protein tyrosine kinase

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438221

Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease beta A4 peptides

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438221

Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models

28 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0801934105

Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0801934105

Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0801934105

The role of conformational flexibility in prion propagation and maintenance for Sup35p

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18480256

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0801934105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18480256%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18480256%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference