Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule (Q24563817)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15388848%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

title

Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule (English)

1 reference

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2 January 2020

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4

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2 January 2020

author name string

Barbara J Blanchard

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15388848%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Albert Chen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15388848%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Leslie M Rozeboom

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15388848%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Peter Weigele

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15388848%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Vernon M Ingram

6

1 reference

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2 January 2020

language of work or name

English

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publication date

23 September 2004

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15388848%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

2 January 2020

number of pages

7

1 reference

based on heuristic

inferred from page(s)

published in

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2 January 2020

volume

101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15388848%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

page(s)

14326-14332

1 reference

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2 January 2020

issue

40

1 reference

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Elimination of Amyloid beta Neurotoxicity

2 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

24 March 2017

1 reference

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Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

Morphology of the seven T-bacteriophages

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

Eliminating membrane depolarization caused by the Alzheimer peptide Abeta(1-42, aggr.).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

Mechanism of membrane depolarization caused by the Alzheimer Abeta1-42 peptide

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

Mechanism and prevention of neurotoxicity caused by beta-amyloid peptides: relation to Alzheimer's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

[(Alkylamino)methyl]acrylophenones: potent and selective inhibitors of the epidermal growth factor receptor protein tyrosine kinase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

Selective phosphorylation of adult tau isoforms in mature hippocampal neurons exposed to fibrillar A beta.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=521943

An improved method of preparing the amyloid beta-protein for fibrillogenesis and neurotoxicity experiments.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0405941101

Assembly of A beta amyloid protofibrils: an in vitro model for a possible early event in Alzheimer's disease.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0405941101

Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15388848

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0405941101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15388848%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

0 references

1 reference

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2 January 2020

1 reference