Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB. (Q36709792)

15 August 2017

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB. (English)

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Maria Antonietta De Matteis

15 August 2017

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17

Maria Antonietta De Matteis

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Rossella Venditti

Rossella Venditti

6

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Wuyang Wang

Wuyang Wang

12

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Qiong Gao

Qiong Gao

13

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Diego De Stefani

Diego De Stefani

5

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Diego Luis Medina

Diego L Medina

1

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Carmine Settembre

Carmine Settembre

11

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Andrea Ballabio

Andrea Ballabio

18

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Andrea Armani

Andrea Armani

4

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author name string

Simone Di Paola

2

1 reference

15 August 2017

Ivana Peluso

3

1 reference

15 August 2017

Sandro Montefusco

7

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15 August 2017

Anna Scotto-Rosato

8

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15 August 2017

Carolina Prezioso

9

1 reference

15 August 2017

Alison Forrester

10

1 reference

15 August 2017

Haoxing Xu

14

1 reference

15 August 2017

Marco Sandri

15

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15 August 2017

Rosario Rizzuto

16

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15 August 2017

1 March 2015

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15 August 2017

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15 August 2017

17

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15 August 2017

288-299

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15 August 2017

3

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describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4801004/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ncb3114

0 references

cites work

MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activity

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A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis

30 September 2017

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Signals from the lysosome: a control centre for cellular clearance and energy metabolism

30 September 2017

1 reference

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TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

30 September 2017

1 reference

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A RANKL-PKCβ-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts

30 September 2017

1 reference

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RRAG GTPases link nutrient availability to gene expression, autophagy and lysosomal biogenesis

30 September 2017

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Bidirectional Ca²⁺ signaling occurs between the endoplasmic reticulum and acidic organelles

30 September 2017

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The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis

30 September 2017

1 reference

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MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.

30 September 2017

1 reference

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A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

30 September 2017

1 reference

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Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

30 September 2017

1 reference

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Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics

30 September 2017

1 reference

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Cardiomyocyte calcineurin signaling in subcellular domains: from the sarcolemma to the nucleus and beyond

30 September 2017

1 reference

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mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

30 September 2017

1 reference

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Physical exercise stimulates autophagy in normal skeletal muscles but is detrimental for collagen VI-deficient muscles

30 September 2017

1 reference

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Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease

30 September 2017

1 reference

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Transcriptional activation of lysosomal exocytosis promotes cellular clearance

30 September 2017

1 reference

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Transcriptional gene network inference from a massive dataset elucidates transcriptome organization and gene function.

30 September 2017

1 reference

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TFEB links autophagy to lysosomal biogenesis

30 September 2017

1 reference

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UniProt Knowledgebase: a hub of integrated protein data

30 September 2017

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The proteome of lysosomes

30 September 2017

1 reference

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PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome

30 September 2017

1 reference

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Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Mammalian autophagy: core molecular machinery and signaling regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

The delivery of endocytosed cargo to lysosomes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Regulation mechanisms and signaling pathways of autophagy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

A gene network regulating lysosomal biogenesis and function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

NAADP mobilizes calcium from acidic organelles through two-pore channels

30 September 2017

1 reference

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AmiGO: online access to ontology and annotation data

30 September 2017

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McKusick's Online Mendelian Inheritance in Man (OMIM)

30 September 2017

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ARAP1 regulates EGF receptor trafficking and signalling.

30 September 2017

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Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

30 September 2017

1 reference

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FoxO3 controls autophagy in skeletal muscle in vivo

30 September 2017

1 reference

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Lysosomes: fusion and function

30 September 2017

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30 September 2017

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Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2.

30 September 2017

1 reference

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Direct observation of individual endogenous protein complexes in situ by proximity ligation

30 September 2017

1 reference

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Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Microdomains of intracellular Ca2+: molecular determinants and functional consequences.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

30 September 2017

The lysosome turns fifty

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

NFAT proteins: key regulators of T-cell development and function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

A PtdIns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Identification and characterization of a novel nuclear factor of activated T-cells-1 isoform expressed in mouse brain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Ca2+-dependent transcriptional repression and derepression: DREAM, a direct effector

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Calcineurin: form and function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Cloning of the gene encoding a novel integral membrane protein, mucolipidin-and identification of the two major founder mutations causing mucolipidosis type IV

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Cain, a novel physiologic protein inhibitor of calcineurin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Transcription factors of the NFAT family: regulation and function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Calcineurin: a calcium- and calmodulin-binding protein of the nervous system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

The return of the nucleus: transcriptional and epigenetic control of autophagy.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Higher activation of autophagy in skeletal muscle of mice during endurance exercise in the fasted state

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Identification of the gene causing mucolipidosis type IV.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4801004

Discovery of a Ca2+- and calmodulin-dependent protein phosphatase: probable identity with calcineurin (CaM-BP80)

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25720963

12 December 2020

inferred from PubMed ID database lookup

Mitochondrial fusion directs cardiomyocyte differentiation via calcineurin and Notch signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25720963

12 December 2020

inferred from PubMed ID database lookup

The use of aequorin and its variants for Ca2+ measurements

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25720963

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCB3114

1 reference

15 August 2017

1 reference

15 August 2017

1 reference