Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases (Q36675286)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

0 references

0 references

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Amber N McElroy

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Colby Starker

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Daniel F Voytas

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

16

Manfred Schmidt

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

15

Christof von Kalle

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

22

Bruce R Blazar

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

18

Keli L Hippen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

author name string

Mark J Osborn

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Beau R Webber

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Friederike Knipping

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Cara-lin Lonetree

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Nicole Tennis

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Anthony P DeFeo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Catherine Lee

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Sarah Merkel

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Troy C Lund

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Karen S Kelly-Spratt

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Michael C Jensen

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Richard Gabriel

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Jeffrey S Miller

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Andrew M Scharenberg

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

publication date

27 October 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

number of pages

12

1 reference

based on heuristic

inferred from page(s)

published in

Molecular Therapy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

page(s)

570-581

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

Molecular and cellular insights into T cell exhaustion

28 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Multiplex Genome-Edited T-cell Manufacturing Platform for "Off-the-Shelf" Adoptive T-cell Immunotherapies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Quantifying on- and off-target genome editing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Chimeric antigen receptor T cells for sustained remissions in leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

DNA targeting specificity of RNA-guided Cas9 nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

TALEN-based gene correction for epidermolysis bullosa.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

RNA-programmed genome editing in human cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

RNA-guided human genome engineering via Cas9

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Multiplex genome engineering using CRISPR/Cas systems

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Common fragile sites: genomic hotspots of DNA damage and carcinogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Efficient TALEN-mediated gene knockout in livestock

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Coupling endonucleases with DNA end-processing enzymes to drive gene disruption

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Bioinformatic clonality analysis of next-generation sequencing-derived viral vector integration sites

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

An unbiased genome-wide analysis of zinc-finger nuclease specificity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Homing endonucleases: from microbial genetic invaders to reagents for targeted DNA modification

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

A rapid and general assay for monitoring endogenous gene modification

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Sleeping beauty transposition from nonintegrating lentivirus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

The 3' untranslated region of the human interferon-beta mRNA has an inhibitory effect on translation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

TALEN-mediated editing of endogenous T-cell receptors facilitates efficient reprogramming of T lymphocytes by lentiviral gene transfer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Transient cold shock enhances zinc-finger nuclease-mediated gene disruption.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786913

Zinc fingers hit off target

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26502778

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MT.2015.197

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26502778%20AND%20SRC:MED&resulttype=core&format=json