The dark side of the NGF family: neurotrophins in neoplasias (Q36654494)

15 August 2017

1 reference

title

The dark side of the NGF family: neurotrophins in neoplasias (English)

1 reference

15 August 2017

Alex Krüttgen

1

1 reference

PubMed ID

17107600

15 August 2017

Imke Schneider

series ordinal

2

1 reference

PubMed ID

17107600

15 August 2017

Joachim Weis

series ordinal

3

1 reference

15 August 2017

1 October 2006

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15 August 2017

1 reference

15 August 2017

16

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15 August 2017

4

1 reference

15 August 2017

304-310

1 reference

A BDNF autocrine loop in adult sensory neurons prevents cell death.

15 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Nerve growth factor and its low-affinity receptor promote Schwann cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Defective downregulation of receptor tyrosine kinases in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Signal transduction gRABs attention

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Gene transfer and molecular cloning of the human NGF receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Human trk oncogenes activated by point mutation, in-frame deletion, and duplication of the tyrosine kinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Molecular characterization of neurotrophin expression and the corresponding tropomyosin receptor kinases (trks) in epithelial and stromal cells of the human prostate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Nerve growth factor overexpression and autocrine loop in breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Nerve growth factor receptors and signaling in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Apoptosis, neuronal maturation, and neurotrophin expression within medulloblastoma nodules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Neurotrophin effects on neuroblastoma cells: correlation with trk and p75NTR expression and influence of Trk receptor bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Low-affinity nerve growth factor receptor (p75) in dermatofibrosarcoma protuberans and other nonneural tumors: a study of 1,150 tumors and fetal and adult normal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

The p75 neurotrophin receptor: multiple interactors and numerous functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Retrograde neurotrophin signaling: Trk-ing along the axon

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Novel class of pain drugs based on antagonism of NGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Long-distance retrograde neurotrophic signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Neurotrophins: roles in neuronal development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Abundant but inactive-state gp140proto-trk is expressed in neuroblastomas of patients with good prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

A comparison of the cytoplasmic domains of the Fas receptor and the p75 neurotrophin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

TrkA induces apoptosis of neuroblastoma cells and does so via a p53-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Purification and amino terminal sequencing of human melanoma nerve growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Nerve growth factor (NGF) induces neuronal differentiation in neuroblastoma cells transfected with the NGF receptor cDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Roles of trk family neurotrophin receptors in medullary thyroid carcinoma development and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Epidermal growth factor, neurotrophins and the metastatic cascade in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

BDNF is expressed in skeletal muscle satellite cells and inhibits myogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Expression and function of TRK-B and BDNF in human neuroblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Neurotrophin effects on eosinophils in allergic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Nerve growth factor stimulates MMP-2 expression and activity and increases invasion by human pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Nerve growth factor induces growth and differentiation of human B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

TrkB receptors are required for follicular growth and oocyte survival in the mammalian ovary

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Specific neuronal expression of human NGF receptors in the basal forebrain and cerebellum of transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

A pro-apoptotic fragment of the p75 neurotrophin receptor is expressed in p75NTRExonIV null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

A neurotrophin axis in myeloma: TrkB and BDNF promote tumor-cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Prediction of central nervous system embryonal tumour outcome based on gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Gene transfer and molecular cloning of the rat nerve growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Pathology and molecular genetics of astrocytic gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Neurotrophins and neurotrophin receptors in human lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Neurotrophin signaling through the p75 neurotrophin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Autocrine expression of neurotrophins and their receptors in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Neurotrophin-induced melanoma cell migration is mediated through the actin-bundling protein fascin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Early days of the nerve growth factor proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Mitogenesis in glioblastoma multiforme cell lines: a role for NGF and its TrkA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Functions of the neurotrophins during nervous system development: what the knockouts are teaching us.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Signal transduction and endocytosis: close encounters of many kinds

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Signal transduction pathways through TRK-A and TRK-B receptors in human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

TrkA alternative splicing: a regulated tumor-promoting switch in human neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Neurotrophins regulate sequential changes in neurotrophin receptor expression by sympathetic neuroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Expression of the neurotrophin receptors Trk A and Trk B in adult human astrocytoma and glioblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Coronary vessel development requires activation of the TrkB neurotrophin receptor by the Wilms' tumor transcription factor Wt1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Correlation of overexpression of the low-affinity p75 neurotrophin receptor with augmented invasion and heparanase production in human malignant melanoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Trk A, B, and C are commonly expressed in human astrocytes and astrocytic gliomas but not by human oligodendrocytes and oligodendroglioma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Selective small molecule peptidomimetic ligands of TrkC and TrkA receptors afford discrete or complete neurotrophic activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

Functions and mechanisms of retrograde neurotrophin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2006.00037.X

10.1111/J.1750-3639.2006.00037.X

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

17107600