Mice with hepatocyte-specific FXR deficiency are resistant to spontaneous but susceptible to cholic acid-induced hepatocarcinogenesis. (Q36638394)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26744468%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Mice with hepatocyte-specific FXR deficiency are resistant to spontaneous but susceptible to cholic acid-induced hepatocarcinogenesis (English)

1 reference

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4 March 2020

1

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4 March 2020

author name string

Yan Zhu

2

1 reference

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4 March 2020

Guodong Li

3

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4 March 2020

Jessica A Williams

4

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4 March 2020

Kyle Buckley

5

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4 March 2020

Ossama Tawfik

6

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4 March 2020

James P Luyendyk

7

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4 March 2020

Grace L Guo

8

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4 March 2020

language of work or name

1 reference

7 January 2016

1 reference

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American Journal of Physiology - Gastrointestinal and Liver Physiology

4 March 2020

published in

1 reference

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4 March 2020

volume

310

1 reference

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4 March 2020

issue

5

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4 March 2020

page(s)

G295-302

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Dysregulation of bile acid homeostasis in parenteral nutrition mouse model

4 March 2020

cites work

1 reference

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Mechanisms of STAT3 activation in the liver of FXR knockout mice

30 September 2017

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Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity.

30 September 2017

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Small heterodimer partner overexpression partially protects against liver tumor development in farnesoid X receptor knockout mice.

30 September 2017

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Bile Acid Receptors and Liver Cancer

30 September 2017

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Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist

30 September 2017

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Cross-regulation of protein stability by p53 and nuclear receptor SHP.

30 September 2017

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Loss of FXR protects against diet-induced obesity and accelerates liver carcinogenesis in ob/ob mice

30 September 2017

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Increased activation of the Wnt/β-catenin pathway in spontaneous hepatocellular carcinoma observed in farnesoid X receptor knockout mice

30 September 2017

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NF-κB and STAT3 - key players in liver inflammation and cancer

30 September 2017

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Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice

30 September 2017

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A pathway involving farnesoid X receptor and small heterodimer partner positively regulates hepatic sirtuin 1 levels via microRNA-34a inhibition

30 September 2017

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Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine.

30 September 2017

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STATs in cancer inflammation and immunity: a leading role for STAT3

30 September 2017

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Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development

30 September 2017

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Farnesoid X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response

30 September 2017

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Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice

30 September 2017

1 reference

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Bile acid transport in sister of P-glycoprotein (ABCB11) knockout mice

30 September 2017

1 reference

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Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis

30 September 2017

1 reference

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Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

30 September 2017

1 reference

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Bile acids: natural ligands for an orphan nuclear receptor

30 September 2017

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Identification of a nuclear receptor for bile acids

30 September 2017

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Hepatocyte-specific deletion of farnesoid X receptor delays but does not inhibit liver regeneration after partial hepatectomy in mice

30 September 2017

1 reference

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Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice

28 June 2018

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Nuclear bile acid receptor FXR protects against intestinal tumorigenesis

28 June 2018

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Promotive effect of primary and secondary bile acids on the induction of gamma-glutamyl transpeptidase-positive liver cell foci as a possible endogenous factor for hepatocarcinogenesis in rats

28 June 2018

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Liver Carcinogenesis by Diethylnitrosamine in the Rat

28 June 2018

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Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor

28 June 2018

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Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes

20 September 2018

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Studies on initiating activity of secondary bile acids for rat hepatocarcinogenesis

20 September 2018

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Prevention of spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice by intestinal-specific farnesoid X receptor reactivation

20 September 2018

1 reference

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Validating Stat3 in cancer therapy

21 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26744468

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Promotive effects of steroids and bile acids on hepatocarcinogenesis initiated by diethylnitrosamine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26744468

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/AJPGI.00134.2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26744468%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26744468%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference