Farnesoid X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response (Q28586517)

GOA release 2020-03-11

author name string

Yan-Dong Wang

1

1 reference

31 January 2017

Wei-Dong Chen

2

1 reference

31 January 2017

Meihua Wang

3

1 reference

31 January 2017

Donna Yu

4

1 reference

31 January 2017

Barry M. Forman

5

1 reference

31 January 2017

Wendong Huang

Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine

6

1 reference

31 January 2017

language of work or name

English

0 references

publication date

1 November 2008

1 reference

31 January 2017

1 reference

31 January 2017

48

1 reference

31 January 2017

1632–1643

1 reference

31 January 2017

5

1 reference

31 January 2017

1 reference

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Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma

17 March 2017

1 reference

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A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma

17 March 2017

1 reference

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To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis

17 March 2017

1 reference

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17 March 2017

1 reference

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Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

17 March 2017

1 reference

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The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056574

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

17 March 2017

1 reference

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17 March 2017

1 reference

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1 reference

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17 March 2017

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NF-kappaB: linking inflammation and immunity to cancer development and progression

7 April 2017

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NF-kappaB functions as a tumour promoter in inflammation-associated cancer

7 April 2017

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IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

7 April 2017

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

7 April 2017

1 reference

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Farnesoid X receptor protects liver cells from apoptosis induced by serum deprivation in vitro and fasting in vivo

7 April 2017

1 reference

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FXR, a target for different diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056574

Farnesoid x receptor ligands inhibit vascular smooth muscle cell inflammation and migration

29 September 2017

1 reference

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Nuclear factor-kappaB and the hepatic inflammation-fibrosis-cancer axis

29 September 2017

1 reference

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Liver X receptor-alpha gene expression is positively regulated by thyroid hormone

29 September 2017

1 reference

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Liver receptor homolog 1 is a negative regulator of the hepatic acute-phase response

29 September 2017

1 reference

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Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation

29 September 2017

1 reference

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Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

29 September 2017

1 reference

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Transcriptional crosstalk between nuclear receptors and cytokine signal transduction pathways in immunity

29 September 2017

1 reference

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High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding

29 September 2017

1 reference

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Prevention of cholesterol gallstone disease by FXR agonists in a mouse model.

29 September 2017

1 reference

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Nuclear factor-kappaB: the enemy within

29 September 2017

1 reference

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Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR.

29 September 2017

1 reference

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The pathology of cholestasis

29 September 2017

1 reference

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Inflammation and Cancer. I. Rodent models of infectious gastrointestinal and liver cancer

29 September 2017

1 reference

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A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056574

Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056574

Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056574

Cross-talk between glucocorticoid receptor and AP-1.

29 September 2017

1 reference

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AP-1--glucocorticoid receptor crosstalk taken to a higher level

29 September 2017

1 reference

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The peroxisome proliferator-activated receptor(PPARgamma) as a regulator of monocyte/macrophage function.

29 September 2017

1 reference

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Molecular determinants of crosstalk between nuclear receptors and toll-like receptors.

29 September 2017

1 reference

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Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice

3 June 2018

1 reference

Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents.

21 January 2018

1 reference

Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor.

21 January 2018

1 reference

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

Repression of farnesoid X receptor during the acute phase response

21 January 2018

1 reference

Ursodeoxycholic acid inhibits interleukin 1 beta [corrected] and deoxycholic acid-induced activation of NF-kappaB and AP-1 in human colon cancer cells

21 January 2018

1 reference

The bile acid deoxycholic acid (DCA) at neutral pH activates NF-kappaB and induces IL-8 expression in oesophageal cells in vitro

21 January 2018

1 reference

Mechanism of suppression of cytochrome P-450 1A1 expression by tumor necrosis factor-alpha and lipopolysaccharide

21 January 2018

1 reference

Hypoxia-induced VEGF enhances tumor survivability via suppression of serum deprivation-induced apoptosis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18972444

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The farnesoid X-activated receptor mediates bile acid activation of phospholipid transfer protein gene expression

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18972444

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18972444

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/HEP.22519

1 reference

2219993

2219993

1 reference

1 reference

1 reference