Induction of apoptosis in myeloid leukaemic cells by ribozymes targeted against AML1/MTG8 (Q36619128)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10188872%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

title

Induction of apoptosis in myeloid leukaemic cells by ribozymes targeted against AML1/MTG8 (English)

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3 December 2019

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1

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3 December 2019

author name string

Kizaki M

2

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3 December 2019

Kobayashi H

3

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3 December 2019

Muto A

4

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3 December 2019

Ikeda Y

5

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3 December 2019

language of work or name

English

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publication date

1 March 1999

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British Journal of Cancer

3 December 2019

published in

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3 December 2019

volume

79

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3 December 2019

issue

9-10

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3 December 2019

page(s)

1325-1331

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https://scigraph.springernature.com/pub.10.1038/sj.bjc.6690214

3 December 2019

exact match

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cites work

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30 September 2017

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CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter

30 September 2017

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Designing of chimeric DNA/RNA hammerhead ribozymes to be targeted against AML1/MTG8 mRNA.

30 September 2017

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Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

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The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript

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Incorporation of the catalytic domain of a hammerhead ribozyme into antisense RNA enhances its inhibitory effect on the replication of human immunodeficiency virus type 1.

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Selective cleavage of bcr-abl chimeric RNAs by a ribozyme targeted to non-contiguous sequences

30 September 2017

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PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells

30 September 2017

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Growth inhibition and induction of differentiation of t(8;21) acute myeloid leukemia cells by the DNA-binding domain of PEBP2 and the AML1/MTG8(ETO)-specific antisense oligonucleotide

30 September 2017

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Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1)

30 September 2017

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The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation

30 September 2017

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Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia

30 September 2017

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An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt

30 September 2017

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The AML1/ETO fusion protein blocks transactivation of the GM-CSF promoter by AML1B.

30 September 2017

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Multi-unit ribozyme-mediated cleavage of bcr-abl mRNA in myeloid leukemias.

30 September 2017

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Ribozymes cleave the AML1/MTG8 fusion transcript and inhibit proliferation of leukemic cells with t(8;21).

30 September 2017

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30 September 2017

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30 September 2017

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28 June 2018

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28 June 2018

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28 June 2018

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Positive and negative regulation of granulocyte-macrophage colony-stimulating factor promoter activity by AML1-related transcription factor, PEBP2.

28 June 2018

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28 June 2018

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28 June 2018

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The prognostic value of cytogenetic analyses in patients with acute nonlymphocytic leukemia treated with the same intensive chemotherapy

28 June 2018

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Expression of a knocked-in AML1-ETO leukemia gene inhibits the establishment of normal definitive hematopoiesis and directly generates dysplastic hematopoietic progenitors.

28 June 2018

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Simple RNA enzymes with new and highly specific endoribonuclease activities

20 September 2018

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In vitro and in vivo effects of synthetic ribozymes targeted against BCR/ABL mRNA

20 September 2018

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12 December 2020

A ribozyme which discriminates in vitro between PML/RAR alpha, the t(15;17)-associated fusion RNA of acute promyelocytic leukemia, and PML and RAR alpha, the transcripts from the nonrearranged alleles

1 reference

12 December 2020

Serial quantification of minimal residual disease of t(8;21) acute myelogenous leukaemia with RT-competitive PCR assay

1 reference

12 December 2020

Construction of a series of several self-cleaving RNA duplexes using synthetic 21-mers

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJC.6690214

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10188872%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10188872%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

1 reference