Monocytes and neutrophils as 'bad guys' for the outcome of interleukin-2 with and without histamine in metastatic renal cell carcinoma--results from a randomised phase II trial (Q36613642)

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scientific article published on January 2006

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English	Monocytes and neutrophils as 'bad guys' for the outcome of interleukin-2 with and without histamine in metastatic renal cell carcinoma--results from a randomised phase II trial	scientific article published on January 2006

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scholarly article

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16 January 2020

Monocytes and neutrophils as 'bad guys' for the outcome of interleukin-2 with and without histamine in metastatic renal cell carcinoma--results from a randomised phase II trial (English)

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16 January 2020

phase II clinical trial

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1

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16 January 2020

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M Hokland

2

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16 January 2020

N Marcussen

3

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16 January 2020

H H Torp Madsen

4

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16 January 2020

H von der Maase

5

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16 January 2020

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1 January 2006

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16 January 2020

British Journal of Cancer

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16 January 2020

94

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16 January 2020

2

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16 January 2020

218-226

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16 January 2020

https://scigraph.springernature.com/pub.10.1038/sj.bjc.6602937

0 references

Two randomised phase II trials of subcutaneous interleukin-2 and histamine dihydrochloride in patients with metastatic renal cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Tumor-associated macrophages: the double-edged sword in cancer progression.

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30 September 2017

Effective immunotherapy against cancer: a question of overcoming immune suppression and immune escape?

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30 September 2017

Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues.

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30 September 2017

Role of infiltrated leucocytes in tumour growth and spread

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30 September 2017

Tumour-educated macrophages promote tumour progression and metastasis

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30 September 2017

Metastatic renal carcinoma comprehensive prognostic system

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Inflammation and cancer

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30 September 2017

Intratumoural and peripheral blood lymphocyte subsets in patients with metastatic renal cell carcinoma undergoing interleukin-2 based immunotherapy: association to objective response and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Histamine in cancer immunotherapy: a preclinical background.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Cancer immunotherapy with natural killer cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Outpatient treatment with subcutaneous histamine dihydrochloride in combination with interleukin-2 and interferon-alpha in patients with metastatic renal cell carcinoma: results of an open single-armed multicentre phase II study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Chronic immune activation and inflammation as the cause of malignancy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Progress in human tumour immunology and immunotherapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Inflammation and cancer: back to Virchow?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

The Hallmarks of Cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Histaminergic regulation of NK cells. Role of monocyte-derived reactive oxygen metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Interleukin-2 based home therapy of metastatic renal cell carcinoma: risks and benefits in 215 consecutive single institution patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Reporting results of cancer treatment

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30 September 2017

Suppression of natural killing in vitro by monocytes and polymorphonuclear leukocytes: requirement for reactive metabolites of oxygen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

30 September 2017

Some new, simple and efficient stereological methods and their use in pathological research and diagnosis.

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30 September 2017

Role of histamine in natural killer cell-mediated resistance against tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

28 June 2018

Immunotherapy with histamine and interleukin 2 in malignant melanoma with liver metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

20 September 2018

Leukocyte orchestration in blood and tumour tissue following interleukin-2 based immunotherapy in metastatic renal cell carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

20 September 2018

Histamine inhibits neutrophil NADPH oxidase activity triggered by the lipoxin A4 receptor-specific peptide agonist Trp-Lys-Tyr-Met-Val-Met.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

20 September 2018

A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

20 September 2018

A phase II study of outpatient subcutaneous histamine dihydrochloride, interleukin-2 and interferon-alpha in patients with metastatic melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

20 September 2018

A multicentre, randomized study to evaluate the safety and efficacy of histamine dihydrochloride and interferon-alpha-2b for the treatment of chronic hepatitis C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

20 September 2018

Results from a randomized phase III study comparing combined treatment with histamine dihydrochloride plus interleukin-2 versus interleukin-2 alone in patients with metastatic melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

20 September 2018

Inflammatory cells and cancer: think different!

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

20 September 2018

Histamine H2-receptor-mediated regulation of human natural killer cell activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361121

20 September 2018

Variable expression of CD3-ζ chain in tumor-infiltrating lymphocytes (TIL) derived from renal-cell carcinoma: Relationship with til phenotype and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6602937

21 January 2018

A Paracrine Loop between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6602937

21 January 2018

Prognostic factors of survival and rapid progression in 782 patients with metastatic renal carcinomas treated by cytokines: a report from the Groupe Français d'Immunothérapie

1 reference

https://pubmed.ncbi.nlm.nih.gov/16434984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and necrosis promote tumour growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/16434984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic activation of human natural killer cell cytotoxicity by histamine and interleukin-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/16434984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-2 dose, blood monocyte and CD25+ lymphocyte counts as predictors of clinical response to interleukin-2 therapy in patients with renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16434984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of T-cell receptor zeta chain and p56lck in T-cells infiltrating human renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16434984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis in NK cells by monocyte-derived reactive oxygen metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/16434984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histaminergic regulation of natural killer cell-mediated clearance of tumour cells in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16434984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remission maintenance therapy with histamine and interleukin-2 in acute myelogenous leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16434984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell-and natural killer cell-mediated cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16434984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant human interleukin-2, recombinant human interferon alfa-2a, or both in metastatic renal-cell carcinoma. Groupe Français d'Immunothérapie

1 reference

https://pubmed.ncbi.nlm.nih.gov/16434984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas Ligand Expression in Metastatic Renal Cell Carcinoma During Interleukin-2 Based Immunotherapy: No In vivo Effect of Fas Ligand Tumor Counterattack

1 reference

https://pubmed.ncbi.nlm.nih.gov/16434984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histamine protects T cells and natural killer cells against oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/16434984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJC.6602937

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16434984%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

release_ockdqv2oijfwvby5knzkc42pmq

1 reference

https://api.fatcat.wiki/v0/release/ockdqv2oijfwvby5knzkc42pmq

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16434984%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16434984%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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