Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: a HuGE review (Q36612606)

15 August 2017

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title

Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: a HuGE review (English)

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15 August 2017

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cardiovascular disease

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based on heuristic

inferred from title

author

Gianpiero L. Cavalleri

object named as

Gianpiero L Cavalleri

2

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Aroon Hingorani

6

object named as

Aroon D Hingorani

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15 August 2017

4

Liam Smeeth

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15 August 2017

Juan P Casas

1

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15 August 2017

Leonelo E Bautista

3

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15 August 2017

Steve E Humphries

5

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15 August 2017

language of work or name

English

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publication date

3 October 2006

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American Journal of Epidemiology

15 August 2017

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15 August 2017

164

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15 August 2017

10

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15 August 2017

921-935

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Structure-function aspects in the nitric oxide synthases

15 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Polymorphisms in endothelial nitric oxide synthase and atherogenesis: John French Lecture 2000.

21 January 2018

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Biosynthesis and action of nitric oxide in mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Enzymatic function of nitric oxide synthases

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Expression of human nitric oxide synthase isozymes

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endogenous Dimethylarginine as an Inhibitor of Nitric Oxide Synthesis

21 January 2018

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The L-arginine-nitric oxide pathway

21 January 2018

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Endothelium-dependent dilatation is impaired in young healthy subjects with a family history of premature coronary disease.

21 January 2018

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Effects of ethnicity on the distribution of clinically relevant endothelial nitric oxide variants

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase genotype and ischemic heart disease: meta-analysis of 26 studies involving 23028 subjects

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial NO synthase genotype and risk of preeclampsia: a multicenter case-control study

21 January 2018

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Pharmacogenetics in the laboratory and the clinic.

21 January 2018

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Genetic and environmental determinants of plasma nitrogen oxides and risk of ischemic heart disease

21 January 2018

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Selection and evaluation of tagging SNPs in the neuronal-sodium-channel gene SCN1A: implications for linkage-disequilibrium gene mapping

21 January 2018

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Intracellular processing of endothelial nitric oxide synthase isoforms associated with differences in severity of cardiopulmonary diseases: cleavage of proteins with aspartate vs. glutamate at position 298.

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Modifier effect of ENOS in autosomal dominant polycystic kidney disease.

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Functional characterization of Glu298Asp mutant human endothelial nitric oxide synthase purified from a yeast expression system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Functional comparison of the endothelial nitric oxide synthase Glu298Asp polymorphic variants in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Acidic hydrolysis as a mechanism for the cleavage of the Glu(298)-->Asp variant of human endothelial nitric-oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial function and carotid intima-media thickness in young healthy subjects among endothelial nitric oxide synthase Glu298-->Asp and T-786-->C polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Relation of endothelial nitric oxide synthase gene to plasma nitric oxide level, endothelial function, and blood pressure in African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Replication protein A1 reduces transcription of the endothelial nitric oxide synthase gene containing a -786T-->C mutation associated with coronary spastic angina.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

T-786-->C mutation in the 5'-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Shear stress insensitivity of endothelial nitric oxide synthase expression as a genetic risk factor for coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

The T-786C and Glu298Asp polymorphisms of the endothelial nitric oxide gene affect the forearm blood flow responses of Caucasian hypertensive patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase gene polymorphism, homocysteine, cholesterol and vascular endothelial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke: 2002 Update: Consensus Panel Guide to Comprehensive Risk Reduction for Adult Patients Without Coronary or Other Atherosclerotic Vascular Diseases. American Heart Association

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Infections and atherosclerosis: new clues from an old hypothesis?

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Markers of inflammation and cardiovascular disease: application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Problems of reporting genetic associations with complex outcomes

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Meta-analysis in clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Polymorphisms of the endothelial nitric oxide synthase gene - no consistent association with myocardial infarction in the ECTIM study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Genetic factors associated with endothelial dysfunction affect the early onset of coronary artery disease in Korean males

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Aging affects the association between endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction in the Korean male population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Lack of association of the Glu298Asp polymorphism of endothelial nitric oxide synthase with manifest coronary artery disease, carotid atherosclerosis and forearm vascular reactivity in two Austrian populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

The T-786C endothelial nitric oxide synthase genotype is a novel risk factor for coronary artery disease in Caucasian patients of the GENICA study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

NO level and endothelial NO synthase gene polymorphism (Glu298Asp) in the patients with coronary artery disease from the Turkish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

An integrated evaluation of endothelial constitutive nitric oxide synthase polymorphisms and coronary artery disease in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

The eNOS gene polymorphism does not have a major impact on lipid parameters and premature coronary artery disease in Caucasian women

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Association of endothelial constitutive nitric oxide synthase gene polymorphism with acute coronary syndrome in Koreans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Genotypes and haplotypes predisposing to myocardial infarction: a multilocus case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase gene is associated with vessel stenosis in Korean population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Prediction of the risk of myocardial infarction from polymorphisms in candidate genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Relationship of eNOS gene variants to diseases that have in common an endothelial cell dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

eNOS gene intron 4 a/b VNTR polymorphism is a risk factor for coronary artery disease in Southern Turkey.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Hyperhomocysteinemia, endothelial nitric oxide synthase polymorphism, and risk of coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

The GLU298ASP variant of nitric oxide synthase interacts with asymmetric dimethyl arginine in determining cardiovascular mortality in patients with end-stage renal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Haplotype analysis of the endothelial nitric oxide synthase gene in relation to acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase G894T gene polymorphism in Chilean subjects with coronary artery disease and controls.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Evidence for association of a common variant of the endothelial nitric oxide synthase gene (Glu298-->Asp polymorphism) to the presence, extent, and severity of coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

The G894T polymorphism on endothelial nitric oxide synthase gene is associated with premature coronary artery disease in a Turkish population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Association between ENOS gene polymorphism and cardiovascular events in nondiabetic hemodialysis patients: a prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

'Racial' differences in genetic effects for complex diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Lack of evidence for linkage of the endothelial cell nitric oxide synthase gene to essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Genome-wide linkage analysis of systolic and diastolic blood pressure: the Québec Family Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Combined effects of endothelial nitric oxide synthase gene polymorphism (G894T) and insulin resistance status on blood pressure and familial risk of hypertension in young adults: the Bogalusa Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Association analyses of endothelial nitric oxide synthase gene polymorphisms in essential hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase gene Glu298Asp polymorphism and blood pressure, left ventricular mass and carotid artery atherosclerosis in a population-based cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Association of the Glu298Asp polymorphism in the endothelial nitric oxide synthase gene with essential hypertension resistant to conventional therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase gene is positively associated with essential hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Peroxisome proliferator-activated receptor-gamma2-Pro12Ala and endothelial nitric oxide synthase-4a/bgene polymorphisms are associated with essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase Glu298Asp gene polymorphism, blood pressure and hypertension in a general population sample

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase polymorphisms and hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and development of pre-eclampsia: a case-control study and a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Angiotensinogen and endothelial nitric oxide synthase gene polymorphisms among Hispanic patients with preeclampsia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls.

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase gene interactions and the risk of ischaemic stroke

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide gene haplotypes and risk of cerebral small-vessel disease.

21 January 2018

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Association of a 27-bp repeat polymorphism in ecNOS gene with ischemic stroke in Chinese patients.

21 January 2018

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Cryptogenic stroke in relation to genetic variation in clotting factors and other genetic polymorphisms among young men and women

21 January 2018

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Promoter polymorphisms in the nitric oxide synthase 3 gene are associated with ischemic stroke susceptibility in young black women

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Association of (-)786T-C mutation of endothelial nitric oxide synthase gene with insulin resistance

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase (ecNOS) 4 a/b gene polymorphism and carotid artery intima-media thickness in type-1 diabetic patients.

21 January 2018

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Endothelial nitric oxide synthase exon 7 polymorphism, ischemic cerebrovascular disease, and carotid atheroma.

21 January 2018

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A common variant of endothelial nitric oxide synthase (Glu298Asp) is an independent risk factor for carotid atherosclerosis.

21 January 2018

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Synergistic interaction of T???786???C polymorphism in the endothelial nitric oxide synthase gene and smoking for an enhanced risk for coronary spasm

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Candidate genetic markers and the risk of restenosis after coronary angioplasty

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

The Glu298Asp polymorphism in endothelial nitric oxide synthase gene is associated with coronary in-stent restenosis

21 January 2018

1 reference

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Lack of association between polymorphisms of catalase, copper-zinc superoxide dismutase (SOD), extracellular SOD and endothelial nitric oxide synthase genes and macroangiopathy in patients with type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase polymorphisms are associated with type 2 diabetes and the insulin resistance syndrome.

21 January 2018

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Association of a 27-bp repeat polymorphism in intron 4 of endothelial constitutive nitric oxide synthase gene with serum uric acid levels in chinese subjects with type 2 diabetes

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase gene and the development of diabetic nephropathy

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Association of eNOS Glu298Asp polymorphism with end-stage renal disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

The ENOS polymorphism is not associated with severity of renal disease in polycystic kidney disease 1.

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase gene polymorphisms in Behcet's disease and rheumatic diseases with vasculitis

21 January 2018

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Improving the prediction of complex diseases by testing for multiple disease-susceptibility genes

21 January 2018

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Revisiting the clinical validity of multiplex genetic testing in complex diseases

21 January 2018

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Primary Prevention of Ischemic Stroke

21 January 2018

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Assessment of frequency of progression to hypertension in non-hypertensive participants in the Framingham Heart Study: a cohort study

21 January 2018

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Genomewide Linkage Scan of Resting Blood Pressure

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Endothelial nitric oxide synthase Glu298→Asp polymorphism, carotid atherosclerosis and intima-media thickness in a general population sample

21 January 2018

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https://api.crossref.org/works/10.1093%2FAJE%2FKWJ302

Genome scans and candidate gene approaches in the study of common diseases and variable drug responses

21 January 2018

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Trends in prevalence, awareness, treatment, and control of hypertension in the United States, 1988-2000.

21 January 2018

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28 May 2022

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Identifiers

DOI

10.1093/AJE/KWJ302

1 reference

15 August 2017

1 reference