Problems of reporting genetic associations with complex outcomes (Q34184173)

31 July 2017

title

Problems of reporting genetic associations with complex outcomes (English)

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31 July 2017

3

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31 July 2017

Helen M Colhoun

1

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author name string

Paul M McKeigue

series ordinal

2

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31 July 2017

publication date

1 March 2003

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31 July 2017

language of work or name

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31 July 2017

volume

361

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31 July 2017

issue

9360

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31 July 2017

page(s)

865-872

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publication type of scholarly work

31 July 2017

review article

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Replication validity of genetic association studies

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Parameters for reliable results in genetic association studies in common disease

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Polymorphisms of alpha-adducin and salt sensitivity in patients with essential hypertension

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Association of the alpha-adducin locus with essential hypertension

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Alpha-adducin gene polymorphism and cardiovascular phenotypes in a general population

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Human α-Adducin Gene, Blood Pressure, and Sodium Metabolism

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No Association Between α-Adducin 460 Polymorphism and Essential Hypertension in a Japanese Population

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Lack of Association Between the α-Adducin Locus and Essential Hypertension in the Japanese Population

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Lack of association between a biallelic polymorphism in the adducin gene and blood pressure in whites and African Americans

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Association and linkage analysis of the alpha-adducin gene and blood pressure

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Lack of evidence for an association between alpha-adducin and blood pressure regulation in Asian populations.

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All for one and one for all: introduction to a coordinated analysis of the Gly-460-Trp alpha-adducin polymorphism

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Association study designs for complex diseases

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Association studies of genetic polymorphisms and complex disease

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Maneuvering in the complex path from genotype to phenotype

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Putting the search for genes in perspective

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Trials of the beta model for complex inheritance

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Linkage disequilibrium mapping of complex disease: fantasy or reality?

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On the allelic spectrum of human disease

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Association and linkage analysis of alpha-adducin polymorphism: is the glass half full or half empty?

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The replication requirement

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Global patterns of linkage disequilibrium at the CD4 locus and modern human origins

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Linkage disequilibrium in the human genome

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The Frequent 5,10-Methylenetetrahydrofolate Reductase C677T Polymorphism Is Associated with a Common Haplotype in Whites, Japanese, and Africans

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Epidemiological methods for studying genes and environmental factors in complex diseases

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Tests and estimates of allelic association in complex inheritance

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Patterns of linkage disequilibrium in the human genome

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7 January 2021

Reporting, appraising, and integrating data on genotype prevalence and gene-disease associations

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Population stratification in epidemiologic studies of common genetic variants and cancer: quantification of bias

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Association mapping in structured populations

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The future of genetic studies of complex human diseases

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Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis

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MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.

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Large-scale test of hypothesised associations between the angiotensin-converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls. International Studies of Infarct Survival (ISIS) Collaborators

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Large upward bias in estimation of locus-specific effects from genomewide scans

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A meta-analysis of the association of the deletion allele of the angiotensin-converting enzyme gene with myocardial infarction

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The deletion/insertion polymorphism of the angiotensin converting enzyme gene and cardiovascular-renal risk

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ACE gene polymorphism in cardiovascular disease: meta-analyses of small and large studies in whites

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7 January 2021

Where now for meta-analysis?

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Bias in meta-analysis detected by a simple, graphical test

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Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

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Genetic Polymorphisms and Disease

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p values, hypothesis tests, and likelihood: implications for epidemiology of a neglected historical debate

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Sifting the evidence-what's wrong with significance tests?

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Haplotype tagging for the identification of common disease genes

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On the relative sample size required for multiple comparisons

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MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial

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Identifiers

DOI

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31 July 2017

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