Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia (Q36600942)

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scientific article published on 21 September 2006

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English	Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia	scientific article published on 21 September 2006

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia (English)

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Europe PubMed Central

15 August 2017

author name string

Pedersen-Bjergaard J

1

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Europe PubMed Central

15 August 2017

Christiansen DH

2

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Europe PubMed Central

15 August 2017

Desta F

3

1 reference

Europe PubMed Central

15 August 2017

Andersen MK

4

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Europe PubMed Central

15 August 2017

language of work or name

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publication date

21 September 2006

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Europe PubMed Central

15 August 2017

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Europe PubMed Central

15 August 2017

20

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Europe PubMed Central

15 August 2017

1943-1949

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Europe PubMed Central

15 August 2017

11

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Europe PubMed Central

15 August 2017

https://scigraph.springernature.com/pub.10.1038/sj.leu.2404381

0 references

Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461)

1 reference

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Pooled analysis of clinical and cytogenetic features in treatment-related and de novo adult acute myeloid leukemia and myelodysplastic syndromes based on a consecutive series of 761 patients analyzed 1976-1993 and on 5098 unselected cases reported i

1 reference

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21 January 2018

Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: the University of Chicago series.

1 reference

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21 January 2018

Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia

1 reference

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21 January 2018

Cooperativity between mutations in tyrosine kinases and in hematopoietic transcription factors in AML.

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21 January 2018

Genetics of myeloid leukemias

1 reference

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21 January 2018

Mutations of AML1 are common in therapy-related myelodysplasia following therapy with alkylating agents and are significantly associated with deletion or loss of chromosome arm 7q and with subsequent leukemic transformation

1 reference

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21 January 2018

Mutations of genes in the receptor tyrosine kinase (RTK)/RAS-BRAF signal transduction pathway in therapy-related myelodysplasia and acute myeloid leukemia.

1 reference

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Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia.

1 reference

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Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia.

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Secondary acute myeloid leukemia in children treated for acute lymphoid leukemia

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11q23 balanced chromosome aberrations in treatment-related myelodysplastic syndromes and acute leukemia: report from an international workshop

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Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes

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Activating mutations of RTK/ras signal transduction pathway in pediatric acute myeloid leukemia

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RAS mutation in acute myeloid leukemia is associated with distinct cytogenetic subgroups but does not influence outcome in patients younger than 60 years

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Therapy-related acute myeloid leukemia with t(8;21), inv(16), and t(8;16): a report on 25 cases and review of the literature

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21q22 balanced chromosome aberrations in therapy-related hematopoietic disorders: report from an international workshop

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DNA topoisomerase II in therapy-related acute promyelocytic leukemia.

1 reference

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The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the Unite

1 reference

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Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis

1 reference

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21 January 2018

Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

21 January 2018

The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9

1 reference

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21 January 2018

A gain-of-function mutation of JAK2 in myeloproliferative disorders

1 reference

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The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and myelodysplastic syndromes

1 reference

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21 January 2018

Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

21 January 2018

Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

21 January 2018

DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

21 January 2018

Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia.

1 reference

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21 January 2018

FLT3 and MLL intragenic abnormalities in AML reflect a common category of genotoxic stress.

1 reference

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21 January 2018

Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

1 reference

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Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis

1 reference

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Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia

1 reference

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FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia.

1 reference

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21 January 2018

Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor progno

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

based on heuristic

inferred from DOI database lookup

Internal tandem duplications of the FLT3 and MLL genes are mainly observed in atypical cases of therapy-related acute myeloid leukemia with a normal karyotype and are unrelated to type of previous therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

based on heuristic

inferred from DOI database lookup

Activating mutations of JAK2V617F are uncommon in t-MDS and t-AML and are only observed in atypic cases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

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inferred from DOI database lookup

Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia

1 reference

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7 January 2021

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Centromeric breakage and highly rearranged chromosome derivatives associated with mutations of TP53 are common in therapy-related MDS and AML after therapy with alkylating agents: an M-FISH study

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Duplication or amplification of chromosome band 11q23, including the unrearranged MLL gene, is a recurrent abnormality in therapy-related MDS and AML, and is closely related to mutation of the TP53 gene and to previous therapy with alkylating agents

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML

1 reference

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7 January 2021

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Secondary acute leukemia and myelodysplastic syndrome with 11q23 abnormalities. EU Concerted Action 11q23 Workshop

1 reference

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7 January 2021

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Balanced chromosome aberrations in leukemias following chemotherapy with DNA-topoisomerase II inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

based on heuristic

inferred from DOI database lookup

c-kit proto-oncogene exon 8 in-frame deletion plus insertion mutations in acute myeloid leukaemia

1 reference

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7 January 2021

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Incidence and prognosis of c-KIT and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

based on heuristic

inferred from DOI database lookup

Therapy-related acute promyelocytic leukemia: a report on 16 cases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

based on heuristic

inferred from DOI database lookup

Increase therapy-related leukemia secondary to breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

based on heuristic

inferred from DOI database lookup

Screening for MLL tandem duplication in 387 unselected patients with AML identify a prognostically unfavorable subset of AML

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

based on heuristic

inferred from DOI database lookup

Insights into leukemogenesis from therapy-related leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

based on heuristic

inferred from DOI database lookup

Potential role for DNA topoisomerase II poisons in the generation of t(11;20)(p15;q11) translocations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.LEU.2404381

1 reference

Europe PubMed Central

15 August 2017

release_lc4efralxzgz7ijtj2jysvvaay

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https://api.fatcat.wiki/v0/release/lc4efralxzgz7ijtj2jysvvaay

24 November 2022

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mapped directly with Wikidata item

1 reference

Europe PubMed Central

15 August 2017

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