The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9 (Q24317238)

multicellular organism development

GOA release 2020-03-11

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GOA release 2020-03-11

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J Rowley

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author name string

J Borrow

1

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A M Shearman

2

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V P Stanton

3

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R Becher

4

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T Collins

5

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A J Williams

6

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I Dubé

7

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F Katz

8

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Y L Kwong

9

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C Morris

10

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K Ohyashiki

11

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K Toyama

12

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D E Housman

https://scigraph.springernature.com/pub.10.1038/ng0296-159

14

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language of work or name

English

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publication date

February 1996

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published in

Nature Genetics

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volume

12

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page(s)

159-67

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issue

2

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exact match

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Two additional cases of acute myeloid leukemia with t(7;11)(p15;p15) having low neutrophil alkaline phosphatase scores

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HRAS1 and INS genes are relocated but not structurally altered as a result of the t(7;11) (p15;p15) in a clone from a patient with acute myeloid leukaemia (M4)

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Deregulation of a Homeobox Gene, HOX11, by the t(10;14) in T Cell Leukemia

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The human CAN protein, a putative oncogene product associated with myeloid leukemogenesis, is a nuclear pore complex protein that faces the cytoplasm

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The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex

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