C-terminal turn stability determines assembly differences between Aβ40 and Aβ42 (Q36517962)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23154165%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

title

C-terminal turn stability determines assembly differences between Aβ40 and Aβ42 (English)

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18 February 2020

5

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18 February 2020

7

George B Benedek

1 reference

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18 February 2020

author name string

Robin Roychaudhuri

1

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18 February 2020

Mingfeng Yang

2

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18 February 2020

Atul Deshpande

3

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18 February 2020

Gregory M Cole

4

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18 February 2020

Aleksey Lomakin

6

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18 February 2020

David B Teplow

8

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18 February 2020

language of work or name

English

0 references

publication date

12 November 2012

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Journal of Molecular Biology

18 February 2020

published in

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18 February 2020

volume

425

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18 February 2020

issue

2

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18 February 2020

page(s)

292-308

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Atomic View of a Toxic Amyloid Small Oligomer

18 February 2020

cites work

1 reference

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Rationally designed turn promoting mutation in the amyloid-β peptide sequence stabilizes oligomers in solution

30 September 2017

1 reference

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Structural evolution of Iowa mutant β-amyloid fibrils from polymorphic to homogeneous states under repeated seeded growth

30 September 2017

1 reference

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Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

30 September 2017

1 reference

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Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils

30 September 2017

1 reference

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Structure-neurotoxicity relationships of amyloid beta-protein oligomers

30 September 2017

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Binding mode of Thioflavin T and other molecular probes in the context of amyloid fibrils-current status

30 September 2017

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Simulating oligomerization at experimental concentrations and long timescales: A Markov state model approach

30 September 2017

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Amyloid beta-protein assembly and Alzheimer disease

30 September 2017

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Amyloid beta-protein monomer folding: free-energy surfaces reveal alloform-specific differences

30 September 2017

1 reference

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Structure and dynamics of the Abeta(21-30) peptide from the interplay of NMR experiments and molecular simulations

30 September 2017

1 reference

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p21-activated kinase-aberrant activation and translocation in Alzheimer disease pathogenesis

30 September 2017

1 reference

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Conformational properties of the Pro-Gly motif in the D-Ala-l-Pro-Gly-D-Ala model peptide explored by a statistical analysis of the NMR, Raman, and Raman optical activity spectra

30 September 2017

1 reference

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Familial Alzheimer's disease mutations alter the stability of the amyloid beta-protein monomer folding nucleus

30 September 2017

1 reference

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The Alzheimer's peptides Abeta40 and 42 adopt distinct conformations in water: a combined MD / NMR study

30 September 2017

1 reference

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Comparison of multiple Amber force fields and development of improved protein backbone parameters

30 September 2017

1 reference

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A specific amyloid-beta protein assembly in the brain impairs memory

30 September 2017

1 reference

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Quasielastic light scattering study of amyloid beta-protein fibril formation

30 September 2017

1 reference

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Solvent and mutation effects on the nucleation of amyloid beta-protein folding

30 September 2017

1 reference

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3D structure of Alzheimer's amyloid-beta(1-42) fibrils

30 September 2017

1 reference

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Quasielastic light scattering for protein assembly studies.

30 September 2017

1 reference

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Protein folding: the stepwise assembly of foldon units

30 September 2017

1 reference

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Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

30 September 2017

1 reference

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In silico study of amyloid beta-protein folding and oligomerization

30 September 2017

1 reference

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DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540122

Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways

30 September 2017

1 reference

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A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

30 September 2017

1 reference

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Probing the structural determinants of type II' beta-turn formation in peptides and proteins

30 September 2017

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Amyloid beta-protein oligomerization: prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins

30 September 2017

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Alzheimer's disease: genes, proteins, and therapy

30 September 2017

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Generalized born models of macromolecular solvation effects

30 September 2017

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Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease

30 September 2017

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Chemistry for the analysis of protein-protein interactions: rapid and efficient cross-linking triggered by long wavelength light

30 September 2017

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Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

30 September 2017

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Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

30 September 2017

1 reference

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Foldons, protein structural modules, and exons

30 September 2017

1 reference

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On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants

30 September 2017

1 reference

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The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540122

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540122

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

30 September 2017

1 reference

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The molecular pathology of Alzheimer's disease

30 September 2017

1 reference

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On the nucleation of amyloid beta-protein monomer folding

30 September 2017

1 reference

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An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

28 June 2018

1 reference

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Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

28 June 2018

1 reference

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Antiparallel beta-sheet: a signature structure of the oligomeric amyloid beta-peptide

28 June 2018

1 reference

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Abeta42 is more rigid than Abeta40 at the C terminus: implications for Abeta aggregation and toxicity.

21 September 2018

1 reference

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The conformations of the amyloid-beta (21-30) fragment can be described by three families in solution

21 September 2018

1 reference

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Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.

21 September 2018

1 reference

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Structure of the 21-30 fragment of amyloid beta-protein.

21 September 2018

1 reference

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Formation and stabilization model of the 42-mer Abeta radical: implications for the long-lasting oxidative stress in Alzheimer's disease

21 September 2018

1 reference

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Rapid photochemical cross-linking--a new tool for studies of metastable, amyloidogenic protein assemblies

21 September 2018

1 reference

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Solution NMR studies of the A beta(1-40) and A beta(1-42) peptides establish that the Met35 oxidation state affects the mechanism of amyloid formation

21 September 2018

1 reference

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Elucidation of primary structure elements controlling early amyloid beta-protein oligomerization.

21 September 2018

1 reference

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Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

21 September 2018

1 reference

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Spontaneous in vitro formation of supramolecular beta-amyloid structures, "betaamy balls", by beta-amyloid 1-40 peptide

21 September 2018

1 reference

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A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

21 September 2018

1 reference

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Comparison of the LDH and MTT assays for quantifying cell death: validity for neuronal apoptosis?

21 September 2018

1 reference

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Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540122

Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).

21 September 2018

1 reference

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Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23154165

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.JMB.2012.11.006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23154165%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23154165%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23154165%20AND%20SRC:MED&resulttype=core&format=json