Progressive dopamine neuron loss in Parkinson's disease: the multiple hit hypothesis (Q36485934)

14 August 2017

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title

Progressive dopamine neuron loss in Parkinson's disease: the multiple hit hypothesis (English)

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14 August 2017

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Paul M Carvey

1

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PubMed ID

16719059

14 August 2017

Ashok Punati

series ordinal

2

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PubMed ID

16719059

14 August 2017

Mary B Newman

series ordinal

3

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14 August 2017

1 January 2006

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14 August 2017

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14 August 2017

15

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14 August 2017

3

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14 August 2017

239-250

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Chronic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine to monkeys: behavioural, morphological and biochemical correlates.

14 August 2017

1 reference

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Striatal dopaminergic denervation in early and late onset Parkinson's disease assessed by PET and the tracer [11C]FECIT: preliminary findings in one patient with autosomal recessive parkinsonism (Park2).

21 January 2018

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Comparative behavioral, biochemical and pigmentary effects of MPTP, MPP+ and paraquat in Rana pipiens.

21 January 2018

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A fetal risk factor for Parkinson's disease

21 January 2018

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

21 January 2018

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Kinetics of nigral degeneration in a chronic model of MPTP-treated mice

21 January 2018

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A chronic MPTP model reproducing the slow evolution of Parkinson's disease: evolution of motor symptoms in the monkey.

21 January 2018

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Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

21 January 2018

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Combined PET/MRS brain studies show dynamic and long-term physiological changes in a primate model of Parkinson disease.

21 January 2018

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Aetiology of Parkinson's disease

21 January 2018

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3,4-Dihydroxyphenylalanine and 5-hydroxytryptophan as reserpine antagonists

21 January 2018

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Prenatal exposure to the bacteriotoxin lipopolysaccharide leads to long-term losses of dopamine neurons in offspring: a potential, new model of Parkinson's disease

21 January 2018

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Defining the ends of Parkin exon 4 deletions in two different families with Parkinson's disease

21 January 2018

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Striatal trophic factor activity in aging monkeys with unilateral MPTP-induced parkinsonism.

21 January 2018

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Paraquat: a useful tool for the in vivo study of mechanisms of neuronal cell death.

21 January 2018

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Diorthosubstituted polychlorinated biphenyls in caudate nucleus in Parkinson's disease.

21 January 2018

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Developmental pesticide models of the Parkinson disease phenotype

21 January 2018

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Developmental pesticide exposures and the Parkinson's disease phenotype

21 January 2018

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Modification of Parkinsonism--chronic treatment with L-dopa

21 January 2018

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The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease.

21 January 2018

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Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system

21 January 2018

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A Drosophila model of Parkinson's disease

21 January 2018

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Ageing and Parkinson's disease: substantia nigra regional selectivity

21 January 2018

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Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS manganese intoxication.

21 January 2018

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Pesticides and risk of Parkinson disease: a population-based case-control study

21 January 2018

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Survival of implanted fetal dopamine cells and neurologic improvement 12 to 46 months after transplantation for Parkinson's disease

21 January 2018

1 reference

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Sequential bilateral transplantation in Parkinson's disease: effects of the second graft.

21 January 2018

1 reference

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Neurochemical and histochemical characterization of neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on brain catecholamine neurones in the mouse.

21 January 2018

1 reference

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Parkinson's disease: interpretations of transplantation study are erroneous.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

Cell implantation therapies for Parkinson's disease using neural stem, transgenic or xenogeneic donor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

Inhibition of catecholamine uptake by 6-hydroxydopamine in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

Dieldrin-induced neurotoxicity: relevance to Parkinson's disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

Use of Rauwolfia serpentina Benth. in neuropsychiatric conditions.

21 January 2018

1 reference

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Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

21 January 2018

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Rotenone potentiates dopamine neuron loss in animals exposed to lipopolysaccharide prenatally

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

In utero bacterial endotoxin exposure causes loss of tyrosine hydroxylase neurons in the postnatal rat midbrain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

Combined toxicity of prenatal bacterial endotoxin exposure and postnatal 6-hydroxydopamine in the adult rat midbrain

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

Effects of paraquat on the substantia nigra of the wistar rats: neurochemical, histological, and behavioral studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

Environmental risk factors and Parkinson's disease: a case-control study in Taiwan

21 January 2018

1 reference

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Effects of locus coeruleus lesions on parkinsonian signs, striatal dopamine and substantia nigra cell loss after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in monkeys: a possible role for the locus coeruleus in the progression of Parkinson's disea

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease

21 January 2018

1 reference

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Potential environmental neurotoxins related to 1-methyl-4-phenylpyridinium: selective toxicity of 1-methyl-4-(4'-acetamidophenyl)-pyridinium and 1-methyl-4-cyclohexylpyridinium for dopaminergic neurons in culture

21 January 2018

1 reference

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Catechol compounds in rat tissues and in brains of different animals.

21 January 2018

1 reference

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Measuring the rate of progression and estimating the preclinical period of Parkinson's disease with [18F]dopa PET.

21 January 2018

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Multiple regions of alpha-synuclein are associated with Parkinson's disease

21 January 2018

1 reference

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Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.

21 January 2018

1 reference

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Fetal nigral transplantation as a therapy for Parkinson's disease

21 January 2018

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Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment

21 January 2018

1 reference

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

1 reference

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Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

21 January 2018

1 reference

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Striatal dopamine transporter function in dementia with Lewy bodies and Parkinson's disease

21 January 2018

1 reference

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Fate of nigrostriatal neurons in young mature mice given 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: a neurochemical and morphological reassessment.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

Toxicity of dieldrin for dopaminergic neurons in mesencephalic cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

The reaction sites of rotenone and ubiquinone with mitochondrial NADH dehydrogenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

Prevalence of parkin gene mutations and variations in idiopathic Parkinson's disease

21 January 2018

1 reference

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Pathological proteins in Parkinson's disease: focus on the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

Risk factors for dopaminergic neuron loss in human alpha-synuclein transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

6-hydroxy-dopamine induced degeneration of central monoamine neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

Effects of 6-hydroxydopamine on catecholamine containing neurones in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

Genetics of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F000000006783981990

10.3727/000000006783981990

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference

PubMed ID

16719059