Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration (Q36483438)

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English	Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration	scientific article

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration (English)

1 reference

Europe PubMed Central

14 August 2017

author name string

Hailiang Hu

1

1 reference

Europe PubMed Central

14 August 2017

Marc Milstein

2

1 reference

Europe PubMed Central

14 August 2017

Joanne M Bliss

3

1 reference

Europe PubMed Central

14 August 2017

Minh Thai

4

1 reference

Europe PubMed Central

14 August 2017

Gautam Malhotra

5

1 reference

Europe PubMed Central

14 August 2017

Lucia C Huynh

6

1 reference

Europe PubMed Central

14 August 2017

John Colicelli

7

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Europe PubMed Central

14 August 2017

language of work or name

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publication date

26 December 2007

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Europe PubMed Central

14 August 2017

Molecular and Cellular Biology

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Europe PubMed Central

14 August 2017

28

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Europe PubMed Central

14 August 2017

5

1 reference

Europe PubMed Central

14 August 2017

1573-1583

1 reference

Europe PubMed Central

14 August 2017

RIN1 is a breast tumor suppressor gene

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Defective TGF-beta signaling sensitizes human cancer cells to rapamycin

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Erbin inhibits transforming growth factor beta signaling through a novel Smad-interacting domain

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Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.

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Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation

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30 September 2017

Rin1 interacts with signal-transducing adaptor molecule (STAM) and mediates epidermal growth factor receptor trafficking and degradation

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30 September 2017

Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation.

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Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-beta signaling

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Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin

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30 September 2017

Endocytosis conducts the cell signaling orchestra

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30 September 2017

Vps9 domain-containing proteins: activators of Rab5 GTPases from yeast to neurons

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30 September 2017

Signaling and endocytosis: a team effort for cell migration

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The Snail genes as inducers of cell movement and survival: implications in development and cancer.

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CUTL1 is a target of TGF(beta) signaling that enhances cancer cell motility and invasiveness

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30 September 2017

RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration

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Met receptor dynamics and signalling.

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The role of internalization in transforming growth factor beta1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signaling in human mesangial cells

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Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

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Cytoplasmic PML function in TGF-beta signalling

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Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5.

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Met, metastasis, motility and more

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30 September 2017

TLP, a novel modulator of TGF-beta signaling, has opposite effects on Smad2- and Smad3-dependent signaling

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30 September 2017

A multigenic program mediating breast cancer metastasis to bone

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Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

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30 September 2017

The SRC homology 2 domain of Rin1 mediates its binding to the epidermal growth factor receptor and regulates receptor endocytosis

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Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.

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The RAS effector RIN1 modulates the formation of aversive memories

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Endocytosis of epidermal growth factor receptor regulated by Grb2-mediated recruitment of the Rab5 GTPase-activating protein RN-tre

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TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2

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Internalization-dependent and -independent requirements for transforming growth factor beta receptor signaling via the Smad pathway

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The RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.

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30 September 2017

Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1.

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TGF-beta signaling in tumor suppression and cancer progression

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Ski-interacting protein interacts with Smad proteins to augment transforming growth factor-beta-dependent transcription

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Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program

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Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

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ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors.

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https://pubmed.ncbi.nlm.nih.gov/18160707

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10.1128/MCB.01087-07

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Europe PubMed Central

14 August 2017

release_q5jocs6pn5g2vghxxez55kacha

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https://api.fatcat.wiki/v0/release/q5jocs6pn5g2vghxxez55kacha

24 November 2022

based on heuristic

mapped directly with Wikidata item

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Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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