Soluble biglycan: a potential mediator of cartilage degradation in osteoarthritis (Q36477482)

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3 March 2020

title

Soluble biglycan: a potential mediator of cartilage degradation in osteoarthritis (English)

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3 March 2020

1 reference

1 reference

Antti Soininen

2

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3 March 2020

Pekka Ylinen

3

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3 March 2020

Jerker Sandelin

4

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3 March 2020

Dan C Nordström

6

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3 March 2020

Kari K Eklund

7

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3 March 2020

publication date

24 December 2015

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Arthritis Research and Therapy

3 March 2020

published in

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3 March 2020

volume

17

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3 March 2020

page(s)

379

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describes a project that uses

3 March 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4718039/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/s13075-015-0902-0

0 references

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The role of small leucine-rich proteoglycans in osteoarthritis pathogenesis

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Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury.

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Biglycan induces the expression of osteogenic factors in human aortic valve interstitial cells via Toll-like receptor-2.

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Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21

30 September 2017

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Identification of a central role for complement in osteoarthritis

30 September 2017

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Proteases involved in cartilage matrix degradation in osteoarthritis.

30 September 2017

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Anabolic/Catabolic balance in pathogenesis of osteoarthritis: identifying molecular targets

30 September 2017

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The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis

30 September 2017

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A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis

30 September 2017

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Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors

30 September 2017

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Proprotein convertase activation of aggrecanases in cartilage in situ.

30 September 2017

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Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues

30 September 2017

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Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis

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30 September 2017

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Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis

30 September 2017

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30 September 2017

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Identification of a negative response element in the human inducible nitric-oxide synthase (hiNOS) promoter: The role of NF-kappa B-repressing factor (NRF) in basal repression of the hiNOS gene

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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21 September 2018

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21 September 2018

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The cleavage of biglycan by aggrecanases.

21 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718039

The catabolic pathway mediated by Toll-like receptors in human osteoarthritic chondrocytes.

21 September 2018

1 reference

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Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease-13: identification of a new biglycan cleavage site

21 September 2018

1 reference

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Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis

21 September 2018

1 reference

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Aggrecan protects cartilage collagen from proteolytic cleavage

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718039

The in situ up-regulation of chondrocyte interleukin-1-converting enzyme and interleukin-18 levels in experimental osteoarthritis is mediated by nitric oxide

21 September 2018

1 reference

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Osteoarthritis: priorities for osteoarthritis research: much to be done

21 September 2018

1 reference

12 December 2020

The small proteoglycans decorin and biglycan in human articular cartilage of late-stage osteoarthritis

1 reference

12 December 2020

Elevated levels of synovial fluid antibodies reactive with the small proteoglycans biglycan and decorin in patients with rheumatoid arthritis or other joint diseases

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12 December 2020

Rheumatoid synovitis. An extravascular immune complex disease

1 reference

12 December 2020

Light and electron microscopical immunohistochemical localization of the small proteoglycan core proteins decorin and biglycan in human knee joint cartilage

1 reference

12 December 2020

Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3

1 reference

12 December 2020

Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction

1 reference

12 December 2020

High mobility group box-1 (HMGB-1) in osteoarthritic cartilage

1 reference

12 December 2020

Toll-like receptors and chondrocytes: the lipopolysaccharide-induced decrease in cartilage matrix synthesis is dependent on the presence of toll-like receptor 4 and antagonized by bone morphogenetic protein 7

1 reference

12 December 2020

10.1186/S13075-015-0902-0

Identifiers

DOI

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Dimensions Publication ID

3 March 2020

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3 March 2020

PubMed publication ID

26703441

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26703441%20AND%20SRC:MED&resulttype=core&format=json