Lysophospholipids as mediators of immunity (Q36472040)

14 August 2017

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title

Lysophospholipids as mediators of immunity (English)

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14 August 2017

Debby A Lin

1

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PubMed ID

16682274

14 August 2017

Joshua A Boyce

series ordinal

2

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14 August 2017

1 January 2006

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14 August 2017

Advances in Immunology

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14 August 2017

89

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14 August 2017

141-167

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Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720

14 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Recombinant human G protein-coupled lysophosphatidic acid receptors mediate intracellular calcium mobilization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Serum lysophosphatidic acid is produced through diverse phospholipase pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Lysophosphatidic acid accelerates the development of human mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

FTY720 alters lymphocyte homing and protects allografts without inducing general immunosuppression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

The immune modulator FTY720 targets sphingosine 1-phosphate receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

FTY720, a novel immunosuppressant, induces sequestration of circulating lymphocytes by acceleration of lymphocyte homing

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Calcium mobilization via sphingosine kinase in signalling by the Fc epsilon RI antigen receptor

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone.

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Mature dendritic cell generation promoted by lysophosphatidylcholine

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Protein kinase Cdelta mediates lysophosphatidic acid-induced NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

p38 MAPK regulates group IIa phospholipase A2 expression in interleukin-1beta -stimulated rat neonatal cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Transduction of Multiple Effects of Sphingosine 1-Phosphate (S1P) on T Cell Functions by the S1P1 G Protein-Coupled Receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Expression of the lysophospholipid receptor family and investigation of lysophospholipid-mediated responses in human macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Local anesthetics attenuate lysophosphatidic acid-induced priming in human neutrophils

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Activation of human monocytic cells by lysophosphatidic acid and sphingosine-1-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

The sphingosine-1-phosphate (S1P) lysophospholipid receptor S1P3 regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Gelsolin binding and cellular presentation of lysophosphatidic acid

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Cutting edge: differential constitutive expression of functional receptors for lysophosphatidic acid by human blood lymphocytes

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Cutting edge: suppression of T cell chemotaxis by sphingosine 1-phosphate

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Protein kinase C epsilon dependence of the recovery from down-regulation of S1P1 G protein-coupled receptors of T lymphocytes

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Immunological effects of transgenic constitutive expression of the type 1 sphingosine 1-phosphate receptor by mouse lymphocytes

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

FTY720 suppresses humoral immunity by inhibiting germinal center reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Lysophosphatidic acid enhances in vivo infiltration and activation of guinea pig eosinophils and neutrophils via a Rho/Rho-associated protein kinase-mediated pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Human and rat alveolar macrophages express multiple EDG receptors

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokine-release in mature human dendritic cells for emergence of Th2 immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Lysophosphatidic acid induces chemotaxis, oxygen radical production, CD11b up-regulation, Ca2+ mobilization, and actin reorganization in human eosinophils via pertussis toxin-sensitive G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Characterization of a novel sphingosine 1-phosphate receptor, Edg-8

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Sphingosine 1-phosphate, a diffusible calcium influx factor mediating store-operated calcium entry.

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Lysophosphatidic acid triggers calcium entry through a non-store-operated pathway in human neutrophils

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Ceramide and sphingosine rapidly induce apoptosis of murine mast cells supported by interleukin-3 and stem cell factor

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Sphingosine 1-phosphate is a novel inhibitor of T-cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Lysophosphatidic acid induces human natural killer cell chemotaxis and intracellular calcium mobilization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Graft-versus-host disease can be separated from graft-versus-lymphoma effects by control of lymphocyte trafficking with FTY720.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Synthesis and immunosuppressive activity of 2-substituted 2-aminopropane-1,3-diols and 2-aminoethanols

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Sphingosine 1 phosphate induces the chemotaxis of human natural killer cells. Role for heterotrimeric G proteins and phosphoinositide 3 kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Attenuation of shock-induced acute lung injury by sphingosine kinase inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Lysophospholipid regulation of mononuclear phagocytes

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

IL-4 regulates MEK expression required for lysophosphatidic acid-mediated chemokine generation by human mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Cyclical modulation of sphingosine-1-phosphate receptor 1 surface expression during lymphocyte recirculation and relationship to lymphoid organ transit

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

G protein-coupled receptors in natural killer cells

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Sphingosine-1-phosphate phosphatases

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Dichotomy of Ca2+ signals triggered by different phospholipid pathways in antigen stimulation of human mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

A molecular switch changes the signalling pathway used by the Fc gamma RI antibody receptor to mobilise calcium

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Bioactive lysophospholipids and their G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

The immunomodulator FTY720 interferes with effector functions of human monocyte-derived dendritic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for the orphan receptor GPR63

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Identification of p2y9/GPR23 as a Novel G Protein-coupled Receptor for Lysophosphatidic Acid, Structurally Distant from the Edg Family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Molecular cloning of a novel putative G protein-coupled receptor expressed in the cardiovascular system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Sphingolipids and the balancing of immune cell function: lessons from the mast cell

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Sphingosine kinase: a mediator of vital cellular functions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Alpha2-adrenergic receptor-mediated release of lysophosphatidic acid by adipocytes: a paracrine signal for preadipocyte growth

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Lysophosphatidic acid synthesis and release

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

The influence of lysophosphatidic acid on the functions of human dendritic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

The balance between sphingosine and sphingosine-1-phosphate is decisive for mast cell activation after Fc epsilon receptor I triggering

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

G protein mediated signaling pathways in lysophospholipid induced cell proliferation and survival

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Growth factor-like action of lysophosphatidic acid on human B lymphoblasts.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Human eosinophil chemotaxis and selective in vivo recruitment by sphingosine 1-phosphate.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Inhibition of Th1- and Th2-mediated airway inflammation by the sphingosine 1-phosphate receptor agonist FTY720.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Lipid phosphate phosphatases regulate lysophosphatidic acid production and signaling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Sphingosine-1-phosphate: signaling inside and out.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Lysophosphatidic acid increases phosphatidic acid formation, phospholipase D activity and degranulation by human neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Homodimerization and heterodimerization of S1P/EDG sphingosine-1-phosphate receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Spider and bacterial sphingomyelinases D target cellular lysophosphatidic acid receptors by hydrolyzing lysophosphatidylcholine.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Physiological sphingosine 1-phosphate requirement for optimal activity of mouse CD4+ regulatory T Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Sphingosine 1-phosphate receptor agonists attenuate relapsing-remitting experimental autoimmune encephalitis in SJL mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Sphingosine-1-phosphate receptor agonism impairs the efficiency of the local immune response by altering trafficking of naive and antigen-activated CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Effect of lysophospholipids on signaling in the human Jurkat T cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Sphingosine 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

FTY720-enhanced T cell homing is dependent on CCR2, CCR5, CCR7, and CXCR4: evidence for distinct chemokine compartments

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Lysophosphatidic acid-induced Ca2+ mobilization requires intracellular sphingosine 1-phosphate production. Potential involvement of endogenous EDG-4 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Lysophosphatidic acid induces neointima formation through PPARgamma activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Altered expression and functional profile of lysophosphatidic acid receptors in mitogen-activated human blood T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Lysophosphatidic acid receptor-selective effects on Jurkat T cell migration through a Matrigel model basement membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2989004-2

7 January 2021

10.1016/S0065-2776(05)89004-2

Identifiers

DOI

1 reference

14 August 2017

1 reference

PubMed ID

16682274