Sphingosine kinase: a mediator of vital cellular functions (Q28185880)

Prostaglandins and Other Lipid Mediators

Europe PubMed Central

title

Sphingosine kinase: a mediator of vital cellular functions (English)

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author name string

A Olivera

series ordinal

1

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S Spiegel

series ordinal

2

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language of work or name

English

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publication date

April 2001

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published in

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volume

64

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issue

1-4

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page(s)

123-34

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cites work

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Sphingolipid long-chain-base auxotrophs of Saccharomyces cerevisiae: genetics, physiology, and a method for their selection

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De novo synthesis of sphingolipids is required for cell survival by down-regulating c-Jun N-terminal kinase in Drosophila imaginal discs

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A vital role for glycosphingolipid synthesis during development and differentiation

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7 January 2021

Specificity of inhibitors of serine palmitoyltransferase (SPT), a key enzyme in sphingolipid biosynthesis, in intact cells. A novel evaluation system using an SPT-defective mammalian cell mutant

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Functions of ceramide in coordinating cellular responses to stress

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Regulation of ceramide production and apoptosis

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Sphingolipid metabolites: members of a new class of lipid second messengers

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7 January 2021

Sphingolipid metabolites differentially regulate extracellular signal-regulated kinase and stress-activated protein kinase cascades

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7 January 2021

Bimodal regulation of ceramidase by interleukin-1beta. Implications for the regulation of cytochrome p450 2C11.

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Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells

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7 January 2021

Cell regulation by sphingosine and more complex sphingolipids

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7 January 2021

Biosynthesis of sphingolipids: dihydroceramide and not sphinganine is desaturated by cultured cells

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7 January 2021

Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis

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7 January 2021

Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival

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Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

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7 January 2021

Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation

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7 January 2021

Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation

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Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

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Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes

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Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction

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Tumor necrosis factor- induces adhesion molecule expression through the sphingosine kinase pathway

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7 January 2021

High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL

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7 January 2021

Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response.

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7 January 2021

Involvement of yeast sphingolipids in the heat stress response of Saccharomyces cerevisiae

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7 January 2021

Sphingolipids are potential heat stress signals in Saccharomyces

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7 January 2021

Calcium mobilization via sphingosine kinase in signalling by the Fc epsilon RI antigen receptor

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7 January 2021

Cell cycle control of PDGF-induced Ca(2+) signaling through modulation of sphingolipid metabolism

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7 January 2021

Calcium release-activated calcium current (ICRAC) is a direct target for sphingosine

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7 January 2021

The balance between sphingosine and sphingosine-1-phosphate is decisive for mast cell activation after Fc epsilon receptor I triggering

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7 January 2021

Sphingosine 1-phosphate: a prototype of a new class of second messengers.

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7 January 2021

Functions of a new family of sphingosine-1-phosphate receptors

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7 January 2021

Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate.

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7 January 2021

Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors

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7 January 2021

Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants

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7 January 2021

The DPL1 gene is involved in mediating the response to nutrient deprivation in Saccharomyces cerevisiae

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7 January 2021

Analysis of phosphorylated sphingolipid long-chain bases reveals potential roles in heat stress and growth control in Saccharomyces.

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7 January 2021

Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

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7 January 2021

Role of sphingosine kinase in Ca(2+) signalling by epidermal growth factor receptor

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7 January 2021

FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking

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7 January 2021

Lysophosphatidic acid-mediated Ca2+ mobilization in human SH-SY5Y neuroblastoma cells is independent of phosphoinositide signalling, but dependent on sphingosine kinase activation.

1 reference

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7 January 2021

Formyl peptide receptor signaling in HL-60 cells through sphingosine kinase

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7 January 2021

Evidence for the presence of multiple forms of Sph kinase in human platelets

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7 January 2021

Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

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7 January 2021

Regulatory effect of phorbol esters on sphingosine kinase in BALB/C 3T3 fibroblasts (variant A31): demonstration of cell type-specific response--a preliminary note

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7 January 2021

Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity

1 reference

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7 January 2021

Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900108-3

7 January 2021

Platelet-derived growth factor-induced activation of sphingosine kinase requires phosphorylation of the PDGF receptor tyrosine residue responsible for binding of PLCgamma

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900108-3

7 January 2021

Purification and characterization of rat kidney sphingosine kinase

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https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900108-3

7 January 2021

Molecular cloning and functional characterization of murine sphingosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900108-3

7 January 2021

The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900108-3

7 January 2021

Synthesis and evaluation of a photolyzable derivative of sphingosine 1-phosphate--caged SPP.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900108-3

7 January 2021

Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900108-3

7 January 2021

Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900108-3

7 January 2021

The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1-phosphate lyase

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https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900108-3

7 January 2021

Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast

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https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900108-3

7 January 2021

Identification of a Saccharomyces gene, LCB3, necessary for incorporation of exogenous long chain bases into sphingolipids

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900108-3

7 January 2021

Identification and characterization of Saccharomyces cerevisiae dihydrosphingosine-1-phosphate phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900108-3

7 January 2021

Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900108-3

7 January 2021

10.1016/S0090-6980(01)00108-3

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

11324702

1 reference

Consolidated OpenCitations Corpus – April 2017