Patched, the receptor of Hedgehog, is a lipoprotein receptor (Q36458834)

14 August 2017

Patched, the receptor of Hedgehog, is a lipoprotein receptor (English)

1 reference

14 August 2017

1 reference

GOA release 2020-03-11

Hedgehog Dmel_CG4637

1 reference

Apolipophorin Dmel_CG11064

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Ainhoa Callejo

1

1 reference

14 August 2017

Joaquim Culi

series ordinal

2

1 reference

14 August 2017

Isabel Guerrero

series ordinal

3

1 reference

14 August 2017

language of work or name

English

0 references

publication date

15 January 2008

1 reference

Proceedings of the National Academy of Sciences of the United States of America

14 August 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

14 August 2017

105

1 reference

14 August 2017

3

1 reference

14 August 2017

912-917

1 reference

A conserved mechanism of Hedgehog gradient formation by lipid modifications

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Orchestrating ontogenesis: variations on a theme by sonic hedgehog

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Mechanisms of Hedgehog gradient formation and interpretation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Lipoprotein particles are required for Hedgehog and Wingless signalling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Novel lipid modifications of secreted protein signals

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

The cholesterol membrane anchor of the Hedgehog protein confers stable membrane association to lipid-modified proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Patched controls the Hedgehog gradient by endocytosis in a dynamin-dependent manner, but this internalization does not play a major role in signal transduction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Hedgehog signalling in cancer formation and maintenance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Alternative lipid mobilization: the insect shuttle system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Sonic hedgehog induces the segregation of patched and smoothened in endosomes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Megalin functions as an endocytic sonic hedgehog receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

The sterol-sensing domain: multiple families, a unique role?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Hedgehog signaling in animal development: paradigms and principles

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

A freely diffusible form of Sonic hedgehog mediates long-range signalling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

arrow encodes an LDL-receptor-related protein essential for Wingless signalling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Is dynamin a regular motor or a master regulator?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Dual roles for patched in sequestering and transducing Hedgehog

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Molecular characterization and developmental expression of a retinoid- and fatty acid-binding glycoprotein from Drosophila. A putative lipophorin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

The Drosophila segment polarity gene patched interacts with decapentaplegic in wing development.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Interaction of tyrosine-based sorting signals with clathrin-associated proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Mutations affecting segment number and polarity in Drosophila

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Hedgehog signaling plays a conserved role in inhibiting fat formation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Hedgehog acts as a somatic stem cell factor in the Drosophila ovary

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Diacylglycerol transport in the insect fat body: evidence of involvement of lipid droplets and the cytosolic fraction

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

The precursor protein of the structural apolipoproteins of lipophorin: cDNA and deduced amino acid sequence

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex.

28 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705603105

Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705603105

Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705603105

Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705603105

Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705603105

The Drosophila ortholog of the human Wnt inhibitor factor Shifted controls the diffusion of lipid-modified Hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705603105

Hedgehog lipid modifications are required for Hedgehog stabilization in the extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705603105

Temporal modulation of the Hedgehog morphogen gradient by a patched-dependent targeting to lysosomal compartment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705603105

Lipoprotein-heparan sulfate interactions in the Hh pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705603105

Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705603105

Gradient formation of the TGF-beta homolog Dpp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705603105

The sterol-sensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705603105

Control of fat storage by a Drosophila PAT domain protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705603105

Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242683

21 September 2018

Identifiers

DOI

10.1073/PNAS.0705603105

1 reference

14 August 2017

0 references

1 reference

14 August 2017

1 reference