Discovery of small-molecule inhibitors of the TLR1/TLR2 complex (Q36434517)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22969053%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Discovery of small-molecule inhibitors of the TLR1/TLR2 complex (English)

1 reference

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13 February 2020

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2

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13 February 2020

author name string

Kui Cheng

series ordinal

1

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13 February 2020

Shuting Zhang

series ordinal

3

1 reference

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13 February 2020

Hang Yin

series ordinal

4

1 reference

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13 February 2020

language of work or name

English

0 references

publication date

11 September 2012

1 reference

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Angewandte Chemie International Edition

13 February 2020

published in

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13 February 2020

volume

51

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13 February 2020

issue

49

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13 February 2020

page(s)

12246-12249

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Accessory molecules for Toll-like receptors and their function

13 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses

30 September 2017

1 reference

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Characterization of sparstolonin B, a Chinese herb-derived compound, as a selective Toll-like receptor antagonist with potent anti-inflammatory properties

30 September 2017

1 reference

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The structural biology of Toll-like receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Small-molecule inhibitors of the TLR3/dsRNA complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Discovery of a novel TLR2 signaling inhibitor with anti-viral activity

30 September 2017

1 reference

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

30 September 2017

1 reference

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Targeting Toll-like receptors: emerging therapeutics?

30 September 2017

1 reference

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Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Blocking TLR2 activity attenuates pulmonary metastases of tumor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.

30 September 2017

1 reference

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Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Toll-like receptors modulate adult hippocampal neurogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Pathogen recognition and innate immunity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Cancer prevention by tea polyphenols is linked to their direct inhibition of antiapoptotic Bcl-2-family proteins.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Simultaneously monitoring DNA binding and helicase-catalyzed DNA unwinding by fluorescence polarization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

The extracellular toll-like receptor 2 domain directly binds peptidoglycan derived from Staphylococcus aureus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Fluorometric measurement of nitrite/nitrate by 2,3-diaminonaphthalene.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Enzymatic synthesis of tea theaflavin derivatives and their anti-inflammatory and cytotoxic activities

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Molecular structure and antioxidant specificity of purpurogallin in three types of human cardiovascular cells.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510333

Toll signaling: the TIReless quest for specificity

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22969053

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Novel synthetic gluco-disaccharide RSCL-0409--a lipopolysaccharide-induced Toll-like receptor-mediated signalling antagonist

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22969053

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Simple synthetic toll-like receptor 2 ligands

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22969053

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/ANIE.201204910

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22969053%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22969053%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22969053%20AND%20SRC:MED&resulttype=core&format=json