A limited 4 Å radial displacement of the S4-S5 linker is sufficient for internal gate closing in Kv channels (Q36407991)

14 August 2017

A limited 4 Å radial displacement of the S4-S5 linker is sufficient for internal gate closing in Kv channels (English)

1 reference

14 August 2017

Simon Bernèche

4

0 references

Rikard Blunck

object named as

Rikard Blunck

5

0 references

author name string

Élise Faure

1

1 reference

14 August 2017

Greg Starek

2

1 reference

14 August 2017

Hugo McGuire

3

1 reference

14 August 2017

language of work or name

English

0 references

publication date

27 September 2012

1 reference

Journal of Biological Chemistry

14 August 2017

1 reference

14 August 2017

287

1 reference

14 August 2017

47

1 reference

14 August 2017

40091-40098

1 reference

All-atom empirical potential for molecular modeling and dynamics studies of proteins

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Mechanism of electromechanical coupling in voltage-gated potassium channels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Structural basis for gating charge movement in the voltage sensor of a sodium channel

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

In search of a consensus model of the resting state of a voltage-sensing domain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

An electrostatic potassium channel opener targeting the final voltage sensor transition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Calculation of the gating charge for the Kv1.2 voltage-activated potassium channel

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Transfer of ion binding site from ether-a-go-go to Shaker: Mg2+ binds to resting state to modulate channel opening

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

An intersubunit interaction between S4-S5 linker and S6 is responsible for the slow off-gating component in Shaker K+ channels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

CHARMM: the biomolecular simulation program

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Conformational changes and slow dynamics through microsecond polarized atomistic molecular simulation of an integral Kv1.2 ion channel

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Dynamic coupling of voltage sensor and gate involved in closed-state inactivation of kv4.2 channels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Fluorescence detection of the movement of single KcsA subunits reveals cooperativity.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Voltage-dependent K+ channel gating and voltage sensor toxin sensitivity depend on the mechanical state of the lipid membrane

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

S4-based voltage sensors have three major conformations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Removal of phospho-head groups of membrane lipids immobilizes voltage sensors of K+ channels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

In vivo measurement of intramolecular distances using genetically encoded reporters

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Inhibition of CFTR Cl- channel function caused by enzymatic hydrolysis of sphingomyelin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Distance measurements reveal a common topology of prokaryotic voltage-gated ion channels in the lipid bilayer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Scalable molecular dynamics with NAMD

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

K channel subconductance levels result from heteromeric pore conformations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Crystal structure of a mammalian voltage-dependent Shaker family K+ channel

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Detecting rearrangements of shaker and NaChBac in real-time with fluorescence spectroscopy in patch-clamped mammalian cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

An Implicit Membrane Generalized Born Theory for the Study of Structure, Stability, and Interactions of Membrane Proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Coupling between voltage sensors and activation gate in voltage-gated K+ channels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Principles and biophysical applications of lanthanide-based probes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Ion conduction pore is conserved among potassium channels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Structure of the KcsA channel intracellular gate in the open state

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Atomic scale movement of the voltage-sensing region in a potassium channel measured via spectroscopy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Shaker potassium channel gating. III: Evaluation of kinetic models for activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Voltage-sensing residues in the S4 region of a mammalian K+ channel

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Mechanism of voltage gating in potassium channels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Mode shift of the voltage sensors in Shaker K+ channels is caused by energetic coupling to the pore domain

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Lipoelectric modification of ion channel voltage gating by polyunsaturated fatty acids

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Polyunsaturated fatty acids and cerebrospinal fluid from children on the ketogenic diet open a voltage-gated K channel: a putative mechanism of antiseizure action

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Contribution of the S4 segment to gating charge in the Shaker K+ channel.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501078

Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel

28 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.415497

A gating model for the archeal voltage-dependent K(+) channel KvAP in DPhPC and POPE:POPG decane lipid bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.415497

New insights into endotoxin-induced activation of macrophages: involvement of a K+ channel in transmembrane signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.415497

Small vertical movement of a K+ channel voltage sensor measured with luminescence energy transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.415497

Thiol-reactive luminescent lanthanide chelates: part 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.415497

Enzymatic activation of voltage-gated potassium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.415497

Lipid-dependent gating of a voltage-gated potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.415497

Voltage sensor of Kv1.2: structural basis of electromechanical coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.415497

Phospholipids and the origin of cationic gating charges in voltage sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.415497

CHARMM-GUI: a web-based graphical user interface for CHARMM

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23019337

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Thiol-reactive luminescent chelates of terbium and europium

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23019337

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Electrostatic parameters of cationic liposomes commonly used for gene delivery as determined by 4-heptadecyl-7-hydroxycoumarin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23019337

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.415497

1 reference

14 August 2017

1 reference

14 August 2017

1 reference