Mechanism of voltage gating in potassium channels (Q42644041)

4 November 2017

Mechanism of voltage gating in potassium channels (English)

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4 November 2017

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3

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4 November 2017

5

Ron O Dror

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4 November 2017

Morten Ø Jensen

1

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4 November 2017

Vishwanath Jogini

series ordinal

2

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4 November 2017

Abba E Leffler

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4

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4 November 2017

David E Shaw

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6

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4 November 2017

language of work or name

English

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publication date

1 April 2012

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4 November 2017

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4 November 2017

336

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4 November 2017

229-233

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4 November 2017

6078

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A quantitative description of membrane current and its application to conduction and excitation in nerve

4 November 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Sensing voltage across lipid membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

The size of gating charge in wild-type and mutant Shaker potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Calibrated measurement of gating-charge arginine displacement in the KvAP voltage-dependent K+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Closing in on the resting state of the Shaker K(+) channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Ion channel voltage sensors: structure, function, and pathophysiology

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Functional analysis of Kv1.2 and paddle chimera Kv channels in planar lipid bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Alteration and restoration of K+ channel function by deletions at the N- and C-termini.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

K+ channels lacking the 'tetramerization' domain: implications for pore structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Coupled K+-water flux through the HERG potassium channel measured by an osmotic pulse method

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Principles of conduction and hydrophobic gating in K+ channels

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Solute inaccessible aqueous volume changes during opening of the potassium channel of the squid giant axon

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Voltage gating of Shaker K+ channels. The effect of temperature on ionic and gating currents

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

A Gating Charge Transfer Center in Voltage Sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Removal of phospho-head groups of membrane lipids immobilizes voltage sensors of K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Voltage sensitivity and gating charge in Shaker and Shab family potassium channels.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Resolving the gating charge movement associated with late transitions in K channel activation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

The crystal structure of a voltage-gated sodium channel

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

A role for hydrophobic residues in the voltage-dependent gating of Shaker K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Portability of paddle motif function and pharmacology in voltage sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Deconstructing voltage sensor function and pharmacology in sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Gating pore current in an inherited ion channelopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Voltage-sensing arginines in a potassium channel permeate and occlude cation-selective pores

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Ion permeation through a voltage- sensitive gating pore in brain sodium channels having voltage sensor mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Voltage-sensor mutations in channelopathies of skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Inferred motions of the S3a helix during voltage-dependent K+ channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Transmembrane movement of the shaker K+ channel S4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

The twisted ion-permeation pathway of a resting voltage-sensing domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Effect of sensor domain mutations on the properties of voltage-gated ion channels: molecular dynamics studies of the potassium channel Kv1.2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Molecular dynamics investigation of the ω-current in the Kv1.2 voltage sensor domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

A proton pore in a potassium channel voltage sensor reveals a focused electric field

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Atomic proximity between S4 segment and pore domain in Shaker potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

The lipid-protein interface of a Shaker K(+) channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Altered state dependence of c-type inactivation in the long and short forms of human Kv1.5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

All-atom empirical potential for molecular modeling and dynamics studies of proteins

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Extending the treatment of backbone energetics in protein force fields: limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Update of the CHARMM all-atom additive force field for lipids: validation on six lipid types

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

A fast SHAKE algorithm to solve distance constraint equations for small molecules in molecular dynamics simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Gaussian split Ewald: A fast Ewald mesh method for molecular simulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

The membrane potential and its representation by a constant electric field in computer simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

VMD: visual molecular dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Calculation of the gating charge for the Kv1.2 voltage-activated potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Imaging alpha-hemolysin with molecular dynamics: ionic conductance, osmotic permeability, and the electrostatic potential map

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Molecular dynamics with coupling to an external bath

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

Phospholipids and the origin of cationic gating charges in voltage sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1216533

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1216533

1 reference

4 November 2017

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