Molecular spectrum of KRAS, NRAS, BRAF and PIK3CA mutations in Chinese colorectal cancer patients: analysis of 1,110 cases (Q36393095)

13 August 2017

Molecular spectrum of KRAS, NRAS, BRAF and PIK3CA mutations in Chinese colorectal cancer patients: analysis of 1,110 cases (English)

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13 August 2017

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9 June 2020

author name string

Jing Zhang

1

1 reference

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9 June 2020

Jianming Zheng

2

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9 June 2020

Yinghong Yang

3

1 reference

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9 June 2020

Junliang Lu

4

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9 June 2020

Jie Gao

5

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9 June 2020

Tao Lu

6

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9 June 2020

Hui Jiang

8

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9 June 2020

Yan Zhu

9

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9 June 2020

Yuhui Zheng

10

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9 June 2020

Zhiyong Liang

11

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9 June 2020

Tonghua Liu

12

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9 June 2020

language of work or name

English

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publication date

22 December 2015

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13 August 2017

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9 June 2020

volume

5

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9 June 2020

page(s)

18678

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Creative Commons Attribution 4.0 International

9 June 2020

copyright license

start time

1 December 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/srep18678

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cites work

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The predictive value of KRAS, NRAS, BRAF, PIK3CA and PTEN for anti-EGFR treatment in metastatic colorectal cancer: A systematic review and meta-analysis

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Effectors of epidermal growth factor receptor pathway: the genetic profiling ofKRAS, BRAF, PIK3CA, NRAS mutations in colorectal cancer characteristics and personalized medicine

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Simultaneous identification of 36 mutations in KRAS codons 61 and 146, BRAF, NRAS, and PIK3CA in a single reaction by multiplex assay kit.

30 September 2017

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Somatic profiling of the epidermal growth factor receptor pathway in tumors from patients with advanced colorectal cancer treated with chemotherapy ± cetuximab

30 September 2017

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High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wild-type metastatic colorectal cancer

30 September 2017

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Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival

30 September 2017

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KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in Chinese patients with colorectal cancer

30 September 2017

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PIK3CA exon 20 mutations as a potential biomarker for resistance to anti-EGFR monoclonal antibodies in KRAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis

30 September 2017

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PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers

30 September 2017

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KRAS, NRAS, PIK3CA exon 20, and BRAF genotypes in synchronous and metachronous primary colorectal cancers diagnostic and therapeutic implications

30 September 2017

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Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer

30 September 2017

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BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancer

30 September 2017

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DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset

30 September 2017

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NRAS mutations are rare in colorectal cancer

30 September 2017

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Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

30 September 2017

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Molecular markers in the treatment of metastatic colorectal cancer.

30 September 2017

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Two multiplex assays that simultaneously identify 22 possible mutation sites in the KRAS, BRAF, NRAS and PIK3CA genes

30 September 2017

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Analysis of PTEN, BRAF, and EGFR status in determining benefit from cetuximab therapy in wild-type KRAS metastatic colon cancer.

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Multi-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancer

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Mutant PIK3CA promotes cell growth and invasion of human cancer cells

30 September 2017

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30 September 2017

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30 September 2017

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Molecular spectrum of KRAS, BRAF, and PIK3CA gene mutation: determination of frequency, distribution pattern in Indian colorectal carcinoma.

30 September 2017

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Clinical usefulness of KRAS, BRAF, and PIK3CA mutations as predictive markers of cetuximab efficacy in irinotecan- and oxaliplatin-refractory Japanese patients with metastatic colorectal cancer.

21 September 2018

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Characteristics and prevalence of KRAS, BRAF, and PIK3CA mutations in colorectal cancer by high-resolution melting analysis in Taiwanese population.

21 September 2018

1 reference

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Combined mutational analysis of KRAS, NRAS and BRAF genes in Indian patients with colorectal carcinoma.

21 September 2018

1 reference

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Frequency and type of KRAS mutations in routine diagnostic analysis of metastatic colorectal cancer

21 September 2018

1 reference

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KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687048

Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687048

Mutation analysis of p53, K-ras, and BRAF genes in colorectal cancer progression

21 September 2018

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12 December 2020

High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer

1 reference

12 December 2020

K-ras mutations and cetuximab in colorectal cancer

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12 December 2020

Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases

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12 December 2020

[Detection of KRAS, BRAF, PIK3CA and EGFR gene mutations in colorectal carcinoma]

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP18678

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26691448%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 June 2020

0 references

1 reference

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9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26691448%20AND%20SRC:MED&resulttype=core&format=json