IKKβ in intestinal mesenchymal cells promotes initiation of colitis-associated cancer (Q36384120)

13 August 2017

IKKβ in intestinal mesenchymal cells promotes initiation of colitis-associated cancer (English)

1 reference

13 August 2017

Manolis Pasparakis

2

0 references

Vasiliki Koliaraki

object named as

Vasiliki Koliaraki

series ordinal

1

0 references

Giorgos Kollias

series ordinal

3

object named as

George Kollias

1 reference

PMCID

4683996

13 August 2017

language of work or name

English

0 references

publication date

30 November 2015

1 reference

Journal of Experimental Medicine

13 August 2017

1 reference

13 August 2017

212

1 reference

13 August 2017

13

1 reference

13 August 2017

2235-2251

1 reference

PMCID

4683996

describes a project that uses

13 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4683996/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis

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From sentinel cells to inflammatory culprits: cancer-associated fibroblasts in tumour-related inflammation

30 September 2017

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Inflammation meets cancer, with NF-κB as the matchmaker

30 September 2017

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Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis-associated tumorigenesis

30 September 2017

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Pten in stromal fibroblasts suppresses mammary epithelial tumours

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IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

30 September 2017

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Opposing functions of IKKbeta during acute and chronic intestinal inflammation

30 September 2017

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Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases

30 September 2017

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Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis

30 September 2017

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Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors

30 September 2017

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A global double-fluorescent Cre reporter mouse

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PPAR-gamma is expressed and NF-kB pathway is activated and correlates positively with COX-2 expression in stromal myofibroblasts surrounding colon adenocarcinomas

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IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

30 September 2017

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30 September 2017

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A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors

30 September 2017

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Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors

28 June 2018

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TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.

28 June 2018

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Epimorphin(-/-) mice are protected, in part, from acute colitis via decreased interleukin 6 signaling

28 June 2018

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Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner.

21 September 2018

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Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.

21 September 2018

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gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis.

21 September 2018

1 reference

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NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

21 September 2018

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TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

21 September 2018

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https://api.crossref.org/works/10.1084%2FJEM.20150542

The role of mutant Apc in the development of dysplasia and cancer in the mouse model of dextran sulfate sodium-induced colitis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26621453

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20150542

1 reference

13 August 2017

1 reference

13 August 2017

1 reference

PMCID

4683996