Epoxide hydrolases: structure, function, mechanism, and assay (Q36363126)

13 August 2017

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title

Epoxide hydrolases: structure, function, mechanism, and assay (English)

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13 August 2017

Michael Arand

1

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13 August 2017

Annette Cronin

series ordinal

2

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13 August 2017

Magdalena Adamska

series ordinal

3

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13 August 2017

Franz Oesch

series ordinal

4

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13 August 2017

language of work or name

English

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publication date

1 January 2005

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13 August 2017

published in

Methods in Enzymology

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13 August 2017

volume

400

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13 August 2017

page(s)

569-588

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The telltale structures of epoxide hydrolases.

13 August 2017

cites work

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7 January 2021

Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site

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7 January 2021

Cloning and molecular characterization of a soluble epoxide hydrolase from Aspergillus niger that is related to mammalian microsomal epoxide hydrolase

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7 January 2021

Catalytic triad of microsomal epoxide hydrolase: replacement of Glu404 with Asp leads to a strongly increased turnover rate

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7 January 2021

Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase

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7 January 2021

Epoxide hydrolases: new tools for the synthesis of fine organic chemicals

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7 January 2021

Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase

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7 January 2021

Limonene-1,2-epoxide hydrolase from Rhodococcus erythropolis DCL14 belongs to a novel class of epoxide hydrolases

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7 January 2021

Sequence and structure of epoxide hydrolases: a systematic analysis

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7 January 2021

cDNA cloning and expression of a soluble epoxide hydrolase from human liver

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7 January 2021

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

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7 January 2021

The N-terminal domain of mammalian soluble epoxide hydrolase is a phosphatase

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7 January 2021

Biocatalytic conversion of epoxides

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7 January 2021

Heterologous expression of human microsomal epoxide hydrolase in Saccharomyces cerevisiae. Study of the valpromide-carbamazepine epoxide interaction

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7 January 2021

Mechanistic diversity of fosfomycin resistance in pathogenic microorganisms

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7 January 2021

Mutagenicity in Salmonella assays of cyclohexane epoxide derivatives

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7 January 2021

Studies on the importance of microsomal epoxide hydrolase in the detoxification of arene oxides using the heterologous expression of the enzyme in mammalian cells

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7 January 2021

Engineered yeast cells as model to study coupling between human xenobiotic metabolizing enzymes. Simulation of the two first steps of benzo[a]pyrene activation

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7 January 2021

Microbiological transformations 50: selection of epoxide hydrolases for enzymatic resolution of 2-, 3- or 4-pyridyloxirane

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7 January 2021

Leukotriene A4 hydrolase/aminopeptidase, the gatekeeper of chemotactic leukotriene B4 biosynthesis

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7 January 2021

Leukotriene A4 hydrolase: an epoxide hydrolase with peptidase activity

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7 January 2021

Soluble mammalian epoxide hydratase: Action on juvenile hormone and other terpenoid epoxides

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7 January 2021

Recombinant expression of human microsomal epoxide hydrolase protects V79 Chinese hamster cells from styrene oxide- but not from ethylene oxide-induced DNA strand breaks.

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7 January 2021

Functional analysis of human microsomal epoxide hydrolase genetic variants

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7 January 2021

Arene oxides: a new aspect of drug metabolism

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7 January 2021

Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis gives insights into its function

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7 January 2021

Structural effects in reactivity and adduct formation of polycyclic aromatic epoxide and diol epoxide derivatives with DNA: comparison between 1-oxiranylpyrene and benzo[a]pyrenediol epoxide

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7 January 2021

Microsomal and soluble epoxide hydrolases are members of the same family of C-X bond hydrolase enzymes

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7 January 2021

Leukotriene A4 hydrolase is a zinc-containing aminopeptidase

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7 January 2021

Characterisation of a catabolic epoxide hydrolase from a Corynebacterium sp.

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7 January 2021

Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene

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7 January 2021

Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase

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7 January 2021

Visualization of a covalent intermediate between microsomal epoxide hydrolase, but not cholesterol epoxide hydrolase, and their substrates

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7 January 2021

The x-ray structure of epoxide hydrolase from Agrobacterium radiobacter AD1. An enzyme to detoxify harmful epoxides

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7 January 2021

The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity

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7 January 2021

Mammalian Epoxide Hydrases: Inducible Enzymes Catalysing the Inactivation of Carcinogenic and Cytotoxic Metabolites Derived from Aromatic and Olefinic Compounds

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7 January 2021

A radiometric assay for hepatic epoxide hydrase activity with [7-3H] styrene oxide

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7 January 2021

Existence of multiple forms of microsomal epoxide hydrolases with radically different substrate specificities

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7 January 2021

Cytosolic and microsomal epoxide hydrolases: differential properties in mammalian liver

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7 January 2021

Site-directed mutagenesis and oxygen isotope incorporation studies of the nucleophilic aspartate of haloalkane dehalogenase

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7 January 2021

Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution

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7 January 2021

Primary structure and catalytic mechanism of the epoxide hydrolase from Agrobacterium radiobacter AD1.

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7 January 2021

Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms

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7 January 2021

Soluble epoxide hydrolase variant (Glu287Arg) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterolemia: intrafamilial association study in an eight-generation hyperlipidemic kindred

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7 January 2021

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

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7 January 2021

Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation

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7 January 2021

Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema

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7 January 2021

Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function

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7 January 2021

Microbial epoxide hydrolases for preparative biotransformations

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7 January 2021

Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation

1 reference

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7 January 2021

Directed evolution of epoxide hydrolase from A. radiobacter toward higher enantioselectivity by error-prone PCR and DNA shuffling

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7 January 2021

Cloning and characterization of an epoxide hydrolase-encoding gene from Rhodotorula glutinis

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7 January 2021

The adrenaline test for enzymes

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7 January 2021

A model of sensitivity: 1,3-butadiene increases mutant frequencies and genomic damage in mice lacking a functional microsomal epoxide hydrolase gene

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7 January 2021

Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids

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7 January 2021

Structure of Aspergillus niger epoxide hydrolase at 1.8 A resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases

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7 January 2021

Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene

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7 January 2021

10.1016/S0076-6879(05)00032-7

Identifiers

DOI

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13 August 2017

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