Leukotriene A4 hydrolase/aminopeptidase, the gatekeeper of chemotactic leukotriene B4 biosynthesis (Q35875872)

10 August 2017

1 reference

title

Leukotriene A4 hydrolase/aminopeptidase, the gatekeeper of chemotactic leukotriene B4 biosynthesis (English)

1 reference

10 August 2017

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Jesper Z Haeggström

1

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PubMed ID

15339917

10 August 2017

language of work or name

English

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publication date

31 August 2004

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Journal of Biological Chemistry

10 August 2017

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10 August 2017

279

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10 August 2017

50639-50642

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10 August 2017

49

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Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

10 August 2017

1 reference

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Prostaglandins and leukotrienes: advances in eicosanoid biology

21 January 2018

1 reference

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Leukotriene B4 and BLT1 control cytotoxic effector T cell recruitment to inflamed tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R400027200

Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases

21 January 2018

1 reference

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Leukotrienes and atherosclerosis: new roles for old mediators

21 January 2018

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A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis

21 January 2018

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A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R400027200

The PPARalpha-leukotriene B4 pathway to inflammation control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Structure, function, and regulation of leukotriene A4 hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Co-localization of leukotriene a4 hydrolase with 5-lipoxygenase in nuclei of alveolar macrophages and rat basophilic leukemia cells but not neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Cloning and characterization of the human leukotriene A4 hydrolase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Leukotriene A4 hydrolase: mapping of a henicosapeptide involved in mechanism-based inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Leukotriene A4 hydrolase: protection from mechanism-based inactivation by mutation of tyrosine-378.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Regulation of leukotriene A4 hydrolase activity in endothelial cells by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Leukotriene A4 hydrolase: determination of the three zinc-binding ligands by site-directed mutagenesis and zinc analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Leukotriene A4 hydrolase: abrogation of the peptidase activity by mutation of glutamic acid-296

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Leukotriene A4 hydrolase, a bifunctional enzyme. Distinction of leukotriene A4 hydrolase and aminopeptidase activities by site-directed mutagenesis at Glu-297

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Leukotriene A4 hydrolase/aminopeptidase. Glutamate 271 is a catalytic residue with specific roles in two distinct enzyme mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Leukotriene A4 hydrolase: selective abrogation of leukotriene B4 formation by mutation of aspartic acid 375.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Leukotriene A4 hydrolase: identification of a common carboxylate recognition site for the epoxide hydrolase and aminopeptidase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Topological characteristics of helical repeat proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Crystal structures of leukotriene A4 hydrolase in complex with captopril and two competitive tight-binding inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Crystallographic study of the binding of dipeptide inhibitors to thermolysin: implications for the mechanism of catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Aminopeptidase B from the rat testis is a bifunctional enzyme structurally related to leukotriene-A4 hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Aminopeptidase B is structurally related to leukotriene-A4 hydrolase but is not a bifunctional enzyme with epoxide hydrolase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Purification and characterization of leukotriene A4 hydrolase from Xenopus laevis oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Molecular cloning and functional expression of a Caenorhabditis elegans aminopeptidase structurally related to mammalian leukotriene A4 hydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Cloning and characterization of a bifunctional leukotriene A(4) hydrolase from Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion

21 January 2018

1 reference

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An in vivo approach showing the chemotactic activity of leukotriene B(4) in acute renal ischemic-reperfusion injury

21 January 2018

1 reference

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Targeted disruption of the leukotriene B(4) receptor in mice reveals its role in inflammation and platelet-activating factor-induced anaphylaxis

21 January 2018

1 reference

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BLTR mediates leukotriene B(4)-induced chemotaxis and adhesion and plays a dominant role in eosinophil accumulation in a murine model of peritonitis

21 January 2018

1 reference

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Leukotriene A4 hydrolase in rat and human esophageal adenocarcinomas and inhibitory effects of bestatin

21 January 2018

1 reference

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Proteomics applied to the clinical follow-up of patients after allogeneic hematopoietic stem cell transplantation.

21 January 2018

1 reference

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Pharmacological characterization of SC-57461A (3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid HCl), a potent and selective inhibitor of leukotriene A(4) hydrolase II: in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R400027200

Pharmacological characterization of SC-57461A (3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid HCl), a potent and selective inhibitor of leukotriene A(4) hydrolase I: in vitro studies

21 January 2018

1 reference

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Intracellular compartmentalization of leukotriene synthesis: unexpected nuclear secrets

21 January 2018

1 reference

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The membrane organization of leukotriene synthesis

21 January 2018

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Structure of a bacteriochlorophyll a-protein from the green photosynthetic bacterium Prosthecochloris aestuarii

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21 January 2018

Identifiers

DOI

10.1074/JBC.R400027200

1 reference

10 August 2017

1 reference

PubMed ID

15339917