Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy (Q36349583)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

alternative mRNA splicing, via spliceosome

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Marco Ruella

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Nicole M Martinez

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Andrei Thomas-Tikhonenko

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

26

Yoseph Barash

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

29

Stephan A Grupp

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

20

Simon F Lacey

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Elad Jacoby

23

1 reference

ORCID Public Data File 2021

author name string

Elena Sotillo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

David M Barrett

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Kathryn L Black

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Asen Bagashev

4

1 reference

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28 February 2020

Derek Oldridge

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Glendon Wu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Claudia Lanauze

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Matthew R Gazzara

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Colleen T Harrington

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Elaine Y Chung

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Jessica Perazzelli

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Ted J Hofmann

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Shannon L Maude

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Pichai Raman

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Alejandro Barrera

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Saar Gill

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Jan J Melenhorst

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

David Allman

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Terry Fry

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Crystal Mackall

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Kristen W Lynch

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

John M Maris

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

publication date

29 October 2015

1 reference

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28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

page(s)

1282-1295

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

Regulation of alternative splicing through coupling with transcription and chromatin structure

28 February 2020

cites work

1 reference

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30 September 2017

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Targeting the B-cell receptor signaling pathway in B lymphoid malignancies

30 September 2017

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Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor-modified T cells

30 September 2017

1 reference

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New insights into cancer immunoediting and its three component phases--elimination, equilibrium and escape

30 September 2017

1 reference

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In silico to in vivo splicing analysis using splicing code models

30 September 2017

1 reference

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The Myc-miR-17-92 axis amplifies B-cell receptor signaling via inhibition of ITIM proteins: a novel lymphomagenic feed-forward loop.

30 September 2017

1 reference

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30 September 2017

1 reference

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Chromatin's thread to alternative splicing regulation

30 September 2017

1 reference

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30 September 2017

1 reference

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Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

30 September 2017

1 reference

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30 September 2017

1 reference

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Chromatin and epigenetic regulation of pre-mRNA processing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670800

A c-Myc and surface CD19 signaling amplification loop promotes B cell lymphoma development and progression in mice

30 September 2017

1 reference

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Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing

30 September 2017

1 reference

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CD19 is a major B cell receptor-independent activator of MYC-driven B-lymphomagenesis

30 September 2017

1 reference

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The RNA-binding landscapes of two SR proteins reveal unique functions and binding to diverse RNA classes.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670800

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670800

RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670800

Frequent pathway mutations of splicing machinery in myelodysplasia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670800

Noninvasive bioluminescent imaging of primary patient acute lymphoblastic leukemia: a strategy for preclinical modeling.

30 September 2017

1 reference

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T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670800

Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670800

Where splicing joins chromatin.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670800

Signal- and development-dependent alternative splicing of LEF1 in T cells is controlled by CELF2.

30 September 2017

1 reference

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Myc overexpression brings out unexpected antiapoptotic effects of miR-34a

30 September 2017

1 reference

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CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency

30 September 2017

1 reference

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B cell activator PAX5 promotes lymphomagenesis through stimulation of B cell receptor signaling

30 September 2017

1 reference

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Building of the tetraspanin web: distinct structural domains of CD81 function in different cellular compartments

30 September 2017

1 reference

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HnRNP L represses exon splicing via a regulated exonic splicing silencer

30 September 2017

1 reference

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CD19 function in central and peripheral B-cell development

30 September 2017

1 reference

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Automatic and quantitative measurement of protein-protein colocalization in live cells.

30 September 2017

1 reference

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Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics

30 September 2017

1 reference

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30 September 2017

1 reference

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ESEfinder: A web resource to identify exonic splicing enhancers

30 September 2017

1 reference

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Oscillation between B-lymphoid and myeloid lineages in Myc-induced hematopoietic tumors following spontaneous silencing/reactivation of the EBF/Pax5 pathway.

30 September 2017

1 reference

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Messenger-RNA-binding proteins and the messages they carry

30 September 2017

1 reference

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A model system for activation-induced alternative splicing of CD45 pre-mRNA in T cells implicates protein kinase C and Ras.

30 September 2017

1 reference

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Construction and characterisation of a functional CD19 specific single chain Fv fragment for immunotherapy of B lineage leukaemia and lymphoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670800

Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer

30 September 2017

1 reference

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The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670800

Phase II trial of the anti-CD19 bispecific T cell-engager blinatumomab shows hematologic and molecular remissions in patients with relapsed or refractory B-precursor acute lymphoblastic leukemia

30 September 2017

1 reference

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CD19 function in early and late B cell development. II. CD19 facilitates the pro-B/pre-B transition

22 September 2018

1 reference

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CD19 function in early and late B cell development: I. Maintenance of follicular and marginal zone B cells requires CD19-dependent survival signals

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670800

The physiologic role of CD19 cytoplasmic tyrosines

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670800

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4670800

CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26516065

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Preparation and characterization of a chimeric CD 19 monoclonal antibody

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26516065

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/2159-8290.CD-15-1020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26516065%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference