Sulforaphane Bioavailability and Chemopreventive Activity in Women Scheduled for Breast Biopsy (Q36349551)

13 August 2017

Sulforaphane Bioavailability and Chemopreventive Activity in Women Scheduled for Breast Biopsy (English)

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13 August 2017

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5 June 2020

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Jackilen Shannon

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5 June 2020

author name string

Lauren L Atwell

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Motomi Mori

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Paige Farris

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5 June 2020

John T Vetto

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Arpana M Naik

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Karen Y Oh

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Philippe Thuillier

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Emily Ho

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5 June 2020

publication date

28 October 2015

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Cancer Prevention Research

13 August 2017

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5 June 2020

volume

8

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issue

12

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5 June 2020

page(s)

1184-1191

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Dietary Glucosinolates Sulforaphane, Phenethyl Isothiocyanate, Indole-3-Carbinol/3,3'-Diindolylmethane: Anti-Oxidative Stress/Inflammation, Nrf2, Epigenetics/Epigenomics and In Vivo Cancer Chemopreventive Efficacy

5 June 2020

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Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase-treated broccoli sprout extract.

30 September 2017

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Ductal carcinoma in situ: a brief review of treatment variation and impacts on patients and society

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Dietary Sulforaphane in Cancer Chemoprevention: The Role of Epigenetic Regulation and HDAC Inhibition

30 September 2017

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Comparison of isothiocyanate metabolite levels and histone deacetylase activity in human subjects consuming broccoli sprouts or broccoli supplement

30 September 2017

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Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design.

30 September 2017

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Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice

30 September 2017

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Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly

30 September 2017

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Sulforaphane inhibits the growth of KPL-1 human breast cancer cells in vitro and suppresses the growth and metastasis of orthotopically transplanted KPL-1 cells in female athymic mice

30 September 2017

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Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells

30 September 2017

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Variation of glucoraphanin metabolism in vivo and ex vivo by human gut bacteria.

30 September 2017

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Change in lifestyle behaviors and medication use after a diagnosis of ductal carcinoma in situ

30 September 2017

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Examination of the expanding pathways for the regulation of p21 expression and activity

30 September 2017

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National Institutes of Health State-of-the-Science Conference statement: Diagnosis and Management of Ductal Carcinoma In Situ September 22-24, 2009.

30 September 2017

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Ductal carcinoma in situ of the breast: a systematic review of incidence, treatment, and outcomes

30 September 2017

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Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6

30 September 2017

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Protein acetylation and histone deacetylase expression associated with malignant breast cancer progression

30 September 2017

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Combinatorial patterns of histone acetylations and methylations in the human genome

30 September 2017

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Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines

30 September 2017

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Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.

30 September 2017

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Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice

30 September 2017

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Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China

30 September 2017

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Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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29 June 2018

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Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis

22 September 2018

1 reference

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Cruciferous vegetable intake questionnaire improves cruciferous vegetable intake estimates.

22 September 2018

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Activity of suberoylanilide hydroxamic Acid against human breast cancer cells with amplification of her-2.

22 September 2018

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Quantitative determination of intact glucosinolates in broccoli, broccoli sprouts, Brussels sprouts, and cauliflower by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry

22 September 2018

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Sulforaphane halts breast cancer cell growth

22 September 2018

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A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.

22 September 2018

1 reference

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The effect of cruciferous and leguminous sprouts on genotoxicity, in vitro and in vivo

22 September 2018

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Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines

22 September 2018

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Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo.

22 September 2018

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Transcriptional activation of estrogen receptor alpha in human breast cancer cells by histone deacetylase inhibition

22 September 2018

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12 December 2020

Safety, Tolerance, and Metabolism of Broccoli Sprout Glucosinolates and Isothiocyanates: A Clinical Phase I Study

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12 December 2020

Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects

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12 December 2020

Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype

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12 December 2020

Prostaglandin F2alpha suppresses rat steroidogenic acute regulatory protein expression via induction of Yin Yang 1 protein and recruitment of histone deacetylase 1 protein

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12 December 2020

10.1158/1940-6207.CAPR-15-0119

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5 June 2020

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