HLA-DM constrains epitope selection in the human CD4 T cell response to vaccinia virus by favoring the presentation of peptides with longer HLA-DM-mediated half-lives (Q36303660)

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English	HLA-DM constrains epitope selection in the human CD4 T cell response to vaccinia virus by favoring the presentation of peptides with longer HLA-DM-mediated half-lives	scientific article

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

HLA-DM constrains epitope selection in the human CD4 T cell response to vaccinia virus by favoring the presentation of peptides with longer HLA-DM-mediated half-lives (English)

1 reference

Europe PubMed Central

13 August 2017

object named as

vaccinia virus

1 reference

based on heuristic

inferred from title

author name string

Liusong Yin

1

1 reference

Europe PubMed Central

13 August 2017

J Mauricio Calvo-Calle

2

1 reference

Europe PubMed Central

13 August 2017

Omar Dominguez-Amorocho

3

1 reference

Europe PubMed Central

13 August 2017

Lawrence J Stern

4

1 reference

Europe PubMed Central

13 August 2017

language of work or name

0 references

publication date

10 September 2012

1 reference

Europe PubMed Central

13 August 2017

Journal of Immunology

1 reference

Europe PubMed Central

13 August 2017

189

1 reference

Europe PubMed Central

13 August 2017

8

1 reference

Europe PubMed Central

13 August 2017

3983-3994

1 reference

Europe PubMed Central

13 August 2017

The mechanism of HLA-DM induced peptide exchange in the MHC class II antigen presentation pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Conformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchange

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Peptide binding predictions for HLA DR, DP and DQ molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

A reductionist cell-free major histocompatibility complex class II antigen processing system identifies immunodominant epitopes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Heterologous immunity between viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Cutting edge: HLA-DM-mediated peptide exchange functions normally on MHC class II-peptide complexes that have been weakened by elimination of a conserved hydrogen bond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Peptide-MHC class II complex stability governs CD4 T cell clonal selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Cutting edge: HLA-DM functions through a mechanism that does not require specific conserved hydrogen bonds in class II MHC-peptide complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

HLA-DM mediates peptide exchange by interacting transiently and repeatedly with HLA-DR1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Autoimmune T cell responses in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

HLA-DM mediates epitope selection by a "compare-exchange" mechanism when a potential peptide pool is available

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Vaccinia peptides eluted from HLA-DR1 isolated from virus-infected cells are recognized by CD4+ T cells from a vaccinated donor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

HLA-DM negatively regulates HLA-DR4-restricted collagen pathogenic peptide presentation and T cell recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

An extremely diverse CD4 response to vaccinia virus in humans is revealed by proteome-wide T-cell profiling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Human CD4+ T cell epitopes from vaccinia virus induced by vaccination or infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

The impact of DM on MHC class II-restricted antigen presentation can be altered by manipulation of MHC-peptide kinetic stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

The immune epitope database and analysis resource: from vision to blueprint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Profiling the humoral immune response to infection by using proteome microarrays: high-throughput vaccine and diagnostic antigen discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

HLA-DMA*0103 and HLA-DMB*0104 alleles as novel prognostic factors in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Expansion and functional relevance of high-avidity myelin-specific CD4+ T cells in multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Epitope dominance, competition and T cell affinity maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Labeling antigen-specific CD4(+) T cells with class II MHC oligomers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Rheumatoid arthritis (RA)-associated HLA-DR alleles form less stable complexes with class II-associated invariant chain peptide than non-RA-associated HLA-DR alleles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Negative selection during the peripheral immune response to antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

The down-regulation of HLA-DM gene expression in rheumatoid arthritis is not related to their promoter polymorphism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

T cells compete for access to antigen-bearing antigen-presenting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

DM determines the cryptic and immunodominant fate of T cell epitopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

SYFPEITHI: database for MHC ligands and peptide motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Immunodominance of a low-affinity major histocompatibility complex-binding myelin basic protein epitope (residues 111-129) in HLA-DR4 (B1*0401) subjects is associated with a restricted T cell receptor repertoire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Editing of the HLA-DR-peptide repertoire by HLA-DM

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

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Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

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The meaning and use of the area under a receiver operating characteristic (ROC) curve

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Statistical approaches to the analysis of receiver operating characteristic (ROC) curves

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30 September 2017

Receiver operating characteristic (ROC) methodology: the state of the art.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

MHC class II-associated invariant chain contains a sorting signal for endosomal compartments

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Identification of a motif for HLA-DR1 binding peptides using M13 display libraries

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Intracellular transport of invariant chain-MHC class II complexes to the peptide-loading compartment

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

30 September 2017

Mediation by HLA-DM of dissociation of peptides from HLA-DR.

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30 September 2017

The majority of immunogenic epitopes generate CD4+ T cells that are dependent on MHC class II-bound peptide-flanking residues

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Differential tolerance is induced in T cells recognizing distinct epitopes of myelin basic protein.

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29 June 2018

Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding

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29 June 2018

Comparison of the safety and immunogenicity of ACAM1000, ACAM2000 and Dryvax in healthy vaccinia-naive adults.

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22 September 2018

Vaccinia virus-specific CD4+ T cell responses target a set of antigens largely distinct from those targeted by CD8+ T cell responses

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22 September 2018

Effect of decreasing the affinity of the class II-associated invariant chain peptide on the MHC class II peptide repertoire in the presence or absence of H-2M.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

22 September 2018

Structural factors contributing to DM susceptibility of MHC class II/peptide complexes

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22 September 2018

Relationship between kinetic stability and immunogenicity of HLA-DR4/peptide complexes.

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22 September 2018

Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP.

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22 September 2018

Specific and general HLA-DR binding motifs: comparison of algorithms.

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22 September 2018

Empty and peptide-loaded class II major histocompatibility complex proteins produced by expression in Escherichia coli and folding in vitro.

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22 September 2018

Low avidity recognition of self-antigen by T cells permits escape from central tolerance.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466378

22 September 2018

Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices

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5 December 2018

Polymorphism of the HLA-DMA and DMB genes in Rheumatoid Arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22966084

12 December 2020

based on heuristic

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Editing of an immunodominant epitope of glutamate decarboxylase by HLA-DM

1 reference

https://pubmed.ncbi.nlm.nih.gov/22966084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: H-2DM is responsible for the large differences in presentation among peptides selected by I-Ak during antigen processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/22966084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-affinity binding of an influenza hemagglutinin-derived peptide to purified HLA-DR

1 reference

https://pubmed.ncbi.nlm.nih.gov/22966084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathologic role and temporal appearance of newly emerging autoepitopes in relapsing experimental autoimmune encephalomyelitis

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https://pubmed.ncbi.nlm.nih.gov/22966084

12 December 2020

based on heuristic

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Cutting edge: introduction of an endopeptidase cleavage motif into a determinant flanking region of hen egg lysozyme results in enhanced T cell determinant display

1 reference

https://pubmed.ncbi.nlm.nih.gov/22966084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance

1 reference

https://pubmed.ncbi.nlm.nih.gov/22966084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HLA-DM is present in one-fifth the amount of HLA-DR in the class II peptide-loading compartment where it associates with leupeptin-induced peptide (LIP)-HLA-DR complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22966084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1200626

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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