The impact of DM on MHC class II-restricted antigen presentation can be altered by manipulation of MHC-peptide kinetic stability (Q36238108)

13 August 2017

The impact of DM on MHC class II-restricted antigen presentation can be altered by manipulation of MHC-peptide kinetic stability (English)

1 reference

13 August 2017

Christopher A Lazarski

series ordinal

1

object named as

Christopher A Lazarski

1 reference

13 August 2017

Francisco A Chaves

2

1 reference

PMCID

2121212

13 August 2017

Andrea J Sant

series ordinal

3

1 reference

PMCID

2121212

13 August 2017

language of work or name

English

0 references

publication date

8 May 2006

1 reference

Journal of Experimental Medicine

13 August 2017

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13 August 2017

203

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13 August 2017

5

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13 August 2017

1319-1328

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The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Antigen persistence is required throughout the expansion phase of a CD4(+) T cell response

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Cell biology of antigen processing in vitro and in vivo

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Cutting edge: TCR contacts as anchors: effects on affinity and HLA-DM stability

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Formation of two peptide/MHC II isomers is catalyzed differentially by HLA-DM.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

The proliferative capacity of individual naive CD4(+) T cells is amplified by prolonged T cell antigen receptor triggering

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Identification of the lateral interaction surfaces of human histocompatibility leukocyte antigen (HLA)-DM with HLA-DR1 by formation of tethered complexes that present enhanced HLA-DM catalysis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

The kinetic basis of peptide exchange catalysis by HLA-DM

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Energetic asymmetry among hydrogen bonds in MHC class II*peptide complexes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Cutting edge: editing of recycling class II:peptide complexes by HLA-DM.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

HLA-DM recognizes the flexible conformation of major histocompatibility complex class II.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Determination of the HLA-DM interaction site on HLA-DR molecules

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

DM determines the cryptic and immunodominant fate of T cell epitopes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Identification of destabilizing residues in HLA class II-selected bacteriophage display libraries edited by HLA-DM.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Crystal structure of mouse H2-M

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

The structure of HLA-DM, the peptide exchange catalyst that loads antigen onto class II MHC molecules during antigen presentation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Binding affinity independent contribution of peptide length to the stability of peptide-HLA-DR complexes in live antigen presenting cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Impaired antigen presentation by murine I-Ad class II MHC molecules expressed in normal and HLA-DM-defective human B cell lines.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

In the absence of the invariant chain, HLA-DR molecules display a distinct array of peptides which is influenced by the presence or absence of HLA-DM

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Presentation of abundant endogenous class II DR-restricted antigens by DM-negative B cell lines.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

How HLA-DM edits the MHC class II peptide repertoire: survival of the fittest?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Editing of the HLA-DR-peptide repertoire by HLA-DM

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

DM-mediated release of a naturally occurring invariant chain degradation intermediate from MHC class II molecules

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Effect of HLA-DM transfection on hen egg lysozyme presentation by T2.Ak cells.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Major histocompatibility complex class II-restricted presentation of an internally synthesized antigen displays cell-type variability and segregates from the exogenous class II and endogenous class I presentation pathways

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Expression cloning of a protective Leishmania antigen

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Dominance and crypticity of T cell antigenic determinants

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates peptide loading

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Mediation by HLA-DM of dissociation of peptides from HLA-DR.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Affinity chromatographic isolation of the periplasmic maltose binding protein ofEscherichia coli

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Antigen-presenting cells and the selection of immunodominant epitopes.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

T cell receptor recognition of MHC class II alloantigens is highly cell type dependent.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121212

Structural factors contributing to DM susceptibility of MHC class II/peptide complexes

29 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060058

Enhanced catalytic action of HLA-DM on the exchange of peptides lacking backbone hydrogen bonds between their N-terminal region and the MHC class II alpha-chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060058

Replacement of the membrane proximal region of I-A(d) MHC class II molecule with I-E-derived sequences promotes production of an active and stable soluble heterodimer without altering peptide-binding specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060058

TH1 and TH2 cell antigen receptors in experimental leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060058

Energetics and cooperativity of the hydrogen bonding and anchor interactions that bind peptides to MHC class II protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060058

Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060058

Cutting edge: H-2DM is responsible for the large differences in presentation among peptides selected by I-Ak during antigen processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060058

The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060058

Expression of heterologous peptides at two permissive sites of the MalE protein: antigenicity and immunogenicity of foreign B-cell and T-cell epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060058

T cell fitness determined by signal strength

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060058

Repeated antigen exposure is necessary for the differentiation, but not the initial proliferation, of naive CD4(+) T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060058

A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060058

21 January 2018

Identifiers

DOI

10.1084/JEM.20060058

1 reference

13 August 2017

1 reference

13 August 2017

1 reference

PMCID

2121212