Structural basis of the allosteric inhibitor interaction on the HIV-1 reverse transcriptase RNase H domain. (Q36300994)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846652%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Structural basis of the allosteric inhibitor interaction on the HIV-1 reverse transcriptase RNase H domain (English)

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9 February 2020

1 reference

1

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9 February 2020

author name string

Lakshmi Menon

2

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9 February 2020

Nataliya S Myshakina

3

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9 February 2020

Jinwoo Ahn

4

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9 February 2020

Michael A Parniak

5

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9 February 2020

Rieko Ishima

6

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9 February 2020

publication date

31 August 2012

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Chemical Biology and Drug Design

9 February 2020

published in

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9 February 2020

volume

80

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9 February 2020

page(s)

706-716

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9 February 2020

issue

5

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Identification of alternative binding sites for inhibitors of HIV-1 ribonuclease H through comparative analysis of virtual enrichment studies

9 February 2020

cites work

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Allosteric suppression of HIV-1 reverse transcriptase structural dynamics upon inhibitor binding

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30 September 2017

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30 September 2017

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Non-nucleoside reverse transcriptase inhibitors (NNRTIs): past, present, and future

30 September 2017

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HIV-1 Reverse Transcriptase Structure with RNase H Inhibitor Dihydroxy Benzoyl Naphthyl Hydrazone Bound at a Novel Site

30 September 2017

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Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones

30 September 2017

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Taking aim at a moving target: designing drugs to inhibit drug-resistant HIV-1 reverse transcriptases

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase

30 September 2017

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Solution structural dynamics of HIV-1 reverse transcriptase heterodimer

30 September 2017

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29 June 2018

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The interaction of illimaquinone, a selective inhibitor of the RNase H activity, with the reverse transcriptases of human immunodeficiency and murine leukemia retroviruses

29 June 2018

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29 June 2018

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29 June 2018

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21 January 2018

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Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities

21 January 2018

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6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro

21 January 2018

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21 January 2018

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21 January 2018

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Inhibitor binding alters the directions of domain motions in HIV-1 reverse transcriptase

21 January 2018

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12 December 2020

Mechanism of DNA Strand Transfer Reactions Catalyzed by HIV-1 Reverse Transcriptase

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12 December 2020

Mutating a conserved motif of the HIV-1 reverse transcriptase palm subdomain alters primer utilization

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12 December 2020

Solution structure and dynamics of a serpin reactive site loop using interleukin 1beta as a presentation scaffold

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12 December 2020

Inhibitors of HIV-1 reverse transcriptase

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12 December 2020

Identifiers

DOI

10.1111/CBDD.12010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846652%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846652%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

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